Pre_GI: BLASTP Hits

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Query: NC_005945:1008000:1013778 Bacillus anthracis str. Sterne, complete genome

Start: 1013778, End: 1014338, Length: 561

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016779:991298:994947994947995507561Bacillus cereus F837/76 chromosome, complete genomeGlycerol uptake operon antiterminator regulatory protein2e-105381
NC_008600:1042477:104838910483891048949561Bacillus thuringiensis str. Al Hakam, complete genomeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_005957:1037205:104247910424791043039561Bacillus thuringiensis serovar konkukian str. 97-27, completeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_003997:1007139:101388510138851014445561Bacillus anthracis str. Ames, complete genomeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_006274:1040836:104658710465871047147561Bacillus cereus E33L, complete genomeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_007530:1007140:101388510138851014445561Bacillus anthracis str. 'Ames Ancestor', complete genomeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_011773:1050000:105608810560881056648561Bacillus cereus AH820 chromosome, complete genomeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_011969:1084000:108871410887141089274561Bacillus cereus Q1 chromosome, complete genomeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_012659:1008028:101378510137851014345561Bacillus anthracis str. A0248, complete genomeglycerol uptake operon antiterminator regulatory protein2e-105381
NC_011772:1011220:101596210159621016522561Bacillus cereus G9842, complete genomeglycerol uptake operon antiterminator regulatory protein3e-104377
NC_017208:1050414:105700810570081057568561Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeglycerol uptake operon antiterminator3e-104377
NC_017200:1157835:116691811669181167478561Bacillus thuringiensis serovar finitimus YBT-020 chromosome,glycerol uptake operon antiterminator regulatory protein2e-104377
NC_004722:1008500:101422710142271014787561Bacillus cereus ATCC 14579, complete genomeGlycerol uptake operon antiterminator regulatory protein2e-104377
NC_011725:1032500:103828110382811038841561Bacillus cereus B4264 chromosome, complete genomeglycerol uptake operon antiterminator regulatory protein2e-104377
NC_010184:1017000:102245410224541023014561Bacillus weihenstephanensis KBAB4, complete genomeglycerol-3-phosphate responsive antiterminator, GlpP4e-100363
NC_014171:1018338:102424810242481024538291Bacillus thuringiensis BMB171 chromosome, complete genomeglycerol uptake operon antiterminator2e-49195
NC_004193:2522000:253484925348492535391543Oceanobacillus iheyensis HTE831, complete genometranscriptional antiterminator of glycerol uptake operon1e-42172
NC_010321:562494:567052567052567621570Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completeglycerol-3-phosphate responsive antiterminator GlpP1e-31136
NC_014964:557910:562468562468563037570Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completeglycerol-3-phosphate responsive antiterminator1e-31136
NC_019978:2036779:204922120492212049790570Halobacteroides halobius DSM 5150, complete genomeglycerol-3-phosphate responsive antiterminator (mRNA-binding)1e-30132
NC_009633:587562:587562587562588128567Alkaliphilus metalliredigens QYMF chromosome, complete genomeglycerol-3-phosphate responsive antiterminator6e-29126
NC_015425:2528549:254676525467652547331567Clostridium botulinum BKT015925 chromosome, complete genomeglycerol uptake operon antiterminator regulatory protein1e-28125
NC_020134:845164:850368850368850937570Clostridium stercorarium subsp. stercorarium DSM 8532, completeglycerol-3-phosphate responsive antiterminator, GlpP3e-28124
NC_008593:2281896:229649022964902297056567Clostridium novyi NT, complete genomeglycerol uptake operon antiterminator regulatory protein8e-27119
NC_010723:1014334:101949410194941020054561Clostridium botulinum E3 str. Alaska E43, complete genomeglycerol-3-phosphate responsive antiterminator2e-25115
NC_011415:308825:308825308825309376552Escherichia coli SE11 chromosome, complete genomeputative glycerol uptake operon antiterminator5e-23107
NC_009800:2889928:291142829114282912003576Escherichia coli HS, complete genomeglycerol-3-phosphate responsive antiterminator3e-21101
NC_012759:2757826:277803027780302778605576Escherichia coli BW2952 chromosome, complete genomeputative anti-terminator regulatory protein4e-21100
NC_010473:2963951:298476029847602985335576Escherichia coli str. K-12 substr. DH10B, complete genomepredicted anti-terminator regulatory protein4e-21100
AC_000091:2872000:289285228928522893427576Escherichia coli W3110 DNA, complete genomepredicted anti-terminator regulatory protein4e-21100
NC_014654:1802007:180743018074301808005576Halanaerobium sp. 'sapolanicus' chromosome, complete genomeglycerol-3-phosphate responsive antiterminator, GlpP5e-1994
NC_013199:392450:397166397166397729564Lactobacillus rhamnosus Lc 705, complete genomepredicted ORF1e-1685.9