Pre_GI: BLASTP Hits

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Query: NC_005810:4306716:4323844 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 4323844, End: 4324725, Length: 882

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_015061:4286000:428790442879044288887984Rahnella sp. Y9602 chromosome, complete genomeGlutathione transferase1e-129462
NC_017047:4379989:438179043817904382773984Rahnella aquatilis HX2 chromosome, complete genomeglutathione transferase4e-129461
NC_020260:3457597:347048634704863471472987Cronobacter sakazakii Sp291, complete genomeglutathione S-transferase domain protein1e-123442
NC_009778:3454790:346768034676803468666987Enterobacter sakazakii ATCC BAA-894, complete genomehypothetical protein1e-123442
NC_016010:637535:663488663488664462975Xanthomonas axonopodis pv. citrumelo F1 chromosome, completeglutathione S-transferase3e-106384
NC_007973:1785985:179079417907941791780987Ralstonia metallidurans CH34 chromosome 1, complete sequenceglutathione S-transferase-like protein4e-102371
NC_015433:791364:815973815973816929957Streptococcus suis ST3 chromosome, complete genomeglutathione S-transferase2e-95349
NC_008027:2331617:233161723316172332576960Pseudomonas entomophila L48, complete genomehypothetical protein9e-87320
NC_002947:4484824:450630445063044507281978Pseudomonas putida KT2440, complete genomeglutathione S-transferase domain protein6e-85313
NC_015733:3736104:382905238290523830011960Pseudomonas putida S16 chromosome, complete genomeglutathione S-transferase domain-containing protein1e-84313
NC_008789:1837493:184101418410141841967954Halorhodospira halophila SL1, complete genomeGlutathione S-transferase, C-terminal domain2e-84312
NC_005125:3570385:358378835837883584753966Gloeobacter violaceus PCC 7421, complete genomehypothetical protein2e-82306
NC_019974:1280500:1291534129153412925411008Natronococcus occultus SP4, complete genomeputative glutathione S-transferase6e-79294
NC_013202:606204:6082826082826092831002Halomicrobium mukohataei DSM 12286, complete genomeglutathione S-transferase1e-77289
NC_019964:1961237:196320219632021964194993Halovivax ruber XH-70, complete genomeputative glutathione S-transferase1e-76286
NC_014729:630152:637155637155638096942Halogeometricum borinquense DSM 11551 chromosome, complete genomeglutathione s-transferase2e-72272
NC_013421:1397841:141632914163291417288960Pectobacterium wasabiae WPP163, complete genomeGlutathione transferase6e-72271
NC_009092:2644164:265918126591812660155975Shewanella loihica PV-4, complete genomeglutathione S-transferase8e-70263
NC_009925:5957806:5963387596338759643881002Acaryochloris marina MBIC11017, complete genomeglutathione transferase C terminal domain protein1e-64246
NC_013174:73948:7985179851808851035Jonesia denitrificans DSM 20603, complete genometransferase, putative3e-57222
NC_014210:1471752:1531957153195715329761020Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,Glutathione transferase4e-57221
NC_008686:1383891:1420288142028814213761089Paracoccus denitrificans PD1222 chromosome 1, complete sequenceglutathione S-transferase-like protein1e-55216
NC_020291:1535402:153623215362321537194963Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomeputative glutathione S-transferase4e-46185
NC_008817:228029:232136232136233080945Prochlorococcus marinus str. MIT 9515, complete genomeGlutathione S-transferase C terminus2e-29129