Pre_GI: BLASTP Hits

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Query: NC_005945:1103729:1110701 Bacillus anthracis str. Sterne, complete genome

Start: 1110701, End: 1111294, Length: 594

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012659:1103737:111070911107091111302594Bacillus anthracis str. A0248, complete genomehypothetical protein3e-108390
NC_011969:1181302:118698811869881187581594Bacillus cereus Q1 chromosome, complete genomehypothetical protein3e-108390
NC_003909:1244000:125000912500091250602594Bacillus cereus ATCC 10987, complete genomehypothetical protein3e-108390
NC_014335:1094000:110046011004601101053594Bacillus cereus biovar anthracis str. CI chromosome, completemembrane protein3e-108390
NC_004722:1108649:111564911156491116242594Bacillus cereus ATCC 14579, complete genomeAlkaline phosphatase like protein6e-108389
NC_011772:1094534:110160911016091102202594Bacillus cereus G9842, complete genomehypothetical protein6e-108389
NC_011725:1150779:115770711577071158300594Bacillus cereus B4264 chromosome, complete genomehypothetical protein6e-108389
NC_014171:1118000:112350311235031124096594Bacillus thuringiensis BMB171 chromosome, complete genomealkaline phosphatase-like protein6e-108389
NC_017208:1147230:115419811541981154791594Bacillus thuringiensis serovar chinensis CT-43 chromosome, completealkaline phosphatase like protein9e-108389
NC_010184:1114000:111690611169061117499594Bacillus weihenstephanensis KBAB4, complete genomeSNARE associated Golgi protein2e-102371
NC_016047:1234743:123474312347431235366624Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completehypothetical protein5e-57220
NC_006322:1119471:112112311211231121734612Bacillus licheniformis ATCC 14580, complete genomeYhjE2e-48192
NC_006270:1119000:112027211202721120880609Bacillus licheniformis ATCC 14580, complete genomehypothetical protein2e-48192
NC_014220:1401065:141659614165961417165570Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomeSNARE associated Golgi protein-related protein2e-1685.5
NC_014152:397177:412611412611413156546Thermincola sp. JR, complete genomeSNARE associated Golgi protein-related protein9e-1270.1
NC_010520:2807429:282092428209242821661738Clostridium botulinum A3 str. Loch Maree, complete genomeDedA family protein7e-1167
NC_010516:2777205:279038627903862791123738Clostridium botulinum B1 str. Okra, complete genomeDedA family protein2e-1065.5
NC_017297:2796000:280631228063122807049738Clostridium botulinum F str. 230613 chromosome, complete genomeDedA family protein3e-1065.1
NC_010556:2773396:277921927792192779872654Exiguobacterium sibiricum 255-15, complete genomeSNARE associated Golgi protein5e-1064.3
NC_014221:1167261:116904011690401169852813Truepera radiovictrix DSM 17093 chromosome, complete genomeSNARE associated Golgi protein-like protein2e-0962.8
NC_015602:1339067:135502213550221355630609Lactobacillus kefiranofaciens ZW3 chromosome, complete genomeintegral membrane protein2e-0962.4
NC_017297:2796000:280701528070152807734720Clostridium botulinum F str. 230613 chromosome, complete genomeDedA family protein2e-0962
NC_019970:2190695:220060122006012201278678Thermoanaerobacterium thermosaccharolyticum M0795, complete genomehypothetical protein3e-0961.6
NC_021175:1291707:130703013070301307656627Streptococcus oligofermentans AS 1.3089, complete genomehypothetical protein3e-0961.6
NC_017068:1852708:185777818577781858533756Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative inner membrane protein3e-0961.6
NC_010516:2777205:279108927910892791808720Clostridium botulinum B1 str. Okra, complete genomeDedA family protein4e-0961.2
NC_010520:2807429:282162728216272822346720Clostridium botulinum A3 str. Loch Maree, complete genomeDedA family protein8e-0960.5
NC_014410:2149886:215677721567772157466690Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,SNARE associated Golgi protein9e-0960.1
NC_018528:1681060:169850216985021699101600Lactobacillus helveticus R0052 chromosome, complete genomeintegral membrane protein1e-0859.7
NC_018665:2563375:256901525690152569668654Exiguobacterium antarcticum B7 chromosome, complete genomeSNARE associated Golgi family protein1e-0859.7
NC_013946:2050871:207503020750302075737708Meiothermus ruber DSM 1279 chromosome, complete genomeSNARE associated Golgi protein-like protein1e-0860.1
NC_010674:1170264:117131011713101171876567Clostridium botulinum B str. Eklund 17B, complete genomesnare associated golgi protein2e-0755.8
NC_002937:2068117:213029321302932130973681Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completehypothetical protein2e-0755.8
NC_008751:1431905:143575714357571436437681Desulfovibrio vulgaris subsp. vulgaris DP4, complete genomehypothetical protein2e-0755.5
NC_009495:3502000:351094635109463511680735Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehypothetical protein4e-0754.3
NC_009697:3463736:348693434869343487668735Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein4e-0754.3
NC_012563:3729817:375302037530203753754735Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein4e-0754.7
NC_009699:3581376:360458036045803605314735Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein5e-0754.3
NC_015555:693461:707062707062707739678Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeSNARE associated Golgi protein-like protein5e-0754.3
NC_010723:1133163:113520011352001135760561Clostridium botulinum E3 str. Alaska E43, complete genomemembrane protein, DedA family3e-0651.6
NC_014976:627935:627935627935628561627Bacillus subtilis BSn5 chromosome, complete genomehypothetical protein4e-0651.2
NC_006351:1886475:1886475188647518886612187Burkholderia pseudomallei K96243 chromosome 2, complete sequencetransmembrane phospholipase protein5e-0650.8
NC_009078:1841023:1841023184102318432092187Burkholderia pseudomallei 1106a chromosome II, complete sequencephospholipase D domain protein5e-0650.8
NC_019940:1670262:1670262167026216725172256Thioflavicoccus mobilis 8321 chromosome, complete genomephosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase5e-0650.8
NC_014479:2505823:250582325058232506449627Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehypothetical protein6e-0650.4
UCMB5137:2054735:205947220594722060098627Bacillus atrophaeus UCMB-5137hypothetical protein7e-0650.4
NC_010080:1685280:170159317015931702201609Lactobacillus helveticus DPC 4571, complete genomehypothetical protein8e-0650.4