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Query: NC_007146:1405459:1416192 Haemophilus influenzae 86-028NP, complete genome

Start: 1416192, End: 1416836, Length: 645

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This nontypeable strain is a clinical isolate from a pediatric patient with otitis media from Columbus Children's Hospital. Causes respiratory tract infections primarily in children. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009567:904922:916820916820917470651Haemophilus influenzae PittGG chromosome, complete genomehypothetical protein1e-105382
NC_014922:1360000:137997013799701380665696Haemophilus influenzae F3047 chromosome, complete genomehypothetical protein2e-105381
NC_014922:825396:836999836999837649651Haemophilus influenzae F3047 chromosome, complete genomehypothetical protein3e-103374
NC_016809:1778000:178516017851601785810651Haemophilus influenzae 10810, complete genomehypothetical protein7e-102369
NC_012791:2590500:259572125957212596386666Variovorax paradoxus S110 chromosome 1, complete genomehypothetical protein2e-25115
NC_010002:3509506:352310635231063523885780Delftia acidovorans SPH-1, complete genomehypothetical protein9e-23106