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Query: NC_007146:1405459:1414350 Haemophilus influenzae 86-028NP, complete genome

Start: 1414350, End: 1415696, Length: 1347

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This nontypeable strain is a clinical isolate from a pediatric patient with otitis media from Columbus Children's Hospital. Causes respiratory tract infections primarily in children. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014922:825396:8354008354008365031104Haemophilus influenzae F3047 chromosome, complete genomehypothetical protein3e-176618
NC_010067:2529750:2590424259042425917041281Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein2e-143509
NC_014393:4323368:4339216433921643405051290Clostridium cellulovorans 743B chromosome, complete genomehypothetical protein3e-131468
NC_009567:904922:917967917967918746780Haemophilus influenzae PittGG chromosome, complete genomehypothetical protein9e-92337
NC_009256:1253384:1258706125870612597431038Burkholderia vietnamiensis G4 chromosome 1, complete sequencehypothetical protein1e-57224
NC_017033:1557981:156506415650641565897834Frateuria aurantia DSM 6220 chromosome, complete genomehypothetical protein9e-55214
NC_009255:1344000:135056713505671351388822Burkholderia vietnamiensis G4 chromosome 2, complete sequencehypothetical protein1e-46187
NC_007712:1712667:172601817260181726647630Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein3e-40166
NC_007712:1893066:189869118986911899266576Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein3e-32140
NC_006905:368942:381513381513381770258Salmonella enterica subsp. enterica serovar Choleraesuis str43L-like protein3e-22106
NC_013132:4803460:482649248264924827349858Chitinophaga pinensis DSM 2588, complete genomepentapeptide repeat containing protein5e-1995.9