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Query: NC_006085:1859191:1870658 Propionibacterium acnes KPA171202, complete genome

Start: 1870658, End: 1871059, Length: 402

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014039:1813205:182467818246781825190513Propionibacterium acnes SK137 chromosome, complete genomehydrolase, NUDIX family1e-60231
NC_016516:1799521:181349518134951813926432Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeNUDIX family hydrolase1e-60231
NC_016511:1811171:182260318226031823034432Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeNUDIX family hydrolase1e-60231
NC_016512:1810625:182202918220291822421393Propionibacterium acnes TypeIA2 P.acn17 chromosome, completeNUDIX family hydrolase4e-59226
NC_018750:770500:790424790424790906483Streptomyces venezuelae ATCC 10712, complete genomeputative MutT or NUDIX-family protein8e-2199
NC_012815:1357003:135859813585981359125528Bifidobacterium animalis subsp. lactis DSM 10140, complete genomehypothetical protein2e-1994.4
NC_012814:1357070:135866513586651359192528Bifidobacterium animalis subsp. lactis Bl-04, complete genomehypothetical protein2e-1994.4
NC_011835:965977:967572967572968099528Bifidobacterium animalis subsp. lactis AD011 chromosome, completeNudix hydrolase family protein2e-1994.4
NC_017216:1356930:135852513585251359052528Bifidobacterium animalis subsp. lactis BLC1, complete genomehydrolase, NUDIX family2e-1994.4
NC_017217:1362573:136416813641681364695528Bifidobacterium animalis subsp. lactis V9 chromosome, completehypothetical protein2e-1994.4
NC_017214:54558:561655616556794630Bifidobacterium animalis subsp. lactis BB-12 chromosome, completephosphohydrolase3e-1994
NC_017215:1361822:136342913634291364058630Bifidobacterium animalis subsp. lactis CNCM I-2494 chromosome,Hydrolase acting on acid anhydrides in phosphorous-containing anhydrides3e-1994
NC_018750:6132619:616128261612826161770489Streptomyces venezuelae ATCC 10712, complete genomeMutT or NUDIX family protein3e-1890.5
NC_015588:2939747:295787729578772958374498Isoptericola variabilis 225 chromosome, complete genomeNUDIX hydrolase1e-1065.1
NC_009725:496443:5486775486775499121236Bacillus amyloliquefaciens FZB42, complete genomehypothetical protein3e-1063.5
NC_020410:495184:5312675312675325051239Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completeUncharacterized 45.4 kDa protein in thiaminase I 5'region (Protein nagD homolog)4e-1063.5
NC_019897:1224798:124622312462231246681459Thermobacillus composti KWC4 chromosome, complete genomeZn-finger containing NTP pyrophosphohydrolase2e-0857.4
NC_015944:384119:3970483970483982771230Haloarcula hispanica ATCC 33960 plasmid pHH400, complete sequenceputative sugar phosphatase of HAD superfamily3e-0857
NC_007777:135222:161702161702162172471Frankia sp. CcI3, complete genomeNUDIX hydrolase1e-0755.1
NC_008062:81338:872898728987750462Burkholderia cenocepacia AU 1054 chromosome 3, complete sequenceNUDIX hydrolase3e-0753.9
NC_008544:55451:651086510865539432Burkholderia cenocepacia HI2424 chromosome 3, complete sequenceNUDIX hydrolase3e-0753.9
NC_014414:1140357:118132411813241181785462Parvularcula bermudensis HTCC2503 chromosome, complete genomeNUDIX hydrolase1e-0652