Pre_GI: BLASTP Hits

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Query: NC_005957:2196000:2201325 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Start: 2201325, End: 2201615, Length: 291

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:2175867:218169321816932181983291Bacillus anthracis str. A0248, complete genomehypothetical protein1e-49194
NC_011773:2239753:224562422456242245914291Bacillus cereus AH820 chromosome, complete genomehypothetical protein1e-49194
NC_012472:2240000:224544222454422245732291Bacillus cereus 03BB102, complete genomehypothetical protein1e-49194
NC_005945:2175871:218177521817752182065291Bacillus anthracis str. Sterne, complete genomehypothetical protein1e-49194
NC_003997:2175843:218166921816692181959291Bacillus anthracis str. Ames, complete genomehypothetical protein1e-49194
NC_007530:2175967:218179321817932182083291Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-49194
NC_014335:2151404:215796221579622158252291Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein7e-49192
NC_014171:2177353:218418021841802184470291Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein2e-44177
NC_011725:2206000:221203622120362212326291Bacillus cereus B4264 chromosome, complete genomehypothetical protein2e-44177
NC_011658:2275864:228111522811152281405291Bacillus cereus AH187 chromosome, complete genomehypothetical protein3e-44176
NC_005945:3359598:337390633739063374196291Bacillus anthracis str. Sterne, complete genomehypothetical protein6e-1786.3
NC_011772:2166000:217176421717642171892129Bacillus cereus G9842, complete genomehypothetical protein3e-1580.1
NC_013205:526281:560154560154560462309Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446,HesB/YadR/YfhF-family protein5e-0960.1