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Query: NC_006085:925604:949031 Propionibacterium acnes KPA171202, complete genome

Start: 949031, End: 949723, Length: 693

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008593:1859861:1879710187971018809211212Clostridium novyi NT, complete genomeHypothetical UPF0261 protein5e-39160
NC_019974:3013338:3041141304114130423491209Natronococcus occultus SP4, complete genomehypothetical protein4e-37154
NC_017297:1700000:1708587170858717097951209Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein6e-37154
NC_009699:1698951:1708456170845617096641209Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein6e-37154
NC_012658:1658505:1667646166764616688541209Clostridium botulinum Ba4 str. 657 chromosome, complete genomehypothetical protein2e-36152
NC_014298:310964:3280773280773293031227Halalkalicoccus jeotgali B3 plasmid 1, complete sequencehypothetical protein8e-36150
NC_014328:2518081:2522853252285325240611209Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein6e-36150
NC_013406:5954472:5955352595535259565631212Paenibacillus sp. Y412MC10 chromosome, complete genomehypothetical protein2e-34145
NC_017955:2327500:2344452234445223457381287Modestobacter marinus, complete genomehypothetical protein5e-28124
NC_004547:1062410:1080117108011710813251209Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein2e-27122
NC_012883:1462000:1478525147852514799551431Thermococcus sibiricus MM 739, complete genomehypothetical protein1e-1789.7
NC_007517:2342607:2369593236959323708491257Geobacter metallireducens GS-15, complete genomehypothetical protein2e-1375.9