Pre_GI: BLASTP Hits

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Query: NC_005945:4116978:4120746 Bacillus anthracis str. Sterne, complete genome

Start: 4120746, End: 4121945, Length: 1200

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:4116971:4120272412027241214711200Bacillus anthracis str. A0248, complete genomesporulation protein0684
NC_016771:4059445:4066799406679940679981200Bacillus cereus NC7401, complete genomesporulation protein0675
NC_011969:4001489:4008103400810340093021200Bacillus cereus Q1 chromosome, complete genomesporulation protein0675
NC_011658:4107501:4113015411301541142141200Bacillus cereus AH187 chromosome, complete genomesporulation protein0675
NC_011772:4255161:4256124425612442573231200Bacillus cereus G9842, complete genomesporulation protein0659
NC_017208:4294341:4295304429530442965031200Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeputative stage IV sporulation protein0659
NC_014171:4178746:4179709417970941809081200Bacillus thuringiensis BMB171 chromosome, complete genomestage IV sporulation protein0659
NC_011725:4288309:4289272428927242904711200Bacillus cereus B4264 chromosome, complete genomesporulation protein0659
NC_004722:4244730:4245693424569342468921200Bacillus cereus ATCC 14579, complete genomeputative stage IV sporulation protein0659
NC_010184:4155345:4158650415865041598491200Bacillus weihenstephanensis KBAB4, complete genomeputative stage IV sporulation YqfD0654
NC_003909:4064904:4068672406867240698711200Bacillus cereus ATCC 10987, complete genomesporulation protein0676
NC_006274:4159096:4162397416239741635961200Bacillus cereus E33L, complete genomeprobable stage IV sporulation protein0677
NC_012581:4118366:4121667412166741228661200Bacillus anthracis str. CDC 684 chromosome, complete genomesporulation protein0684
NC_003997:4116944:4120245412024541214441200Bacillus anthracis str. Ames, complete genomesporulation protein0684
NC_007530:4117071:4120372412037241215711200Bacillus anthracis str. 'Ames Ancestor', complete genomesporulation protein0684
NC_016779:4039103:4042404404240440436031200Bacillus cereus F837/76 chromosome, complete genomeStage IV sporulation protein0681
NC_011773:4108855:4112156411215641133551200Bacillus cereus AH820 chromosome, complete genomesporulation protein0681
NC_012472:4119192:4124706412470641259051200Bacillus cereus 03BB102, complete genomesporulation protein0681
NC_008600:4101748:4107262410726241084611200Bacillus thuringiensis str. Al Hakam, complete genomestage IV sporulation protein0681
NC_005957:4104880:4108181410818141093801200Bacillus thuringiensis serovar konkukian str. 97-27, completeprobable stage IV sporulation protein0681
NC_014335:4027105:4030406403040640316051200Bacillus cereus biovar anthracis str. CI chromosome, completestage IV sporulation protein0677
NC_009674:3073564:3079089307908930802881200Bacillus cytotoxicus NVH 391-98 chromosome, complete genomeputative stage IV sporulation YqfD3e-168591
NC_002570:1426000:1445063144506314462561194Bacillus halodurans C-125, complete genomestage IV sporulation protein9e-73274
NC_009633:3055413:3066367306636730675991233Alkaliphilus metalliredigens QYMF chromosome, complete genomeputative stage IV sporulation YqfD9e-26118
NC_011898:649000:6647786647786659741197Clostridium cellulolyticum H10, complete genomesporulation protein YqfD2e-1996.7
NC_008593:1704207:1706288170628817074961209Clostridium novyi NT, complete genomestage IV sporulation protein, putative8e-1995.1
NC_021182:2192718:2213216221321622143581143Clostridium pasteurianum BC1, complete genomesporulation protein YqfD2e-1687
NC_018515:4148037:4151064415106441522391176Desulfosporosinus meridiei DSM 13257 chromosome, complete genomesporulation protein YqfD4e-1376.3
NC_012563:3374904:3378250337825033794101161Clostridium botulinum A2 str. Kyoto, complete genomesporulation protein YqfD7e-1168.9
NC_017297:3178378:3182206318220631833661161Clostridium botulinum F str. 230613 chromosome, complete genomeputative stage IV sporulation protein1e-1067.8
NC_009699:3178222:3182050318205031832101161Clostridium botulinum F str. Langeland chromosome, complete genomestage IV sporulation protein1e-1067.8
NC_010520:3204480:3207826320782632089861161Clostridium botulinum A3 str. Loch Maree, complete genomeputative stage IV sporulation protein1e-1067.8
NC_012658:3213498:3216844321684432180041161Clostridium botulinum Ba4 str. 657 chromosome, complete genomesporulation protein YqfD2e-1067
NC_009495:3138355:3141699314169931428591161Clostridium botulinum A str. ATCC 3502 chromosome, complete genomestage IV sporulation protein2e-1067.4
NC_009697:3071198:3074542307454230757021161Clostridium botulinum A str. ATCC 19397 chromosome, completestage IV sporulation protein2e-1067.4
NC_009698:3006500:3011464301146430126241161Clostridium botulinum A str. Hall chromosome, complete genomestage IV sporulation protein2e-1067.4
NC_010516:3196158:3199504319950432006641161Clostridium botulinum B1 str. Okra, complete genomeputative stage IV sporulation protein2e-1067.8
NC_020291:1014333:1029549102954910306641116Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomesporulation protein YqfD2e-0757.4
NC_008261:2524913:2527004252700425281401137Clostridium perfringens ATCC 13124, complete genomeputative stage IV sporulation protein2e-0757.4