Pre_GI: BLASTP Hits

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Query: NC_005957:4169610:4171326 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Start: 4171326, End: 4171964, Length: 639

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017200:4191963:419267341926734193311639Bacillus thuringiensis serovar finitimus YBT-020 chromosome,hypothetical protein3e-122437
NC_011969:4065460:406831340683134068951639Bacillus cereus Q1 chromosome, complete genomedimethyladenosine transferase3e-122437
NC_011658:4171237:417295341729534173591639Bacillus cereus AH187 chromosome, complete genomehypothetical protein3e-122437
NC_007530:4176462:418217841821784182816639Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein3e-122437
NC_014335:4113154:411386441138644114502639Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein4e-121433
NC_015275:4577642:4595596459559645971731578Clostridium lentocellum DSM 5427 chromosome, complete genomeCysteine synthase1e-39162
NC_000868:378130:389752389752390369618Pyrococcus abyssi GE5, complete genomemethlytransferase5e-26117
NC_016048:3947663:397372939737293974352624Oscillibacter valericigenes Sjm18-20, complete genomeputative methyltransferase5e-1581.3
NC_007681:696252:697984697984698661678Methanosphaera stadtmanae DSM 3091, complete genomehypothetical protein5e-0857.8
NC_007355:544796:558137558137558889753Methanosarcina barkeri str. fusaro chromosome 1, complete sequenceubiquinone/menaquinone biosynthesis methyltransferase1e-0756.6
NC_013730:3137391:315058331505833151362780Spirosoma linguale DSM 74, complete genomeMethyltransferase type 112e-0756.2
NC_015574:2322811:232662423266242327301678Methanobacterium sp. SWAN-1 chromosome, complete genometype 12 methyltransferase3e-0755.1
NC_018681:1021063:104027410402741040933660Nocardia brasiliensis ATCC 700358 chromosome, complete genometype 11 methyltransferase5e-0754.7
NC_014624:2996377:300986630098663010609744Eubacterium limosum KIST612 chromosome, complete genomehypothetical protein5e-0754.7
NC_017904:3113000:312282331228233123479657Mycobacterium sp. MOTT36Y chromosome, complete genomemethyltransferase7e-0753.9
NC_016641:1530905:154436315443631545133771Paenibacillus terrae HPL-003 chromosome, complete genomehypothetical protein3e-0651.6
NC_015277:2702056:271979127197912720465675Sphingobacterium sp. 21 chromosome, complete genomeMethyltransferase type 127e-0650.8