Pre_GI: BLASTP Hits

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Query: NC_006085:925604:956567 Propionibacterium acnes KPA171202, complete genome

Start: 956567, End: 957559, Length: 993

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014921:22828:2563325633266941062Mycoplasma fermentans M64 chromosome, complete genomehypothetical protein2e-52206
NC_014915:2092678:212382321238232124815993Geobacillus sp. Y412MC52 chromosome, complete genomearyldialkylphosphatase4e-44179
NC_013411:2975364:298389229838922984884993Geobacillus sp. Y412MC61, complete genomearyldialkylphosphatase4e-44179
NC_008578:591357:600457600457601455999Acidothermus cellulolyticus 11B, complete genomearyldialkylphosphatase7e-37154
NC_004432:936500:946265946265946957693Mycoplasma penetrans HF-2, complete genomephosphotriesterase family protein5e-35148
NC_011295:33500:335943359434484891Coprothermobacter proteolyticus DSM 5265, complete genomeputative phosphotriesterase2e-32140
NC_013198:394000:425426425426426310885Lactobacillus rhamnosus GG, complete genomemetal-dependent hydrolase with the TIM-barrel fold4e-30132
NC_014831:2133060:216311321631132164108996Thermaerobacter marianensis DSM 12885 chromosome, complete genomeAryldialkylphosphatase6e-28125
NC_014363:8228:203462034621254909Olsenella uli DSM 7084 chromosome, complete genomearyldialkylphosphatase6e-27121
NC_006270:718169:727058727058727942885Bacillus licheniformis ATCC 14580, complete genomezin-ion binding putative hydrolase2e-26120
NC_006322:717953:726841726841727725885Bacillus licheniformis ATCC 14580, complete genomehypothetical protein2e-26120
NC_013892:114884:1358911358911369791089Xenorhabdus bovienii SS-2004 chromosome, complete genomephosphotriesterase with metallo-dependent hydrolase domain2e-21103
NC_012726:287637:287637287637288581945Sulfolobus islandicus M.16.4 chromosome, complete genomeAryldialkylphosphatase5e-1892
NC_007181:1963887:196796119679611968908948Sulfolobus acidocaldarius DSM 639, complete genomeparathion hydrolase2e-1790.1
NC_013850:2685835:2711775271177527128541080Klebsiella variicola At-22 chromosome, complete genomeAryldialkylphosphatase1e-1377.8
NC_011283:2684046:2706979270697927080581080Klebsiella pneumoniae 342 chromosome, complete genomephosphotriesterase family protein1e-1377.8
NC_009648:1914621:1915605191560519166841080Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeputative hydrolase2e-1376.6
NC_012731:2650603:2651617265161726526961080Klebsiella pneumoniae NTUH-K2044 chromosome, complete genomeputative hydrolase2e-1376.6
NC_016845:2691129:2692134269213426932131080Klebsiella pneumoniae subsp. pneumoniae HS11286 chromosome,putative hydrolase2e-1376.6
NC_010676:2658495:2681354268135426824031050Burkholderia phytofirmans PsJN chromosome 2, complete sequencearyldialkylphosphatase9e-1271.2
NC_015312:2278566:2287615228761522886791065Pseudonocardia dioxanivorans CB1190 chromosome, complete genomearyldialkylphosphatase1e-1171.2
NC_015312:2278566:2304306230430623053731068Pseudonocardia dioxanivorans CB1190 chromosome, complete genomearyldialkylphosphatase2e-0860.1