Pre_GI: BLASTP Hits

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Query: NC_006085:925604:957565 Propionibacterium acnes KPA171202, complete genome

Start: 957565, End: 958218, Length: 654

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013364:5083949:511058451105845111234651Escherichia coli O111:H- str. 11128, complete genome3-keto-L-gulonate-6-phosphate decarboxylase9e-48189
NC_004432:936500:942507942507943160654Mycoplasma penetrans HF-2, complete genomehexulose-6-phosphate synthase3e-35148
NC_014921:22828:298582985830511654Mycoplasma fermentans M64 chromosome, complete genome3-hexulose-6-phosphate synthase2e-34145
NC_006360:518808:520385520385521053669Mycoplasma hyopneumoniae 232, complete genomehexulose-6-phosphate synthase1e-33142
NC_011083:2847318:286819128681912868826636Salmonella enterica subsp. enterica serovar Heidelberg str. SL476,3-hexulose-6-phosphate synthase1e-20100
NC_009648:3224495:324751032475103248145636Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeputative hexulose 6 phosphate synthase1e-20100
NC_016810:2871689:291625129162512916886636Salmonella enterica subsp. enterica serovar Typhimurium str3-hexulose-6-phosphate synthase1e-20100
NC_016856:2896630:291391029139102914545636Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative hexulose 6 phosphate synthase1e-20100
NC_016857:2871689:291625129162512916886636Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative hexulose 6 phosphate synthase1e-20100
NC_016863:2844883:286216328621632862798636Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative hexulose 6 phosphate synthase1e-20100
NC_017046:2896651:291499229149922915627636Salmonella enterica subsp. enterica serovar Typhimurium str. 7983-hexulose-6-phosphate synthase1e-20100
NC_010556:2328303:233342623334262334064639Exiguobacterium sibiricum 255-15, complete genome3-hexulose-6-phosphate synthase1e-1996.3
NC_011751:3048490:306777830677783068413636Escherichia coli UMN026 chromosome, complete genomeputative 3-hexulose-6-phosphate synthase from bacteriophage origin2e-1995.9
NC_018665:2163713:217160321716032172241639Exiguobacterium antarcticum B7 chromosome, complete genome3-hexulose-6-phosphate synthase4e-1994.7
NC_009848:2335265:233803423380342338666633Bacillus pumilus SAFR-032, complete genome3-hexulose-6-phosphate synthase5e-1891.3
NC_009480:1261961:128670812867081287331624Clavibacter michiganensis subsp. michiganensis NCPPB 382, completeputative hexulose-6-phosphate synthase8e-1890.5
NC_003413:214120:2354892354892367931305Pyrococcus furiosus DSM 3638, complete genomehexulose-6-phosphate synthase (d-arabino 3-hexulose 6-phosphate formaldehyde lyase)1e-1686.7
NC_020210:2133996:215551921555192156154636Geobacillus sp. GHH01, complete genome3-hexulose-6-phosphate synthase1e-1686.3
NC_009712:669647:6707536707536720391287Candidatus Methanoregula boonei 6A8, complete genomebifunctional hexulose-6-phosphate synthase/ribonuclease regulator3e-1478.6
NC_006624:405966:4068414068414080611221Thermococcus kodakarensis KOD1, complete genomebifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase4e-1478.2
NC_013665:849508:8543158543158556011287Methanocella paludicola SANAE, complete genome3-hexulose-6-phosphate synthase5e-1477.8
NC_012968:325529:343956343956344618663Methylotenera mobilis JLW8, complete genomeOrotidine 5'-phosphate decarboxylase1e-1376.3
NC_007168:2415361:241748124174812418113633Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein3e-1271.6
NC_017338:588983:607217607217607849633Staphylococcus aureus subsp. aureus JKD6159 chromosome, complete3-hexulose-6-phosphate synthase1e-1170.1
NC_007622:567500:586936586936587568633Staphylococcus aureus RF122, complete genomeprobable 3-hexulose-6-phosphate synthase2e-1169.3
NC_019977:253895:2734122734122745631152Methanomethylovorans hollandica DSM 15978, complete genomeDemethylmenaquinone methyltransferase2e-1169.3
NC_002952:610462:629493629493630125633Staphylococcus aureus subsp. aureus MRSA252, complete genomeputative hexulose-6-phosphate synthase2e-1168.9
NC_003923:591000:613401613401614033633Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein2e-1168.9
NC_002953:588437:612092612092612724633Staphylococcus aureus subsp. aureus MSSA476, complete genomeputative hexulose-6-phosphate synthase2e-1168.9
NC_009641:597000:619249619249619881633Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein3e-1168.6
NC_017341:618649:642198642198642830633Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,3-hexulose-6-phosphate synthase3e-1168.6
NC_017347:616000:638306638306638938633Staphylococcus aureus subsp. aureus T0131 chromosome, complete3-hexulose-6-phosphate synthase3e-1168.6
NC_010525:612000:632246632246632914669Thermoproteus neutrophilus V24Sta, complete genomeOrotidine 5'-phosphate decarboxylase1e-1066.6
NC_009073:529148:539217539217539870654Pyrobaculum calidifontis JCM 11548, complete genomeOrotidine 5'-phosphate decarboxylase2e-0962.4
NC_014507:817977:8210308210308222261197Methanoplanus petrolearius DSM 11571 chromosome, complete genomeformaldehyde-activating enzyme4e-0961.6
NC_007955:2074844:2095822209582220970121191Methanococcoides burtonii DSM 6242, complete genomeOrotidine 5'-phosphate decarboxylase9e-0857
NC_009376:1633283:164009216400921640757666Pyrobaculum arsenaticum DSM 13514 chromosome, complete genomeorotidine 5'-phosphate decarboxylase2e-0755.8
NC_019977:253895:2548442548442560401197Methanomethylovorans hollandica DSM 15978, complete genomeformaldehyde-activating enzyme2e-0652.8