Pre_GI: BLASTP Hits

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Query: NC_006085:1859191:1873290 Propionibacterium acnes KPA171202, complete genome

Start: 1873290, End: 1873976, Length: 687

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:1799521:181605818160581816810753Propionibacterium acnes TypeIA2 P.acn33 chromosome, completehypothetical protein5e-118423
NC_016512:1810625:182459218245921825344753Propionibacterium acnes TypeIA2 P.acn17 chromosome, completehypothetical protein5e-118423
NC_016511:1811171:182516618251661825918753Propionibacterium acnes TypeIA2 P.acn31 chromosome, completehypothetical protein5e-118423
NC_014039:1813205:182724118272411827993753Propionibacterium acnes SK137 chromosome, complete genomehypothetical protein5e-118423