Pre_GI: BLASTP Hits

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Query: NC_006570:1526071:1542421 Francisella tularensis subsp. tularensis Schu 4, complete genome

Start: 1542421, End: 1543146, Length: 726

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016937:1525914:154226415422641542989726Francisella tularensis subsp. tularensis TI0902 chromosome,hypothetical protein4e-140497
NC_016933:1601821:161817116181711618896726Francisella tularensis TIGB03 chromosome, complete genomehypothetical protein4e-140497
NC_008245:1525877:154222715422271542952726Francisella tularensis subsp. tularensis FSC 198, complete genomehypothetical protein4e-140497
NC_009257:775538:780041780041780766726Francisella tularensis subsp. tularensis WY96-3418 chromosome,hypothetical protein5e-140496
NC_008369:291640:292948292948293673726Francisella tularensis subsp. holarctica OSU18, complete genomehypothetical protein6e-139493
NC_009749:289695:291003291003291728726Francisella tularensis subsp. holarctica FTA, complete genomehypothetical protein6e-139493
NC_007880:290059:291367291367292092726Francisella tularensis subsp. holarctica, complete genomehypothetical protein6e-139493
NC_008601:1560482:159429515942951595020726Francisella tularensis subsp. novicida U112, complete genomehypothetical protein3e-138490