Pre_GI: BLASTP Hits

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Query: NC_005945:1334000:1337120 Bacillus anthracis str. Sterne, complete genome

Start: 1337120, End: 1337587, Length: 468

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:1334000:133707413370741337541468Bacillus anthracis str. A0248, complete genomehypothetical protein1e-72271
NC_012581:2885519:290155429015542902021468Bacillus anthracis str. CDC 684 chromosome, complete genomehypothetical protein1e-72271
NC_011773:1402155:140275314027531403220468Bacillus cereus AH820 chromosome, complete genomehypothetical protein7e-72268
NC_006274:1367377:137177413717741372241468Bacillus cereus E33L, complete genomehypothetical protein7e-72268
NC_016779:1321723:132369813236981324165468Bacillus cereus F837/76 chromosome, complete genomehypothetical protein3e-71266
NC_012472:1339500:134011313401131340580468Bacillus cereus 03BB102, complete genomehypothetical protein3e-71266
NC_008600:1396471:139706913970691397536468Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein3e-71266
NC_014335:1329414:133382513338251334292468Bacillus cereus biovar anthracis str. CI chromosome, completeputative YtfJ-like protein6e-71265
NC_011969:1437514:144153314415331442087555Bacillus cereus Q1 chromosome, complete genomehypothetical protein2e-69260
NC_011772:1329730:133167213316721332139468Bacillus cereus G9842, complete genomehypothetical protein1e-67254
NC_011725:1383798:138825513882551388722468Bacillus cereus B4264 chromosome, complete genomehypothetical protein4e-67253
NC_007530:1332768:133723413372341337641408Bacillus anthracis str. 'Ames Ancestor', complete genomehypothetical protein1e-60231
NC_003997:1334000:133711113371111337518408Bacillus anthracis str. Ames, complete genomehypothetical protein1e-60231
NC_011658:1437813:144198514419851442386402Bacillus cereus AH187 chromosome, complete genomehypothetical protein2e-57221
NC_016771:1397292:140146414014641401865402Bacillus cereus NC7401, complete genomehypothetical protein2e-57221
NC_010184:1373375:137543513754351375842408Bacillus weihenstephanensis KBAB4, complete genomeSporulation protein YtfJ1e-57221
NC_014171:1356000:136012113601211360528408Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein6e-56216
NC_017208:1380870:138211613821161382523408Bacillus thuringiensis serovar chinensis CT-43 chromosome, completehypothetical protein4e-55213
NC_004722:1352000:135651213565121356823312Bacillus cereus ATCC 14579, complete genomehypothetical protein1e-38158
NC_011772:4565418:456723945672394567634396Bacillus cereus G9842, complete genomehypothetical protein1e-22105
NC_011725:4600000:460192346019234602318396Bacillus cereus B4264 chromosome, complete genomehypothetical protein2e-22104
NC_016012:561687:580365580365580751387Candidatus Arthromitus sp. SFB-rat-Yit, complete genomesporulation protein YtfJ1e-1582
NC_015687:2145452:216508621650862165562477Clostridium acetobutylicum DSM 1731 chromosome, complete genomehypothetical protein5e-1580.1
NC_010321:1177238:118253111825311182977447Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completehypothetical protein1e-1479
NC_014964:1169925:117472211747221175168447Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completesporulation protein YtfJ1e-1479
NC_015913:624859:640860640860641246387Candidatus Arthromitus sp. SFB-mouse-Japan, complete genomesporulation protein YtfJ2e-1478.2
NC_020134:586840:590052590052590501450Clostridium stercorarium subsp. stercorarium DSM 8532, completesporulation protein YtfJ2e-1478.2
NC_010320:1585974:158900015890001589446447Thermoanaerobacter sp. X514 chromosome, complete genomehypothetical protein3e-1477.4
NC_014538:1311500:132493613249361325382447Thermoanaerobacter sp. X513 chromosome, complete genomesporulation protein YtfJ3e-1477.4
NC_010674:2435241:245594224559422456424483Clostridium botulinum B str. Eklund 17B, complete genomesporulation protein YtfJ1e-1168.9