Query: NC_005956:1111500 Bartonella henselae str. Houston-1, complete genome
Start: 1111500, End: 1129445, Length: 17946
Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_010161:1501758* | 1501758 | 1532378 | 30621 | Bartonella tribocorum CIP 105476, complete genome | 0 | 2573 | BLASTN svg | BLASTP svg |
NC_007645:6327428* | 6327428 | 6354269 | 26842 | Hahella chejuensis KCTC 2396, complete genome | 2e-16 | 95.6 | BLASTN svg | BLASTP svg |
NC_009053:895965 | 895965 | 920808 | 24844 | Actinobacillus pleuropneumoniae L20, complete genome | 4e-14 | 87.7 | BLASTN svg | BLASTP svg |
NC_010611:240839 | 240839 | 272257 | 31419 | Acinetobacter baumannii ACICU, complete genome | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_010410:3606826 | 3606826 | 3695409 | 88584 | Acinetobacter baumannii AYE, complete genome | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_011146:3537546* | 3537546 | 3568042 | 30497 | Geobacter bemidjiensis Bem, complete genome | 2e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_004757:2657490* | 2657490 | 2681950 | 24461 | Nitrosomonas europaea ATCC 19718, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_005061:524704 | 524704 | 549446 | 24743 | Candidatus Blochmannia floridanus, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_009879:260000* | 260000 | 282099 | 22100 | Rickettsia canadensis str. McKiel, complete genome | 3e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_013170:1* | 1 | 14599 | 14599 | Cryptobacterium curtum DSM 15641, complete genome | 5e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_015460:2602416 | 2602416 | 2623189 | 20774 | Gallibacterium anatis UMN179 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_010658:4257310 | 4257310 | 4276186 | 18877 | Shigella boydii CDC 3083-94, complete genome | 8e-06 | 60 | BLASTN svg | BLASTP svg |
NC_007613:4119771 | 4119771 | 4138599 | 18829 | Shigella boydii Sb227, complete genome | 8e-06 | 60 | BLASTN svg | BLASTP svg |
NC_006449:1572000* | 1572000 | 1594154 | 22155 | Streptococcus thermophilus CNRZ1066, complete genome | 8e-06 | 60 | BLASTN svg | BLASTP svg |
NC_006448:1568000* | 1568000 | 1590099 | 22100 | Streptococcus thermophilus LMG 18311, complete genome | 8e-06 | 60 | BLASTN svg | BLASTP svg |