Pre_GI: BLASTP Hits

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Query: NC_006085:925604:925604 Propionibacterium acnes KPA171202, complete genome

Start: 925604, End: 927295, Length: 1692

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012803:3691:3912039120426443525Micrococcus luteus NCTC 2665, complete genomeconjugative relaxase domain protein, TrwC/TraI family3e-166585
NC_013169:612456:6365886365886401423555Kytococcus sedentarius DSM 20547, complete genomeTrwC relaxase3e-157555
NC_014215:1243125:1244941124494112479553015Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,7e-154544
NC_014830:3387479:3426762342676234300523291Intrasporangium calvum DSM 43043 chromosome, complete genomeTrwC relaxase2e-71270
NC_013235:2129982:2155767215576721594623696Nakamurella multipartita DSM 44233, complete genomeTrwC relaxase1e-61237
NC_015514:3508022:3522251352225135251422892Cellulomonas fimi ATCC 484 chromosome, complete genomeconjugative relaxase domain-containing protein3e-56219
NC_008699:1673181:1673181167318116785745394Nocardioides sp. JS614, complete genomeDNA primase catalytic core, N-terminal domain6e-49195
NC_017955:3670670:3715007371500737204815475Modestobacter marinus, complete genomeDNA primase5e-47189
NC_017955:1667500:1668039166803916735375499Modestobacter marinus, complete genomeDNA primase6e-47189
NC_019673:1988853:2027358202735820317464389Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein2e-45183
NC_008697:118859:1188591188591247625904Nocardioides sp. JS614 plasmid pNOCA01, complete sequenceDNA primase catalytic core, N-terminal domain3e-44180
NC_013757:780835:7808357808357863455511Geodermatophilus obscurus DSM 43160, complete genomeTrwC relaxase3e-44180
NC_008146:1535827:1553403155340315579744572Mycobacterium sp. MCS, complete genomeATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein4e-43176
NC_008705:1557711:1557711155771115622824572Mycobacterium sp. KMS, complete genomeATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like protein4e-43176
NC_008726:3968222:3968222396822239740805859Mycobacterium vanbaalenii PYR-1, complete genomeATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like1e-42174
NC_009338:2925286:2944475294447529503425868Mycobacterium gilvum PYR-GCK chromosome, complete genomeexonuclease V subunit alpha4e-42173
NC_013131:10370765:1038668610386686103908464161Catenulispora acidiphila DSM 44928, complete genomeTrwC relaxase4e-42173
NC_017955:3057592:3092495309249530980295535Modestobacter marinus, complete genomeDNA primase1e-40168
NC_015671:557720:5632625632625661532892Cellvibrio gilvus ATCC 13127 chromosome, complete genomeTrwC relaxase2e-39164
NC_016943:1422926:1442885144288514483835499Blastococcus saxobsidens DD2, complete genomeDNA primase2e-37157
NC_016943:1442885:1442885144288514483835499Blastococcus saxobsidens DD2, complete genomeDNA primase2e-37157
NC_016887:3160000:3164447316444731704255979Nocardia cyriacigeorgica GUH-2, complete genomehypothetical protein7e-33142
NC_013729:2258582:2280446228044622851314686Kribbella flavida DSM 17836, complete genomeTrwC relaxase9e-31135
NC_018681:5551000:5551247555124755572405994Nocardia brasiliensis ATCC 700358 chromosome, complete genomehypothetical protein6e-30132
NC_014158:233733:2645282645282674012874Tsukamurella paurometabola DSM 20162 chromosome, complete genomeTrwC relaxase1e-26121
NC_014550:3316115:3319383331938333220312649Arthrobacter arilaitensis Re117, complete genome2e-24114
NC_008699:1816392:1829796182979618323962601Nocardioides sp. JS614, complete genomeATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like2e-22108
NC_009445:6424000:6443614644361464466253012Bradyrhizobium sp. ORS 278 chromosome, complete genomeconjugal transfer relaxase TraA2e-22107
NC_009445:838281:8382818382818412923012Bradyrhizobium sp. ORS 278 chromosome, complete genomeconjugal transfer relaxase TraA6e-22106
NC_013714:1048783:1058087105808710622714185Bifidobacterium dentium Bd1, complete genomeTrwC relaxase9e-22105
NC_007925:138927:1633911633911664953105Rhodopseudomonas palustris BisB18, complete genomeMobA/MobL protein9e-22105
NC_009720:2945655:2945655294565529485852931Xanthobacter autotrophicus Py2, complete genomeconjugal transfer relaxase TraA9e-22105
NC_009720:251703:2737272737272766572931Xanthobacter autotrophicus Py2, complete genomeconjugal transfer relaxase TraA9e-22105
NC_008435:1131242:1160526116052611635463021Rhodopseudomonas palustris BisA53, complete genomeMobA/MobL protein8e-22105
NC_007958:4371125:4393639439363943967583120Rhodopseudomonas palustris BisB5, complete genomeMobA/MobL protein6e-22105
NC_010338:359940:3722873722873751452859Caulobacter sp. K31, complete genomeTi-type conjugative transfer relaxase TraA4e-21103
NC_009445:1316000:1316372131637213193262955Bradyrhizobium sp. ORS 278 chromosome, complete genomeconjugal transfer relaxase TraA5e-21102
NC_008699:1132790:1161255116125511638732619Nocardioides sp. JS614, complete genomeATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member-like5e-21102
NC_007925:1085500:1087177108717710902813105Rhodopseudomonas palustris BisB18, complete genomeMobA/MobL protein2e-20101
NC_010338:1216385:1217970121797012208282859Caulobacter sp. K31, complete genomeTi-type conjugative transfer relaxase TraA4e-20100
NC_002678:763808:7856497856497886963048Mesorhizobium loti MAFF303099, complete genomeprobable conjugal transfer protein traA6e-2099.4
NC_014217:2760898:2762803276280327657602958Starkeya novella DSM 506 chromosome, complete genomeTi-type conjugative transfer relaxase TraA6e-1996.3
NC_015675:5607297:5632354563235456354013048Mesorhizobium opportunistum WSM2075 chromosome, complete genomeTi-type conjugative transfer relaxase TraA7e-1995.9
NC_014217:2020737:2020737202073720236942958Starkeya novella DSM 506 chromosome, complete genomeTi-type conjugative transfer relaxase TraA3e-1894
NC_009720:464078:4822914822914852482958Xanthobacter autotrophicus Py2, complete genomeconjugal transfer relaxase TraA3e-1894
NC_015675:4565500:4576462457646245795093048Mesorhizobium opportunistum WSM2075 chromosome, complete genomeTi-type conjugative transfer relaxase TraA5e-1893.2
NC_011991:65368:6536865368694384071Agrobacterium vitis S4 plasmid pAtS4b, complete sequenceTi-type conjugative transfer relaxase TraA9e-1789
NC_013757:21245:2124521245240252781Geodermatophilus obscurus DSM 43160, complete genomeTrwC relaxase5e-1686.7
NC_009921:1611132:1633885163388516385344650Frankia sp. EAN1pec, complete genomeTrwC relaxase2e-1584.7
NC_014006:3124818:3167502316750231703452844Sphingobium japonicum UT26S chromosome 1, complete genomeconjugal transfer protein TraA2e-1584.3
NC_015508:296856:2968562968563006473792Agrobacterium sp. H13-3 chromosome linear, complete sequenceConjugal transfer protein traA7e-1582.8
NC_014550:3316115:3316115331611533186702556Arthrobacter arilaitensis Re117, complete genome2e-1481.3
NC_013757:900500:9140649140649176903627Geodermatophilus obscurus DSM 43160, complete genomeTrwC relaxase7e-1375.9
NC_016943:4194002:4194002419400241976853684Blastococcus saxobsidens DD2, complete genomeconjugative relaxase TrwC8e-1375.9
NC_013169:805124:8161218161218196033483Kytococcus sedentarius DSM 20547, complete genomeTrwC relaxase1e-1172
NC_012796:1600600:1609788160978816126312844Desulfovibrio magneticus RS-1, complete genomeconjugal transfer protein TraA3e-1170.5
NC_016943:1956719:1971062197106219746853624Blastococcus saxobsidens DD2, complete genomeconjugative relaxase TrwC4e-1170.5
NC_014816:1592799:1592799159279915960233225Asticcacaulis excentricus CB 48 chromosome 1, complete sequenceti-type conjugative transfer relaxase traa7e-1169.3
NC_007575:1694877:1701208170120817045463339Sulfurimonas denitrificans DSM 1251, complete genomeexonuclease V subunit alpha9e-1168.9
NC_010943:3069082:3094419309441930971992781Stenotrophomonas maltophilia K279a, complete genomeputative conjugal transfer protein TraA5e-1066.6
NC_016943:21364:2136421364249903627Blastococcus saxobsidens DD2, complete genomeconjugative relaxase TrwC5e-1066.6
NC_014666:8459724:8473764847376484785034740Frankia sp. EuI1c chromosome, complete genomeTrwC relaxase1e-0965.5
NC_007802:3252300:327506632750663275869804Jannaschia sp. CCS1, complete genomeconjugal transfer protein traA2e-0964.3
NC_014819:25765:4311743117462603144Asticcacaulis excentricus CB 48 plasmid pASTEX02, completeconjugative relaxase domain protein9e-0962.4
NC_010793:1811401:1869177186917718715432367Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraA4e-0860.5
NC_008278:6885254:6885254688525468896694416Frankia alni ACN14a, complete genomehypothetical protein; Putative conjugal transfer protein traA5e-0860.1
NC_010793:1158279:1162791116279111651962406Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraA4e-0860.1
NC_013757:1499643:1501336150133615050073672Geodermatophilus obscurus DSM 43160, complete genomeTrwC relaxase4e-0860.1
NC_014394:2577949:2590285259028525926032319Gallionella capsiferriformans ES-2 chromosome, complete genomeAAA ATPase7e-0859.3
NC_015562:1413264:1422784142278414260893306Methanotorris igneus Kol 5 chromosome, complete genomeexodeoxyribonuclease V1e-0758.9
NC_010606:25090:2872928729308792151Acinetobacter baumannii ACICU plasmid pACICU2, complete sequenceTrwC protein2e-0758.2
NC_011916:467106:4887684887684915782811Caulobacter crescentus NA1000 chromosome, complete genomeDNA relaxase/conjugal transfer nickase-helicase TrwC2e-0758.2
NC_009484:2660048:2674385267438526771562772Acidiphilium cryptum JF-5 chromosome, complete genomeexonuclease V subunit alpha2e-0757.8
NC_010793:1922000:1933705193370519347961092Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraA3e-0757
NC_010793:1468849:1475436147543614782402805Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraA5e-0756.6
NC_016631:3917253:3931643393164339343962754Granulicella mallensis MP5ACTX8 chromosome, complete genomeconjugative relaxase domain-containing protein9e-0755.8
NC_010793:1695716:1698219169821917002312013Orientia tsutsugamushi str. Ikeda, complete genomeputative conjugative transfer protein TraA1e-0655.5
NC_015573:776209:8021148021148046932580Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomehypothetical protein2e-0655.1
NC_011296:281930:2901722901722957035532Thermodesulfovibrio yellowstonii DSM 11347, complete genomehypothetical protein2e-0654.7
NC_008740:2563278:2574464257446425767072244Marinobacter aquaeolei VT8, complete genomeAAA ATPase4e-0653.5