Pre_GI: BLASTP Hits

Some Help

Query: NC_005945:1103729:1121148 Bacillus anthracis str. Sterne, complete genome

Start: 1121148, End: 1121354, Length: 207

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:1103737:112115611211561121362207Bacillus anthracis str. A0248, complete genomespore germination protein GerPB1e-2098.6
NC_011725:1150779:116825411682541168460207Bacillus cereus B4264 chromosome, complete genomespore germination protein GerPB2e-2097.4
NC_011772:1094534:111215611121561112362207Bacillus cereus G9842, complete genomespore germination protein GerPB8e-2095.5
NC_011969:1181302:119743111974311197637207Bacillus cereus Q1 chromosome, complete genomespore germination protein gerpb2e-2097.4
NC_010184:1114000:112829911282991128505207Bacillus weihenstephanensis KBAB4, complete genomespore germination protein GerPB6e-2096.3
NC_003909:1244000:126050412605041260710207Bacillus cereus ATCC 10987, complete genomespore germination protein GerPB2e-2097.4
NC_014335:1094000:111249811124981112704207Bacillus cereus biovar anthracis str. CI chromosome, completespore germination protein PB1e-2098.6
NC_004722:1108649:112619311261931126399207Bacillus cereus ATCC 14579, complete genomeSpore germination protein PB2e-2097.4
NC_017208:1147230:116474611647461164952207Bacillus thuringiensis serovar chinensis CT-43 chromosome, completespore germination protein PB2e-2097.4