Pre_GI: BLASTP Hits

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Query: NC_005957:5091150:5105849 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Start: 5105849, End: 5106223, Length: 375

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:5079460:509412350941235094497375Bacillus cereus F837/76 chromosome, complete genomehypothetical protein2e-53207
NC_012581:5085915:510011951001195100493375Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein2e-53207
NC_011773:5144990:516016851601685160542375Bacillus cereus AH820 chromosome, complete genomehypothetical protein2e-53207
NC_012472:5126186:514083951408395141213375Bacillus cereus 03BB102, complete genomehypothetical protein2e-53207
NC_014335:5038601:505354350535435053917375Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-53207
NC_008600:5113765:512842851284285128802375Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein2e-53207
NC_011772:5222917:524141352414135241787375Bacillus cereus G9842, complete genomehypothetical protein2e-51200
NC_017208:5339331:535473153547315355105375Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein7e-51198
NC_006274:5155395:517029551702955170669375Bacillus cereus E33L, complete genomegroup-specific protein2e-50197
NC_011969:5063283:507811750781175078491375Bacillus cereus Q1 chromosome, complete genomegroup-specific protein3e-49193
NC_012491:4231469:423856942385694238982414Brevibacillus brevis NBRC 100599, complete genomehypothetical protein2e-1064.7
NC_007103:230872:273018273018273437420Bacillus cereus E33L plasmid pE33L466, complete sequencehypothetical protein4e-0960.1