Pre_GI: BLASTP Hits

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Query: NC_006085:1859191:1859191 Propionibacterium acnes KPA171202, complete genome

Start: 1859191, End: 1860030, Length: 840

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:1799521:180208118020811802920840Propionibacterium acnes TypeIA2 P.acn33 chromosome, completebifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor2e-140498
NC_016512:1810625:181062518106251811464840Propionibacterium acnes TypeIA2 P.acn17 chromosome, completebifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor2e-140498
NC_016511:1811171:181117118111711812010840Propionibacterium acnes TypeIA2 P.acn31 chromosome, completebifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor2e-140498
NC_014039:1813205:181320518132051814044840Propionibacterium acnes SK137 chromosome, complete genomebiotin-(acetyl-CoA-carboxylase) ligase5e-139493
NC_017955:4746441:476219947621994763023825Modestobacter marinus, complete genomebiotin-(Acetyl-CoA-carboxylase) ligase4e-26118
NC_007530:1459412:146990314699031470883981Bacillus anthracis str. 'Ames Ancestor', complete genomebira bifunctional protein7e-1787.8
NC_005945:1459357:146985714698571470837981Bacillus anthracis str. Sterne, complete genomebirA bifunctional protein7e-1787.8
NC_011296:1542835:154283515428351543635801Thermodesulfovibrio yellowstonii DSM 11347, complete genomebiotin-[acetyl-CoA-carboxylase] ligase2e-1582.8
NC_014960:2111397:212663521266352127411777Anaerolinea thermophila UNI-1, complete genomebiotin--[acetyl-CoA-carboxylase] ligase2e-1582.8
NC_018664:2459994:248115824811582482144987Clostridium acidurici 9a chromosome, complete genomebifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA1e-1480.9
NC_014640:6745873:674587367458736746826954Achromobacter xylosoxidans A8 chromosome, complete genomebiotin-[acetyl-CoA-carboxylase] ligase2e-1479.7
NC_020207:2575808:259161325916132592581969Enterococcus faecium NRRL B-2354, complete genomeBiotin-protein ligase, Biotin operon repressor3e-1479.3
CU928160:4248621:426222742622274263192966Escherichia coli IAI1 chromosome, complete genomebifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and DNA-binding transcriptional repressor, bio-5'-AMP-binding2e-1376.6
NC_002516:4747154:478747747874774788415939Pseudomonas aeruginosa PAO1, complete genomebiotin--protein ligase2e-1376.6
NC_010468:4455201:445828244582824459247966Escherichia coli ATCC 8739, complete genomebifunctional BirA, biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase2e-1376.3
NC_009727:1001203:102432810243281025299972Coxiella burnetii Dugway 7E9-12, complete genomebifunctional protein birA2e-1376.3
NC_011528:767940:790159790159791130972Coxiella burnetii CbuK_Q154, complete genomebiotin operon repressor2e-1376.3
NC_009089:4140764:415845141584514159428978Clostridium difficile 630, complete genomeBirA bifunctional protein [includes: biotin operon repressor and biotin--[acetyl-CoA-carboxylase] synthetase3e-1375.9
NC_011750:4543135:455292745529274553892966Escherichia coli IAI39 chromosome, complete genomebiotin--protein ligase7e-1374.7
NC_014410:615992:636077636077637057981Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,biotin/acetyl-CoA-carboxylase ligase6e-1374.7
NC_010473:4256000:427080242708024271767966Escherichia coli str. K-12 substr. DH10B, complete genomebifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and DNA-binding transcriptional repressor, bio-5'-AMP-binding6e-1374.7
NC_000913:4159090:417110541711054172070966Escherichia coli K12, complete genomebiotin--protein ligase6e-1374.7
NC_011527:953442:976348976348977319972Coxiella burnetii CbuG_Q212, complete genomebiotin operon repressor8e-1374.3
NC_015709:1459838:146277014627701463555786Zymomonas mobilis subsp. pomaceae ATCC 29192 chromosome, completebiotin/acetyl-CoA-carboxylase ligase8e-1374.3
NC_007946:3683371:369106336910633692028966Escherichia coli UTI89, complete genomebifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor1e-1273.6
NC_009922:490500:500402500402501382981Alkaliphilus oremlandii OhILAs, complete genomebiotin--acetyl-CoA-carboxylase ligase2e-1273.2
NC_003198:3586000:359255035925503593512963Salmonella enterica subsp. enterica serovar Typhi str. CT18,biotin--protein ligase2e-1272.8
NC_006511:4119332:413132641313264132288963Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCbiotin--protein ligase2e-1272.8
NC_013316:4018451:403677340367734037750978Clostridium difficile R20291, complete genomeBirA bifunctional protein [includes: biotin operon repressor and biotin--[acetyl-CoA-carboxylase] synthetase3e-1272.4
NC_016931:773871:786570786570787382813Rickettsia massiliae str. AZT80 chromosome, complete genomebiotin-(acetyl-CoA carboxylase) ligase3e-1272.4
NC_016632:1637500:165877016587701659732963Serratia symbiotica str. 'Cinara cedri' chromosome, completebiotin--protein ligase6e-1271.6
NC_015381:4070968:407215440721544073068915Burkholderia gladioli BSR3 chromosome 1, complete sequencebiotin--acetyl-CoA-carboxylase ligase7e-1271.2
NC_015731:2950874:296098829609882961977990Nitrosomonas sp. Is79A3 chromosome, complete genomebiotin/acetyl-CoA-carboxylase ligase7e-1271.2
NC_010001:3369500:338309933830993384076978Clostridium phytofermentans ISDg, complete genomebiotin--acetyl-CoA-carboxylase ligase9e-1270.9
NC_007912:1173752:118056411805641181562999Saccharophagus degradans 2-40, complete genomeBiotin--(acetyl-CoA-carboxylase) ligase1e-1170.9
NC_016584:85543:880248802489004981Desulfosporosinus orientis DSM 765 chromosome, complete genomebiotin-(acetyl-CoA-carboxylase) ligase BirA1e-1170.9
NC_014393:4988127:500259050025905003393804Clostridium cellulovorans 743B chromosome, complete genomebiotin/acetyl-CoA-carboxylase ligase1e-1170.9
NC_020134:2832857:2855412285541228564221011Clostridium stercorarium subsp. stercorarium DSM 8532, completebifunctional protein biotin operon repressor/biotin--[acetyl-CoA-carboxylase] synthetase BirA4e-1168.9
NC_011184:2723000:272422527242252725184960Vibrio fischeri MJ11 chromosome I, complete sequencebiotin-(acetyl-CoA-carboxylase) ligase4e-1168.6
NC_013407:10953:126701267013395726Methanocaldococcus vulcanius M7, complete genomebiotin/acetyl-CoA-carboxylase ligase5e-1168.6
NC_000917:40111:733967339674295900Archaeoglobus fulgidus DSM 4304, complete genomebiotin operon repressor/biotin--[acetyl CoA carboxylase] ligase (birA)7e-1168.2
NC_005061:214168:218136218136218960825Candidatus Blochmannia floridanus, complete genomebifunctional protein: biotin operon repressor and biotin-[acetyl-CoA carboxylase] synthetase2e-1066.6
NC_014836:497350:5211065211065221161011Desulfurispirillum indicum S5 chromosome, complete genomebiotin/acetyl-CoA-carboxylase ligase8e-1064.7
NC_010981:1053533:106640010664001067236837Wolbachia pipientis, complete genomebiotin-[acetyl-coa-carboxylase] ligase9e-1064.3
NC_014655:1835848:183584818358481836597750Leadbetterella byssophila DSM 17132 chromosome, complete genomebiotin/acetyl-CoA-carboxylase ligase1e-0964.3
NC_007907:225948:231384231384232364981Desulfitobacterium hafniense Y51, complete genomehypothetical protein1e-0963.9
NC_015977:3324000:334446233444623345439978Roseburia hominis A2-183 chromosome, complete genomeputative transcriptional repressor of the biotin operon birA2e-0963.2
NC_008782:4229306:424624642462464247103858Acidovorax sp. JS42, complete genomebiotin--acetyl-CoA-carboxylase ligase2e-0963.2
NC_015172:775128:782332782332783330999Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomebiotin/acetyl-CoA-carboxylase ligase2e-0963.2
NC_016052:82358:878958789588854960Tetragenococcus halophilus NBRC 12172, complete genomeputative transcriptional regulator/biotin protein ligase3e-0962.8
NC_014408:462195:462195462195462980786Methanothermobacter marburgensis str. Marburg chromosome, completebiotin ligase4e-0962.4
NC_012416:979484:990745990745991617873Wolbachia sp. wRi, complete genomebiotin-[acetyl-coa-carboxylase] ligase, putative4e-0962
NC_011992:3550566:356662735666273567484858Acidovorax ebreus TPSY, complete genomebiotin/acetyl-CoA-carboxylase ligase7e-0961.2
NC_014909:219498:224807224807225577771Candidatus Blochmannia vafer str. BVAF chromosome, complete genomebiotin-(acetyl-CoA-carboxylase) synthetase8e-0961.2
NC_007645:6350079:636514663651466366033888Hahella chejuensis KCTC 2396, complete genomeBiotin-(acetyl-CoA carboxylase) ligase1e-0860.5
NC_016938:336000:340981340981341937957Melissococcus plutonius DAT561 chromosome 1, complete genomebiotin--protein ligase1e-0860.5
NC_013192:107672:127790127790128494705Leptotrichia buccalis DSM 1135, complete genomebiotin/acetyl-CoA-carboxylase ligase1e-0860.5
NC_009515:705911:726156726156727073918Methanobrevibacter smithii ATCC 35061, complete genomebiotin-[acetyl-CoA-carboxylase] ligase/biotin operon regulator bifunctional protein, BirA2e-0860.1
NC_014774:1019273:102246110224611023219759Candidatus Liberibacter solanacearum CLso-ZC1 chromosome, completebirA bifunctional protein2e-0860.1
NC_021150:582011:586093586093587085993Azotobacter vinelandii CA6, complete genomebiotin--protein ligase2e-0860.1
NC_012560:582011:586093586093587085993Azotobacter vinelandii DJ, complete genomeBiotin--acetyl-CoA-carboxylase ligase, bifunctional protein, BirA2e-0860.1
NC_019903:83857:909179091791897981Desulfitobacterium dichloroeliminans LMG P-21439 chromosome,biotin-(acetyl-CoA-carboxylase) ligase BirA2e-0860.1
NC_011126:163878:175669175669176382714Hydrogenobaculum sp. Y04AAS1, complete genomebiotin/acetyl-CoA-carboxylase ligase2e-0859.7
NC_007503:2098980:212529321252932126279987Carboxydothermus hydrogenoformans Z-2901, complete genomeBirA bifunctional protein4e-0858.5
NC_004113:1137754:114219511421951142899705Thermosynechococcus elongatus BP-1, complete genomeputative biotin acetyl-CoA-carboxylase synthetase5e-0858.5
NC_000868:133451:150138150138150851714Pyrococcus abyssi GE5, complete genomebiotin--protein ligase8e-0857.8
NC_014109:393500:412673412673413329657Candidatus Riesia pediculicola USDA chromosome, complete genomebiotin-[acetyl-CoA-carboxylase] ligase1e-0757.4
NC_014297:1282302:130322413032241304147924Halalkalicoccus jeotgali B3 chromosome, complete genomebiotin--[acetyl-CoA-carboxylase] ligase2e-0757
NC_017514:96911:1206251206251224031779Neisseria meningitidis M01-240149 chromosome, complete genomebiotin-(acetyl-CoA-carboxylase) ligase/transcriptional activator, Baf family2e-0757
NC_015964:1389628:139437213943721395286915Haemophilus parainfluenzae T3T1, complete genomebifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase/ DNA-binding transcriptional repressor, bio-5'-AMP-binding1e-0757
NC_015571:722815:738618738618739391774Porphyromonas gingivalis TDC60, complete genomebiotin--acetyl-CoA-carboxylase ligase1e-0757
NC_007797:914500:930013930013930738726Anaplasma phagocytophilum HZ, complete genomebiotin--acetyl-CoA-carboxylase ligase1e-0757
NC_010080:1885677:189390018939001894889990Lactobacillus helveticus DPC 4571, complete genomeBiotin--acetyl-CoA-carboxylase ligase7e-0754.7
NC_002978:918000:9305979305979316401044Wolbachia endosymbiont of Drosophila melanogaster, complete genomebiotin protein ligase, putative7e-0754.7
NC_015947:280095:283006283006283974969Burkholderia sp. JV3 chromosome, complete genomebiotin/acetyl-CoA-carboxylase ligase2e-0653.1
NC_018528:1932000:194260919426091943598990Lactobacillus helveticus R0052 chromosome, complete genomebiotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor2e-0653.1
NC_015602:1949610:195919919591991960188990Lactobacillus kefiranofaciens ZW3 chromosome, complete genomebiotin-[acetyl-CoA-carboxylase] ligase and biotin operon repressor2e-0653.1
NC_008789:942309:947661947661948638978Halorhodospira halophila SL1, complete genomebiotin--acetyl-CoA-carboxylase ligase2e-0652.8
NC_011295:1218792:122744012274401228045606Coprothermobacter proteolyticus DSM 5265, complete genomebiotin-[acetyl-CoA-carboxylase] ligase3e-0652.8
NC_015516:1801500:181219218121921813166975Melissococcus plutonius ATCC 35311, complete genomebiotin-protein ligase/ biotin operon repressor6e-0651.6