Pre_GI: BLASTP Hits

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Query: NC_005945:1103729:1112031 Bacillus anthracis str. Sterne, complete genome

Start: 1112031, End: 1115546, Length: 3516

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:1103737:1112039111203911155543516Bacillus anthracis str. A0248, complete genomeATP-dependent nuclease, subunit B02429
NC_007644:469181:4885524885524920073456Moorella thermoacetica ATCC 39073, complete genomeATP-dependent deoxyribonuclease subunit B0804
NC_014328:773095:7730957730957765473453Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative ATP-dependent nuclease subunit B0778
NC_016627:3972751:3978953397895339824263474Clostridium clariflavum DSM 19732 chromosome, complete genomeDNA helicase/exodeoxyribonuclease V subunit B0770
NC_004557:691944:7034027034027068753474Clostridium tetani E88, complete genomeATP-dependent nuclease subunit B0760
NC_021182:2360500:2363815236381523672793465Clostridium pasteurianum BC1, complete genomehelicase-exonuclease AddAB, AddB subunit0759
NC_007907:1940000:1962315196231519659773663Desulfitobacterium hafniense Y51, complete genomehypothetical protein0753
NC_011830:3025437:3047848304784830515043657Desulfitobacterium hafniense DCB-2, complete genomeATP-dependent nuclease subunit B0751
NC_009089:1202261:1224399122439912278663468Clostridium difficile 630, complete genomeATP-dependent nuclease subunit B0731
NC_013316:1081044:1103112110311211065793468Clostridium difficile R20291, complete genomeATP-dependent nuclease subunit B0729
NC_015425:369225:3692253692253726653441Clostridium botulinum BKT015925 chromosome, complete genomeATP-dependent deoxyribonuclease subunit B0724
NC_020291:1:1865218652221283477Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeATP-dependent helicase/deoxyribonuclease subunit B0668
NC_021184:3793285:3802339380233938059173579Desulfotomaculum gibsoniae DSM 7213, complete genomehelicase-exonuclease AddAB, AddB subunit0874
NC_016641:5528826:5543785554378555473513567Paenibacillus terrae HPL-003 chromosome, complete genomeATP-dependent nuclease subunit B0951
NC_014483:3498395:3510676351067635142453570Paenibacillus polymyxa E681 chromosome, complete genomeATP-dependent nuclease subunit B0961
NC_014335:1094000:1101790110179011053053516Bacillus cereus biovar anthracis str. CI chromosome, completeATP-dependent nuclease subunit B02414
NC_003909:1244000:1251340125134012548553516Bacillus cereus ATCC 10987, complete genomeATP-dependent nuclease, subunit B02412
NC_011969:1181302:1188318118831811918333516Bacillus cereus Q1 chromosome, complete genomeATP-dependent nuclease, subunit b02411
NC_011725:1150779:1159036115903611625513516Bacillus cereus B4264 chromosome, complete genomeATP-dependent nuclease subunit B02367
NC_014171:1118000:1124833112483311283483516Bacillus thuringiensis BMB171 chromosome, complete genomeATP-dependent nuclease subunit B02365
NC_017208:1147230:1155528115552811590433516Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeATP-dependent nuclease subunit B02362
NC_011772:1094534:1102938110293811064533516Bacillus cereus G9842, complete genomeATP-dependent nuclease, subunit B02362
NC_004722:1108649:1116979111697911204943516Bacillus cereus ATCC 14579, complete genomeATP-dependent nuclease subunit B02356
NC_010184:1114000:1118237111823711217523516Bacillus weihenstephanensis KBAB4, complete genomeATP-dependent nuclease subunit AddB02324
NC_016047:1234743:1250727125072712542273501Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completeATP-dependent nuclease subunit B01177
NC_014622:3819495:3831345383134538349113567Paenibacillus polymyxa SC2 chromosome, complete genomeATP-dependent nuclease subunit b0962
NC_014614:260782:2642142642142675703357Clostridium sticklandii, complete genomeATP-dependent deoxyribonuclease (subunit B)2e-154547
NC_013520:1905554:1916484191648419200413558Veillonella parvula DSM 2008, complete genomeATP-dependent nuclease subunit B-like protein9e-136485
NC_015428:2291430:2311828231182823153883561Lactobacillus buchneri NRRL B-30929 chromosome, complete genomeATP-dependent helicase/deoxyribonuclease subunit B1e-135484
NC_015978:1266196:1266196126619612697533558Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completeATP-dependent helicase/deoxyribonuclease subunit B3e-134480
NC_009785:1443500:1460513146051314637943282Streptococcus gordonii str. Challis substr. CH1, complete genomeputative exonuclease RexB8e-41169
NC_015067:1528984:1558582155858215618783297Bifidobacterium longum subsp. longum JCM 1217, complete genomeATP-dependent nuclease subunit B6e-1584.3