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Query: NC_006570:1526071:1529717 Francisella tularensis subsp. tularensis Schu 4, complete genome

Start: 1529717, End: 1530112, Length: 396

Host Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This subspecies is virulent in humans, and the strain is a clinical isolate that is also virulent in an animal model. Originally isolated from a human case of tularemia in 1951. There are a large number of insertion sequences including a mariner element, which is a transposon typically found in eukaryotes and is the first instance of this element to be found in a microbe, which may have acquired it during transit through one of the insect vectors. Causative agent of tularemia. This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016937:1525914:152956015295601529955396Francisella tularensis subsp. tularensis TI0902 chromosome,Diadenosine tetraphosphate (Ap4A) hydrolase-related HIT family hydrolase3e-73273
NC_016933:1601821:160546716054671605862396Francisella tularensis TIGB03 chromosome, complete genomeDiadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase3e-73273
NC_008245:1525877:152952315295231529918396Francisella tularensis subsp. tularensis FSC 198, complete genomeconservered hypothetical protein3e-73273
NC_018012:3102215:310330631033063103725420Thiocystis violascens DSM 198 chromosome, complete genomeHIT family hydrolase, diadenosine tetraphosphate hydrolase3e-24110
NC_002516:1031386:104583210458321046461630Pseudomonas aeruginosa PAO1, complete genomehypothetical protein2e-22103
NC_017271:3057161:308108330810833081520438Xanthomonas campestris pv. raphani 756C chromosome, completediadenosine tetraphosphate hydrolase3e-22103
NC_010995:2798000:281970928197092820131423Cellvibrio japonicus Ueda107, complete genomehistidine triad family protein2e-1890.9
NC_006512:728281:742377742377742781405Idiomarina loihiensis L2TR, complete genomeHIT family hydrolase5e-1889.7
NC_007912:1173752:117562711756271176094468Saccharophagus degradans 2-40, complete genomePectate lyase/Amb allergen5e-1579.7
NC_017518:1701958:170374617037461704150405Neisseria meningitidis NZ-05/33 chromosome, complete genomehistidine triad family protein3e-0857
NC_009850:1011293:101903110190311019390360Arcobacter butzleri RM4018, complete genomeHIT family protein7e-0855.8
NC_008825:2889933:291052129105212910964444Methylibium petroleiphilum PM1, complete genomehypothetical protein6e-0752.8
NC_007520:1627978:164393916439391644331393Thiomicrospira crunogena XCL-2, complete genomehypothetical protein1e-0652