Pre_GI: BLASTN Hits

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Query: NC_005945:3321600 Bacillus anthracis str. Sterne, complete genome

Start: 3321600, End: 3344771, Length: 23172

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_007530:33210333321033334647025438Bacillus anthracis str. 'Ames Ancestor', complete genome016740BLASTN svgBLASTP svg
NC_003997:33209063320906334634325438Bacillus anthracis str. Ames, complete genome016740BLASTN svgBLASTP svg
NC_005945:75451775451777374519229Bacillus anthracis str. Sterne, complete genome7e-0763.9BLASTN svgBLASTP svg
NC_003909:4484278*4484278451179927522Bacillus cereus ATCC 10987, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_004722:46456784645678466921723540Bacillus cereus ATCC 14579, complete genome8e-22113BLASTN svgBLASTP svg
NC_014335:44425004442500446047217973Bacillus cereus biovar anthracis str. CI chromosome, complete4e-0867.9BLASTN svgBLASTP svg
NC_006274:4563455*4563455458739323939Bacillus cereus E33L, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_011772:4638000*4638000466192523926Bacillus cereus G9842, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_006270:2657726*2657726268193124206Bacillus licheniformis ATCC 14580, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_006270:2172693*2172693219944026748Bacillus licheniformis ATCC 14580, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_006322:26585872658587268279124205Bacillus licheniformis ATCC 14580, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_006322:21735002173500220028526786Bacillus licheniformis ATCC 14580, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_014976:75912975912979330034172Bacillus subtilis BSn5 chromosome, complete genome2e-108400BLASTN svgBLASTP svg
NC_010184:4532262*4532262455888726626Bacillus weihenstephanensis KBAB4, complete genome3e-0971.9BLASTN svgBLASTP svg