Pre_GI: BLASTP Hits

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Query: NC_005956:1888500:1888621 Bartonella henselae str. Houston-1, complete genome

Start: 1888621, End: 1889364, Length: 744

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005955:1540838:154083815408381541581744Bartonella quintana str. Toulouse, complete genomehypothetical protein6e-128456
NC_012846:2299282:229928222992822300031750Bartonella grahamii as4aup, complete genomeputative lipoprotein2e-123441
NC_008783:29972:467644676447507744Bartonella bacilliformis KC583, complete genomeputative lipoprotein3e-99361
NC_011985:3380842:3380842338084233821461305Agrobacterium radiobacter K84 chromosome 1, complete genomehypothetical protein4e-71268
NC_011894:6001144:6014538601453860156741137Methylobacterium nodulans ORS 2060, complete genomehypothetical protein1e-66252
NC_011757:1091486:1105718110571811067911074Methylobacterium chloromethanicum CM4, complete genomeprotein of unknown function DUF9496e-62237
NC_012988:1130227:1146046114604611471191074Methylobacterium extorquens DM4, complete genomehypothetical protein6e-62237
NC_011768:3854455:386705138670513867770720Desulfatibacillum alkenivorans AK-01, complete genomeErfK/YbiS/YcfS/YnhG family protein6e-49194
NC_002695:261235:283032283032283772741Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein1e-48192
NC_007946:258747:277563277563278303741Escherichia coli UTI89, complete genomeprobable membrane protein1e-48192
NC_008253:257059:276888276888277628741Escherichia coli 536, complete genomeputative periplasmic protein1e-48192
NC_007384:278810:295212295212295952741Shigella sonnei Ss046, complete genomehypothetical protein1e-48192
NC_011751:256830:279780279780280520741Escherichia coli UMN026 chromosome, complete genomehypothetical protein1e-48192
NC_008563:258725:277542277542278282741Escherichia coli APEC O1, complete genomehypothetical protein1e-48192
NC_011742:258746:277562277562278302741Escherichia coli S88 chromosome, complete genomehypothetical protein1e-48192
NC_011745:258727:279461279461280201741Escherichia coli ED1a chromosome, complete genomehypothetical protein1e-48192
NC_016831:2667561:266685026668502667590741Salmonella enterica subsp. enterica serovar Gallinarum/pullorumhypothetical protein2e-47189
NC_020260:3004500:302582030258203026557738Cronobacter sakazakii Sp291, complete genomehypothetical protein2e-46186
NC_004547:3866439:389166838916683892402735Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein3e-46185
NC_009708:3542336:356586335658633566603741Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein1e-45183
NC_017154:3576256:359978335997833600523741Yersinia pestis D106004 chromosome, complete genomehypothetical protein5e-45181
NC_014029:3633955:365748236574823658222741Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-45181
NC_012997:2254000:227630522763052276820516Teredinibacter turnerae T7901, complete genomehypothetical protein3e-43175
NC_019908:121178:142756142756143484729Brachyspira pilosicoli P43/6/78 chromosome, complete genomehypothetical protein2e-33142
NC_018604:1943561:195639219563921957120729Brachyspira pilosicoli WesB complete genomeErfK/YbiS/YcfS/YnhG family protein5e-33141
NC_014330:505412:521281521281522009729Brachyspira pilosicoli 95/1000 chromosome, complete genomehypothetical protein8e-33140
NC_018607:921923:943036943036943764729Brachyspira pilosicoli B2904 chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-32139
NC_012225:345704:367331367331368032702Brachyspira hyodysenteriae WA1, complete genomehypothetical protein3e-30131
NC_014150:446359:466658466658467401744Brachyspira murdochii DSM 12563 chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-28125
NC_002977:652481:671682671682672560879Methylococcus capsulatus str. Bath, complete genomehypothetical protein1e-1790.5
NC_016745:1892500:190619119061911906841651Oceanimonas sp. GK1 chromosome, complete genomehypothetical protein5e-1788.2
NC_009483:2489000:2515639251563925166521014Geobacter uraniireducens Rf4 chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-0756.6
NC_011146:4505821:452754245275424528537996Geobacter bemidjiensis Bem, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-0756.2
NC_012918:4648220:466296346629634663958996Geobacter sp. M21 chromosome, complete genomeErfK/YbiS/YcfS/YnhG family protein2e-0756.2
NC_002939:173833:194938194938195867930Geobacter sulfurreducens PCA, complete genomelipoprotein, putative7e-0754.3