Pre_GI: BLASTP Hits

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Query: NC_005945:4473790:4473790 Bacillus anthracis str. Sterne, complete genome

Start: 4473790, End: 4474188, Length: 399

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013282:3962188:398294739829473983354408Cronobacter turicensis, complete genomeLarge-conductance mechanosensitive channel7e-22102
CP002185:3627992:365099336509933651403411Escherichia coli W, complete genomemechanosensitive channel9e-22102
NC_009348:1064664:106628510662851066692408Aeromonas salmonicida subsp. salmonicida A449, complete genomelarge-conductance mechanosensitive channel2e-21100
NC_006511:3364448:338767633876763388089414Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCClarge-conductance mechanosensitive channel7e-2199.4
NC_015914:621411:623555623555623974420Cyclobacterium marinum DSM 745 chromosome, complete genomeLarge-conductance mechanosensitive channel1e-2098.2
NC_013508:3387272:338879633887963389203408Edwardsiella tarda EIB202, complete genomelarge-conductance mechanosensitive channel4e-2096.7
NC_011146:1429836:143905414390541439458405Geobacter bemidjiensis Bem, complete genomelarge conductance mechanosensitive channel protein7e-1992.4
NC_018867:1161648:116164811616481162052405Dehalobacter sp. CF chromosome, complete genomeLarge-conductance mechanosensitive channel5e-1889.7
NC_016776:5174606:521132052113205211742423Bacteroides fragilis 638R, complete genomeputative large-conductance mechanosensitive channel3e-1787.4
NC_008254:102465:118021118021118449429Mesorhizobium sp. BNC1, complete genomelarge conductance mechanosensitive channel protein2e-1684.3
NC_014323:4619344:464673646467364647173438Herbaspirillum seropedicae SmR1 chromosome, complete genomelarge conductance mechanosensitive channel protein2e-1684.3
NC_014355:220002:236105236105236533429Candidatus Nitrospira defluvii, complete genomelarge-conductance mechanosensitive channel2e-1684
NC_003902:3666544:373690137369013737332432Xanthomonas campestris pv. campestris str. ATCC 33913, completelarge-conductance mechanosensitive channel3e-1684
NC_015978:352478:372607372607372981375Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completeLarge-conductance mechanosensitive channel3e-1683.6
NC_013656:2382000:239589923958992396267369Lactococcus lactis subsp. lactis KF147, complete genomelarge-conductance mechanosensitive channel4e-1683.6
NC_010161:596034:601845601845602255411Bartonella tribocorum CIP 105476, complete genomehypothetical protein6e-1682.8
NC_015684:2369651:236965123696512370067417Oligotropha carboxidovorans OM5 chromosome, complete genomelarge-conductance mechanosensitive channel MscL8e-1682.4
NC_010002:6104500:610880961088096109237429Delftia acidovorans SPH-1, complete genomelarge conductance mechanosensitive channel protein4e-1580.1
NC_015563:1240978:125643412564341256862429Delftia sp. Cs1-4 chromosome, complete genomelarge conductance mechanosensitive channel protein4e-1580.1
NC_002678:3701500:373064737306473731081435Mesorhizobium loti MAFF303099, complete genomemechanosensitive channel5e-1579.7
NC_010682:3313944:335562233556223356050429Ralstonia pickettii 12J chromosome 1, complete sequencelarge conductance mechanosensitive channel protein1e-1478.6
NC_011992:773905:780102780102780530429Acidovorax ebreus TPSY, complete genomelarge conductance mechanosensitive channel protein1e-1478.6
NC_014307:533975:537543537543537968426Ralstonia solanacearum CFBP2957 chromosome, complete genomelarge-conductance mechanosensitive channel2e-1477.8
NC_014834:3472000:348881234888123489222411Rhodopseudomonas palustris DX-1 chromosome, complete genomelarge conductance mechanosensitive channel protein2e-1477.8
NC_010814:155834:163539163539163982444Geobacter lovleyi SZ, complete genomelarge conductance mechanosensitive channel protein3e-1477.4
NC_014718:232832:257083257083257559477Burkholderia rhizoxinica HKI 454 chromosome, complete genomeLarge-conductance mechanosensitive channel3e-1477.4
NC_002678:3701500:374379037437903744212423Mesorhizobium loti MAFF303099, complete genomelarge conductance mechanosensitive channel4e-1476.6
NC_011027:1024995:104691910469191047374456Chlorobaculum parvum NCIB 8327, complete genomelarge conductance mechanosensitive channel protein6e-1476.3
NC_012856:3000839:301706730170673017495429Ralstonia pickettii 12D chromosome 1, complete genomelarge conductance mechanosensitive channel protein6e-1476.3
NC_014935:1668461:169005016900501690484435Nitratifractor saLSUginis DSM 16511 chromosome, complete genomelarge conductance mechanosensitive channel protein7e-1475.9
NC_008529:264000:266698266698267174477Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365, completeLarge-conductance mechanosensitive channel1e-1375.5
NC_010162:9727465:973099097309909731439450Sorangium cellulosum 'So ce 56', complete genomelarge conductance mechanosensitive channel9e-1475.5
NC_002678:4618555:462994646299464630367422Mesorhizobium loti MAFF303099, complete genome1e-1375.1
NC_013595:9547254:955105695510569551460405Streptosporangium roseum DSM 43021, complete genomelarge conductance mechanosensitive channel protein3e-1373.9
NC_014150:648868:651967651967652431465Brachyspira murdochii DSM 12563 chromosome, complete genomelarge conductance mechanosensitive channel protein4e-1373.6
NC_014209:1392115:140480614048061405174369Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,large conductance mechanosensitive channel protein5e-1373.2
NC_010320:1860801:186132418613241861704381Thermoanaerobacter sp. X514 chromosome, complete genomelarge conductance mechanosensitive channel protein6e-1372.8
NC_014538:1075720:109264010926401093020381Thermoanaerobacter sp. X513 chromosome, complete genomelarge conductance mechanosensitive channel protein6e-1372.8
NC_013174:2163947:216573421657342166132399Jonesia denitrificans DSM 20603, complete genomelarge conductance mechanosensitive channel protein1e-1272
NC_015846:493388:518074518074518454381Capnocytophaga canimorsus Cc5 chromosome, complete genomeLarge-conductance mechanosensitive channel1e-1272
NC_007777:75885:886998869989094396Frankia sp. CcI3, complete genomelarge conductance mechanosensitive channel protein9e-1372
NC_013171:1364464:138535613853561385766411Anaerococcus prevotii DSM 20548, complete genomelarge conductance mechanosensitive channel protein4e-1270.1
NC_010321:947233:962410962410962778369Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completelarge conductance mechanosensitive channel protein1e-1168.6
NC_014964:923681:954603954603954971369Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completelarge conductance mechanosensitive channel protein1e-1168.6
NC_017167:129988:134618134618135076459Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1large conductance mechanosensitive channel protein3e-1167.4
NC_016002:1326500:133847113384711338902432Pseudogulbenkiania sp. NH8B, complete genomelarge conductance mechanosensitive channel protein2e-1064.7
NC_017080:50000:579395793958397459Phycisphaera mikurensis NBRC 102666, complete genomelarge-conductance mechanosensitive channel2e-1064.7
NC_013222:2595315:261570126157012616135435Robiginitalea biformata HTCC2501, complete genomelarge conductance mechanosensitive channel protein3e-1063.9
NC_013510:991827:100630710063071006711405Thermomonospora curvata DSM 43183, complete genomelarge conductance mechanosensitive channel protein4e-1063.2
NC_015759:1117122:113952211395221139905384Weissella koreensis KACC 15510 chromosome, complete genomelarge conductance mechanosensitive channel protein5e-1063.2
NC_015389:905165:922842922842923309468Coriobacterium glomerans PW2 chromosome, complete genomelarge conductance mechanosensitive channel protein7e-1062.8
NC_016109:3525588:353665335366533537087435Kitasatospora setae KM-6054, complete genomeputative large-conductance mechanosensitive channel7e-0959.3
NC_012467:916000:932535932535932912378Streptococcus pneumoniae P1031, complete genomelarge conductance mechanosensitive channel protein8e-0958.9
NC_011886:2950411:295657929565792956968390Arthrobacter chlorophenolicus A6, complete genomelarge conductance mechanosensitive channel protein1e-0858.2
NC_008541:3282415:328640832864083286800393Arthrobacter sp. FB24 chromosome 1, complete sequencelarge conductance mechanosensitive channel protein3e-0857.4
NC_008618:10915:124521245212895444Bifidobacterium adolescentis ATCC 15703, complete genomelarge-conductance mechanosensitive channel1e-0755.5
NC_015145:2942500:294651629465162946926411Arthrobacter phenanthrenivorans Sphe3 chromosome, complete genomelarge conductance mechanosensitive channel protein1e-0755.1
NC_018750:3315309:332050733205073321115609Streptomyces venezuelae ATCC 10712, complete genomeLarge-conductance mechanosensitive channel2e-0754.7
NC_008278:81866:980189801898413396Frankia alni ACN14a, complete genomemechanosensitive channel3e-0753.9
NC_010407:32960:438054380544287483Clavibacter michiganensis subsp. sepedonicus chromosome, completeputative mechanosensitive channel5e-0753.1
NC_017186:9120711:915435891543589154774417Amycolatopsis mediterranei S699 chromosome, complete genomelarge conductance mechanosensitive channel, MscL family protein5e-0650.1
NC_010572:3363830:341006134100613410528468Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative large-conductance mechanosensitive channel protein6e-0649.7