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Query: NC_005956:1888500 Bartonella henselae str. Houston-1, complete genome

Start: 1888500, End: 1906099, Length: 17600

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_005955:15408381540838156386123024Bartonella quintana str. Toulouse, complete genome08699BLASTN svgBLASTP svg
NC_012846:22992822299282232146122180Bartonella grahamii as4aup, complete genome04754BLASTN svgBLASTP svg
NC_008783:29972*299725377323802Bartonella bacilliformis KC583, complete genome01372BLASTN svgBLASTP svg
NC_005956:1648000*1648000167344625447Bartonella henselae str. Houston-1, complete genome1e-23119BLASTN svgBLASTP svg
NC_012846:92957092957095327323704Bartonella grahamii as4aup, complete genome9e-1589.7BLASTN svgBLASTP svg
NC_005956:1455496*1455496147609920604Bartonella henselae str. Houston-1, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_010161:1179000*1179000119858119582Bartonella tribocorum CIP 105476, complete genome3e-1177.8BLASTN svgBLASTP svg
NC_010161:1501758*1501758153237830621Bartonella tribocorum CIP 105476, complete genome5e-1073.8BLASTN svgBLASTP svg
NC_005956:1402500*1402500142514422645Bartonella henselae str. Houston-1, complete genome5e-1073.8BLASTN svgBLASTP svg
NC_010161:23811952381195240409922905Bartonella tribocorum CIP 105476, complete genome8e-0969.9BLASTN svgBLASTP svg
NC_012846:986877986877102533738461Bartonella grahamii as4aup, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_013209:2759160*2759160277974720588Acetobacter pasteurianus IFO 3283-01, complete genome2e-0661.9BLASTN svgBLASTP svg