Pre_GI: BLASTP Hits

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Query: NC_005945:5011857:5023301 Bacillus anthracis str. Sterne, complete genome

Start: 5023301, End: 5023537, Length: 237

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:5009320:501495950149595015195237Bacillus cereus F837/76 chromosome, complete genomehypothetical protein2e-37154
NC_003997:5006193:502196650219665022202237Bacillus anthracis str. Ames, complete genomehypothetical protein2e-37154
NC_014335:4969549:497503749750374975273237Bacillus cereus biovar anthracis str. CI chromosome, completehypothetical protein2e-37154
NC_006274:5085860:509134850913485091584237Bacillus cereus E33L, complete genomehypothetical protein2e-37154
NC_003909:4996783:500026450002645000500237Bacillus cereus ATCC 10987, complete genomehypothetical protein2e-37154
NC_012472:5055184:506082350608235061059237Bacillus cereus 03BB102, complete genomehypothetical protein2e-37154
NC_007530:5006319:502209250220925022328237Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein2e-37154
NC_011658:5049349:505551150555115055747237Bacillus cereus AH187 chromosome, complete genomehypothetical protein2e-37154
NC_011969:4993386:499954949995494999785237Bacillus cereus Q1 chromosome, complete genomehypothetical protein2e-37154
NC_012581:5008749:502452250245225024758237Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein2e-37154
NC_012659:5006219:502199250219925022228237Bacillus anthracis str. A0248, complete genomehypothetical protein2e-37154
NC_010184:5051287:505481450548145055110297Bacillus weihenstephanensis KBAB4, complete genomehypothetical protein6e-37152
NC_004722:5194000:520021052002105200446237Bacillus cereus ATCC 14579, complete genomehypothetical protein2e-35147
NC_011772:5158680:516200951620095162245237Bacillus cereus G9842, complete genomehypothetical protein2e-35147
NC_011725:5201995:520815852081585208394237Bacillus cereus B4264 chromosome, complete genomehypothetical protein2e-35147
NC_017208:5273500:527575252757525275988237Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein2e-35147
NC_009674:3863667:386919738691973869433237Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein5e-34142
NC_021171:4588792:461677946167794617015237Bacillus sp. 1NLA3E, complete genomehypothetical protein2e-1684.3
NC_002952:2256000:225842222584222258655234Staphylococcus aureus subsp. aureus MRSA252, complete genomehypothetical protein1e-1168.6
NC_007622:2117188:211856421185642118797234Staphylococcus aureus RF122, complete genomeprobable membrane protein1e-1168.6
NC_007795:2163706:216664421666442166877234Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein1e-1168.6
NC_010079:2217767:222011622201162220349234Staphylococcus aureus subsp. aureus USA300_TCH1516, completehypothetical protein1e-1168.6
NC_002758:2227874:223081222308122231045234Staphylococcus aureus subsp. aureus Mu50, complete genomehypothetical protein1e-1168.6
NC_009782:2230000:223245022324502232683234Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein1e-1168.6
NC_003923:2178000:218102421810242181257234Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein1e-1168.6
NC_002953:2157781:216012921601292160362234Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein1e-1168.6
NC_007793:2217872:221972222197222219955234Staphylococcus aureus subsp. aureus USA300, complete genomehypothetical protein1e-1168.6
NC_002951:2153571:215592021559202156153234Staphylococcus aureus subsp. aureus COL, complete genomehypothetical protein1e-1168.6
NC_002745:2152000:215438021543802154613234Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein1e-1168.6
NC_017351:2199644:220258122025812202814234Staphylococcus aureus subsp. aureus 11819-97 chromosome, completehypothetical protein1e-1168.6
NC_017342:1147517:116261211626121162845234Staphylococcus aureus subsp. aureus TCH60 chromosome, completehypothetical protein1e-1168.6
NC_017341:2247696:225004522500452250278234Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,hypothetical protein1e-1168.6
NC_017337:2186449:219075621907562190989234Staphylococcus aureus subsp. aureus ED133 chromosome, completemembrane protein1e-1168.6
NC_016912:2035589:203793820379382038171234Staphylococcus aureus subsp. aureus VC40 chromosome, completehypothetical protein1e-1168.6
NC_009641:2221891:222430322243032224536234Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein1e-1168.6
NC_009632:2257764:226070222607022260935234Staphylococcus aureus subsp. aureus JH1 chromosome, completehypothetical protein1e-1168.6
NC_009487:2257889:226082722608272261060234Staphylococcus aureus subsp. aureus JH9 chromosome, completehypothetical protein1e-1168.6
NC_016928:2121919:212376921237692124002234Staphylococcus aureus subsp. aureus M013 chromosome, completehypothetical protein2e-1168.2