Pre_GI: BLASTP Hits

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Query: NC_005945:3992600:3992600 Bacillus anthracis str. Sterne, complete genome

Start: 3992600, End: 3993034, Length: 435

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007530:3992228:399222839922283992662435Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein9e-82301
NC_011773:3982008:398444839844483984882435Bacillus cereus AH820 chromosome, complete genomehypothetical protein9e-82301
NC_014335:3902155:390215539021553902589435Bacillus cereus biovar anthracis str. CI chromosome, completeMerR family transcriptional regulator6e-81298
NC_016779:3913627:391362739136273914061435Bacillus cereus F837/76 chromosome, complete genomehypothetical protein6e-81298
NC_011772:4125996:412623741262374126671435Bacillus cereus G9842, complete genomehypothetical protein8e-81298
NC_011969:3879412:388189838818983882311414Bacillus cereus Q1 chromosome, complete genomehypothetical protein3e-77286
NC_009674:1707944:172046917204691720903435Bacillus cytotoxicus NVH 391-98 chromosome, complete genomehypothetical protein3e-37153
NC_005957:3975192:397870239787023979136435Bacillus thuringiensis serovar konkukian str. 97-27, completehypothetical protein3e-81299
NC_008600:3976045:397848539784853978919435Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein6e-81298
NC_010184:4021688:402341440234144023848435Bacillus weihenstephanensis KBAB4, complete genomeprotein of unknown function DUF10948e-81298
NC_010830:1291415:130929413092941309794501Candidatus Amoebophilus asiaticus 5a2, complete genomehypothetical protein9e-2199
NC_014915:2427000:245121724512172451654438Geobacillus sp. Y412MC52 chromosome, complete genomeprotein of unknown function DUF10941e-57221
NC_013411:284461:287834287834288271438Geobacillus sp. Y412MC61, complete genomeprotein of unknown function DUF10941e-57221
NC_007677:1847913:186018118601811860852672Salinibacter ruber DSM 13855, complete genomeProtein of unknown function (DUF1094) family1e-26118
NC_014032:1911500:192373419237341924246513Salinibacter ruber M8 chromosome, complete genomehypothetical protein3e-27120
NC_007622:1397407:139946613994661399903438Staphylococcus aureus RF122, complete genomehypothetical protein3e-27120
NC_017351:1464209:146558914655891466026438Staphylococcus aureus subsp. aureus 11819-97 chromosome, completehypothetical protein3e-27120
NC_002951:1474465:147584514758451476282438Staphylococcus aureus subsp. aureus COL, complete genomehypothetical protein3e-27120
NC_017343:1391124:139250413925041392941438Staphylococcus aureus subsp. aureus ECT-R 2, complete genomehypothetical protein3e-27120
NC_017337:1478448:147982814798281480265438Staphylococcus aureus subsp. aureus ED133 chromosome, completehypothetical protein9e-27118
NC_013450:1446952:144833214483321448769438Staphylococcus aureus subsp. aureus ED98, complete genomehypothetical protein3e-27120
NC_009632:1557122:155850215585021558939438Staphylococcus aureus subsp. aureus JH1 chromosome, completehypothetical protein3e-27120
NC_009487:1557248:155862815586281559065438Staphylococcus aureus subsp. aureus JH9 chromosome, completehypothetical protein3e-27120
NC_017338:1419500:142087614208761421313438Staphylococcus aureus subsp. aureus JKD6159 chromosome, completehypothetical protein9e-27118
NC_016928:1440319:144169914416991442136438Staphylococcus aureus subsp. aureus M013 chromosome, completehypothetical protein2e-27120
NC_002952:1497785:149916514991651499602438Staphylococcus aureus subsp. aureus MRSA252, complete genomehypothetical protein3e-26117
NC_016941:1411500:141442014144201414857438Staphylococcus aureus subsp. aureus MSHR1132, complete genomehypothetical protein6e-27119
NC_002953:1464693:146607314660731466510438Staphylococcus aureus subsp. aureus MSSA476, complete genomehypothetical protein3e-27120
NC_009782:1510396:151177615117761512213438Staphylococcus aureus subsp. aureus Mu3, complete genomehypothetical protein3e-27120
NC_002758:1508996:151037615103761510813438Staphylococcus aureus subsp. aureus Mu50, complete genomehypothetical protein3e-27120
NC_003923:1436139:143751914375191437956438Staphylococcus aureus subsp. aureus MW2, complete genomehypothetical protein3e-27120
NC_002745:1432585:143396514339651434402438Staphylococcus aureus subsp. aureus N315, complete genomehypothetical protein3e-27120
NC_007795:1370500:137206913720691372506438Staphylococcus aureus subsp. aureus NCTC 8325, complete genomehypothetical protein3e-27120
NC_017341:1482882:148426214842621484699438Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,hypothetical protein3e-27120
NC_009641:1470500:147202514720251472462438Staphylococcus aureus subsp. aureus str. Newman chromosome,hypothetical protein3e-27120
NC_017347:1483163:148454314845431484980438Staphylococcus aureus subsp. aureus T0131 chromosome, completehypothetical protein3e-27120
NC_017342:1848031:188585818858581886310453Staphylococcus aureus subsp. aureus TCH60 chromosome, completeYqiW like protein2e-26117
NC_007793:1451409:145278914527891453226438Staphylococcus aureus subsp. aureus USA300, complete genomehypothetical protein3e-27120
NC_010079:1465356:146673614667361467173438Staphylococcus aureus subsp. aureus USA300_TCH1516, completehypothetical protein3e-27120
NC_016912:1374351:137573113757311376168438Staphylococcus aureus subsp. aureus VC40 chromosome, completehypothetical protein3e-27120
NC_004461:1132670:113267011326701133107438Staphylococcus epidermidis ATCC 12228, complete genomehypothetical protein2e-25114