Pre_GI: BLASTP Hits

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Query: NC_005957:4244019:4246421 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Start: 4246421, End: 4246966, Length: 546

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_006274:4295730:430127443012744301819546Bacillus cereus E33L, complete genomerod shape-determining protein3e-91333
NC_014335:4181710:418754941875494188094546Bacillus cereus biovar anthracis str. CI chromosome, completerod shape-determining protein1e-90331
NC_012659:4252000:425686142568614257406546Bacillus anthracis str. A0248, complete genomerod shape-determining protein MreD3e-90330
NC_007530:4251773:425696142569614257506546Bacillus anthracis str. 'Ames Ancestor', complete genomerod shape-determining protein mred3e-90330
NC_012472:4255729:426156842615684262113546Bacillus cereus 03BB102, complete genomerod shape-determining protein MreD3e-90330
NC_003997:4252000:425683442568344257379546Bacillus anthracis str. Ames, complete genomerod shape-determining protein MreD3e-90330
NC_005945:4251789:425733342573334257878546Bacillus anthracis str. Sterne, complete genomerod shape-determining protein MreD3e-90330
NC_014171:4317520:431752043175204318065546Bacillus thuringiensis BMB171 chromosome, complete genomerod shape-determining protein mreD5e-88323
NC_017200:4267408:426981042698104270355546Bacillus thuringiensis serovar finitimus YBT-020 chromosome,rod shape-determining protein MreD4e-87320
NC_016771:4195888:420059942005994201144546Bacillus cereus NC7401, complete genomerod shape-determining protein MreD4e-87320
NC_011969:4140000:414474041447404145285546Bacillus cereus Q1 chromosome, complete genomerod shape-determining protein mred4e-87320
NC_011658:4243561:424681642468164247361546Bacillus cereus AH187 chromosome, complete genomerod shape-determining protein MreD4e-87320
NC_003909:4209385:421010742101074210652546Bacillus cereus ATCC 10987, complete genomerod shape-determining protein MreD4e-87320
NC_010184:4287999:429270642927064293251546Bacillus weihenstephanensis KBAB4, complete genomeRod shape-determining protein MreD8e-85312