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Query: NC_005956:1111500 Bartonella henselae str. Houston-1, complete genome

Start: 1111500, End: 1129445, Length: 17946

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010161:1501758*1501758153237830621Bartonella tribocorum CIP 105476, complete genome02573BLASTN svgBLASTP svg
NC_007645:6327428*6327428635426926842Hahella chejuensis KCTC 2396, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_009053:89596589596592080824844Actinobacillus pleuropneumoniae L20, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_010611:24083924083927225731419Acinetobacter baumannii ACICU, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_010410:36068263606826369540988584Acinetobacter baumannii AYE, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_011146:3537546*3537546356804230497Geobacter bemidjiensis Bem, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_004757:2657490*2657490268195024461Nitrosomonas europaea ATCC 19718, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_005061:52470452470454944624743Candidatus Blochmannia floridanus, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_009879:260000*26000028209922100Rickettsia canadensis str. McKiel, complete genome3e-0867.9BLASTN svgBLASTP svg
NC_013170:1*11459914599Cryptobacterium curtum DSM 15641, complete genome5e-0763.9BLASTN svgBLASTP svg
NC_015460:26024162602416262318920774Gallibacterium anatis UMN179 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_010658:42573104257310427618618877Shigella boydii CDC 3083-94, complete genome8e-0660BLASTN svgBLASTP svg
NC_007613:41197714119771413859918829Shigella boydii Sb227, complete genome8e-0660BLASTN svgBLASTP svg
NC_006449:1572000*1572000159415422155Streptococcus thermophilus CNRZ1066, complete genome8e-0660BLASTN svgBLASTP svg
NC_006448:1568000*1568000159009922100Streptococcus thermophilus LMG 18311, complete genome8e-0660BLASTN svgBLASTP svg