Pre_GI: BLASTP Hits

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Query: NC_005956:1521736:1532694 Bartonella henselae str. Houston-1, complete genome

Start: 1532694, End: 1534088, Length: 1395

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005955:1259393:1265556126555612670581503Bartonella quintana str. Toulouse, complete genomehypothetical protein1e-129463
NC_005955:1259393:1269465126946512712461782Bartonella quintana str. Toulouse, complete genomehypothetical protein6e-87321
NC_005955:1259393:1267412126741212691571746Bartonella quintana str. Toulouse, complete genomehypothetical protein9e-76284
NC_010161:1811000:1819541181954118208331293Bartonella tribocorum CIP 105476, complete genomehypothetical protein3e-67256
NC_020301:1449616:1461033146103314622501218Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeBep protein4e-67255
NC_012846:1679184:1688666168866616899461281Bartonella grahamii as4aup, complete genomeBepE protein2e-62240
NC_005956:1521736:1534424153442415369282505Bartonella henselae str. Houston-1, complete genomehypothetical protein2e-62240
NC_020301:1449616:1462532146253214642051674Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeBep protein4e-59229
NC_012846:1679184:1690157169015716919831827Bartonella grahamii as4aup, complete genomeBepF protein2e-45183
NC_010161:1811000:1821138182113818231051968Bartonella tribocorum CIP 105476, complete genomehypothetical protein4e-45182
NC_012846:1679184:168751016875101688340831Bartonella grahamii as4aup, complete genomeBepH protein5e-42172
NC_010161:1811000:181837018183701819188819Bartonella tribocorum CIP 105476, complete genomeBepH protein2e-36154
NC_005956:1521736:1537113153711315402443132Bartonella henselae str. Houston-1, complete genomehypothetical protein2e-34146
NC_012846:1679184:1692301169230116955103210Bartonella grahamii as4aup, complete genomeBepI protein3e-24113
NC_005956:1521736:1528692152869215302901599Bartonella henselae str. Houston-1, complete genomePutative cell filamentation protein2e-22107
NC_010161:1811000:1823441182344118258132373Bartonella tribocorum CIP 105476, complete genomeBepI protein6e-22105
NC_020301:1449616:1465240146524014664121173Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeBep protein6e-22105
NC_020301:1449616:1457313145731314589111599Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeBep protein5e-2099.4
NC_005956:1521736:1530764153076415323681605Bartonella henselae str. Houston-1, complete genomehypothetical protein1e-1894.4
NC_005956:1521736:1521736152173615233701635Bartonella henselae str. Houston-1, complete genomePutative cell filamentation protein6e-1892.4
NC_020301:1449616:1459227145922714607111485Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeBep protein1e-1791.7
NC_020301:1449616:1452979145297914546071629Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeBep protein3e-1790.1
NC_012846:1679184:1684104168410416857021599Bartonella grahamii as4aup, complete genomeBepC protein1e-1688.2
NC_010161:1811000:1814544181454418161421599Bartonella tribocorum CIP 105476, complete genomehypothetical protein4e-1686.3
NC_012846:1679184:1686016168601616871851170Bartonella grahamii as4aup, complete genomeBepD protein1e-1584.7
NC_005955:1259393:1263630126363012652311602Bartonella quintana str. Toulouse, complete genomePutative cell filamentation protein1e-1584.7
NC_020301:1449616:1450976145097614526041629Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeBep protein2e-1584.3
NC_010161:1811000:1816452181645218180261575Bartonella tribocorum CIP 105476, complete genomehypothetical protein6e-1582.4
NC_012846:1679184:1679184167918416808181635Bartonella grahamii as4aup, complete genomeBepA protein1e-1481.6
NC_005955:1259393:1259393125939312609071515Bartonella quintana str. Toulouse, complete genome2e-1481.3
NC_005956:1521736:1525994152599415276221629Bartonella henselae str. Houston-1, complete genomehypothetical protein3e-1273.6