Pre_GI: BLASTP Hits

Some Help

Query: NC_005956:1111500:1111850 Bartonella henselae str. Houston-1, complete genome

Start: 1111850, End: 1113064, Length: 1215

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009720:5046861:5050055505005550512691215Xanthobacter autotrophicus Py2, complete genomeisocitrate dehydrogenase0712
NC_014817:142976:1469601469601481741215Asticcacaulis excentricus CB 48 chromosome 2, complete sequenceisocitrate dehydrogenase, nADP-dependent0698
NC_006087:2008000:2008100200810020093141215Leifsonia xyli subsp. xyli str. CTCB07, complete genomeisocitrate dehydrogenase6e-179627
NC_019673:8581000:8581737858173785829571221Saccharothrix espanaensis DSM 44229 complete genomeIsocitrate dehydrogenase [NADP]1e-176619
NC_013159:502928:5029285029285041511224Saccharomonospora viridis DSM 43017, complete genomeisocitrate dehydrogenase (NADP)1e-174613
NC_016887:1093609:1113573111357311147901218Nocardia cyriacigeorgica GUH-2, complete genomeisocitrate dehydrogenase (NADP-dependent), (Oxalosuccinate decarboxylase)1e-174612
NC_018664:3009166:3026314302631430275281215Clostridium acidurici 9a chromosome, complete genomeNADP-dependend isocitrate dehydrogenase Idh1e-123443
NC_011830:1623452:1623452162345216246631212Desulfitobacterium hafniense DCB-2, complete genomeisocitrate dehydrogenase, NADP-dependent8e-123440
NC_014376:3593500:3609585360958536107811197Clostridium saccharolyticum WM1 chromosome, complete genomeisocitrate dehydrogenase, NADP-dependent5e-122437
NC_009617:4836000:4836342483634248375501209Clostridium beijerinckii NCIMB 8052 chromosome, complete genomeisocitrate dehydrogenase2e-120432
NC_014387:1362440:1362440136244013636451206Butyrivibrio proteoclasticus B316 chromosome 1, complete genomeisocitrate dehydrogenase Icd4e-120431
NC_011661:203929:2067872067872079921206Dictyoglomus turgidum DSM 6724, complete genomeisocitrate dehydrogenase, NADP-dependent9e-116417
NC_019960:1362370:1379136137913613803381203Prevotella dentalis DSM 3688 chromosome 1, complete sequenceisocitrate dehydrogenase, NADP-dependent3e-114412
NC_006138:857692:8752518752518764591209Desulfotalea psychrophila LSv54, complete genomeisocitrate dehydrogenase2e-110399
NC_009480:99640:103059103059103187129Clavibacter michiganensis subsp. michiganensis NCPPB 382, complete6e-1479
NC_005861:2120633:2137886213788621393371452Candidatus Protochlamydia amoebophila UWE25, complete genomeisocitrate dehydrogenase2e-0757
NC_006833:449132:4659184659184673451428Wolbachia endosymbiont strain TRS of Brugia malayi, completeisocitrate dehydrogenase3e-0653.5