Pre_GI: BLASTP Hits

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Query: NC_005957:5037499:5057084 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Start: 5057084, End: 5057668, Length: 585

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:5009320:504562350456235046138516Bacillus cereus F837/76 chromosome, complete genomehypothetical protein4e-94343
NC_017200:5149528:516987351698735170388516Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein8e-94342
NC_003909:4996783:503077650307765031291516Bacillus cereus ATCC 10987, complete genomehypothetical protein8e-94342
NC_016935:7426389:744061474406147441147534Paenibacillus mucilaginosus 3016 chromosome, complete genomehypothetical protein2e-24112
NC_015690:7334786:734852573485257349058534Paenibacillus mucilaginosus KNP414 chromosome, complete genomehypothetical protein2e-24112
NC_014628:168994:174975174975175496522Paenibacillus polymyxa SC2 plasmid pSC2, complete sequencehypothetical protein2e-1582