Pre_GI: BLASTP Hits

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Query: NC_005810:4224500:4238252 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 4238252, End: 4239181, Length: 930

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004088:4116676:413181741318174132767951Yersinia pestis KIM, complete genomehomoserine kinase1e-174612
NC_010465:3958766:397391739739173974846930Yersinia pseudotuberculosis YPIII, complete genomehomoserine kinase2e-174611
NC_003143:483395:485857485857486786930Yersinia pestis CO92, complete genomehomoserine kinase2e-174611
NC_008150:4561633:456409545640954565024930Yersinia pestis Antiqua, complete genomehomoserine kinase2e-174611
NC_008149:402599:405061405061405990930Yersinia pestis Nepal516, complete genomehomoserine kinase2e-174611
NC_010159:809663:825845825845826774930Yersinia pestis Angola, complete genomehomoserine kinase2e-174611
NC_006155:713174:713174713174714103930Yersinia pseudotuberculosis IP 32953, complete genomehomoserine kinase2e-174611
NC_009381:3596000:361225136122513613180930Yersinia pestis Pestoides F chromosome, complete genomehomoserine kinase2e-174611
NC_009708:3903598:391873939187393919668930Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehomoserine kinase2e-174611
NC_014029:536000:539350539350540279930Yersinia pestis Z176003 chromosome, complete genomehomoserine kinase2e-174611
NC_017154:478000:481501481501482430930Yersinia pestis D106004 chromosome, complete genomehomoserine kinase2e-174611
NC_017160:479411:483693483693484622930Yersinia pestis D182038 chromosome, complete genomehomoserine kinase2e-174611
NC_017168:601928:617069617069617998930Yersinia pestis A1122 chromosome, complete genomehomoserine kinase2e-174611
NC_017265:3982020:399716139971613998090930Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,homoserine kinase2e-174611
NC_009348:3261500:327350632735063274474969Aeromonas salmonicida subsp. salmonicida A449, complete genomehomoserine kinase6e-105380
NC_015424:3112637:316571931657193166702984Aeromonas veronii B565 chromosome, complete genomeHomoserine kinase4e-104377
NC_014909:121771:130259130259131197939Candidatus Blochmannia vafer str. BVAF chromosome, complete genomehomoserine kinase7e-97353
NC_005061:96536:124937124937125872936Candidatus Blochmannia floridanus, complete genomehomoserine kinase9e-90330
NC_016901:1527877:154654815465481547510963Shewanella baltica OS678 chromosome, complete genomehomoserine kinase2e-84312
NC_009665:1495473:151493215149321515894963Shewanella baltica OS185 chromosome, complete genomehomoserine kinase2e-84312
NC_009052:1394000:141217414121741413136963Shewanella baltica OS155, complete genomehomoserine kinase8e-84310
NC_015177:4042976:404542840454284046363936Pedobacter saltans DSM 12145 chromosome, complete genomehomoserine kinase4e-36152
NC_019904:2327842:235291223529122353847936Echinicola vietnamensis DSM 17526 chromosome, complete genomehomoserine kinase1e-28127
NC_014958:629459:634350634350635258909Deinococcus maricopensis DSM 21211 chromosome, complete genomeHomoserine kinase7e-28124
NC_012526:131000:139076139076140023948Deinococcus deserti VCD115, complete genomeputative Homoserine kinase3e-27122
NC_010118:133256:140444140444141376933Candidatus Sulcia muelleri GWSS, complete genomehomoserine kinase4e-26119
NC_016630:1385719:139504713950471395946900Filifactor alocis ATCC 35896 chromosome, complete genomehomoserine kinase4e-26119
NC_014152:2181360:218405421840542184962909Thermincola sp. JR, complete genomehomoserine kinase2e-26119
NC_015167:2700218:271483027148302715756927Cellulophaga lytica DSM 7489 chromosome, complete genomeHomoserine kinase2e-26119
NC_014328:794000:796923796923797822900Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehomoserine kinase3e-25115
NC_016010:2059791:2086940208694020879531014Xanthomonas axonopodis pv. citrumelo F1 chromosome, completehomoserine kinase8e-24111
NC_016584:3645245:366303536630353663937903Desulfosporosinus orientis DSM 765 chromosome, complete genomehomoserine kinase2e-23110
NC_014804:341663:344588344588345475888Thermococcus barophilus MP chromosome, complete genomehomoserine kinase3e-22106
NC_008346:1499963:152264115226411523543903Syntrophomonas wolfei subsp. wolfei str. Goettingen, completehomoserine kinase3e-22105
NC_003919:2091547:211676721167672117687921Xanthomonas axonopodis pv. citri str. 306, complete genomehomoserine kinase4e-22105
NC_015161:162000:162893162893163807915Deinococcus proteolyticus MRP chromosome, complete genomeHomoserine kinase8e-22104
NC_010688:2400471:242284024228402423808969Xanthomonas campestris pv. campestris, complete genomehypothetical protein3e-21102
NC_014410:2609588:262181026218102622715906Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,homoserine kinase4e-21102
NC_015687:1377367:137930013793001380190891Clostridium acetobutylicum DSM 1731 chromosome, complete genomehomoserine kinase9e-21100
NC_017271:2084219:211364321136432114602960Xanthomonas campestris pv. raphani 756C chromosome, completehomoserine kinase2e-2099.8
NC_017295:1375180:137711313771131378003891Clostridium acetobutylicum EA 2018 chromosome, complete genomeHomoserine kinase (thrB)3e-2099.4
NC_003030:1375764:137769713776971378587891Clostridium acetobutylicum ATCC 824, complete genomeHomoserine kinase (thrB)3e-2099.4
NC_009706:830461:862028862028862930903Clostridium kluyveri DSM 555 chromosome, complete genomehomoserine kinase4e-2098.6
NC_011837:830436:861896861896862804909Clostridium kluyveri NBRC 12016, complete genomehomoserine kinase5e-2098.6
NC_009495:1759759:178032017803201781213894Clostridium botulinum A str. ATCC 3502 chromosome, complete genomehomoserine kinase7e-2098.2
NC_000853:569576:570322570322571167846Thermotoga maritima MSB8, complete genomehomoserine kinase, putative9e-2097.8
NC_012883:1421644:144425514442551445130876Thermococcus sibiricus MM 739, complete genomeHomoserine kinase1e-1997.1
NC_004557:2475030:249713124971312498042912Clostridium tetani E88, complete genomehomoserine kinase3e-1996.3
NC_009633:587562:593504593504594400897Alkaliphilus metalliredigens QYMF chromosome, complete genomehomoserine kinase4e-1995.5
NC_004193:375416:492111492111492995885Oceanobacillus iheyensis HTE831, complete genomehomoserine kinase1e-1894
NC_013722:1425588:144482814448281445796969Xanthomonas albilineans, complete genomeputative homoserine kinase (hsk) (hk) protein2e-1893.2
NC_015555:2359000:237135623713562372261906Thermoanaerobacterium xylanolyticum LX-11 chromosome, completeHomoserine kinase8e-1891.3
NC_013642:323799:324545324545325390846Thermotoga naphthophila RKU-10, complete genomehomoserine kinase1e-1790.5
NC_010483:363525:382361382361383206846Thermotoga sp. RQ2, complete genomehomoserine kinase2e-1790.1
NC_009486:346665:364323364323365168846Thermotoga petrophila RKU-1 chromosome, complete genomehomoserine kinase3e-1789.4
NC_012039:185607:195145195145196023879Campylobacter lari RM2100, complete genomehomoserine kinase4e-1789
NC_016582:4874500:487487748748774875791915Streptomyces bingchenggensis BCW-1 chromosome, complete genomehomoserine kinase5e-1788.6
NC_014479:3079855:310161131016113102540930Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehomoserine kinase7e-1788.2
NC_015636:379000:400343400343401266924Methanothermococcus okinawensis IH1 chromosome, complete genomeHomoserine kinase1e-1687.4
NC_006087:676318:689787689787690758972Leifsonia xyli subsp. xyli str. CTCB07, complete genomehomoserine kinase1e-1687.4
NC_014831:2082304:2085907208590720869861080Thermaerobacter marianensis DSM 12885 chromosome, complete genomehomoserine kinase6e-1685.1
NC_017187:1923733:192373319237331924614882Arcobacter butzleri ED-1, complete genomehomoserine kinase9e-1684.3
NC_015562:1460124:149332414933241494244921Methanotorris igneus Kol 5 chromosome, complete genomeHomoserine kinase4e-1582.4
NC_013769:123958:145249145249146184936Sulfolobus islandicus L.D.8.5 chromosome, complete genomehomoserine kinase2e-1480.1
NC_014166:455378:464132464132465013882Arcobacter nitrofigilis DSM 7299 chromosome, complete genomehomoserine kinase2e-1376.6
NC_008261:2743942:274610927461092746975867Clostridium perfringens ATCC 13124, complete genome4-diphosphocytidyl-2C-methyl-D-erythritol kinase3e-1066.2
NC_002163:129800:135709135709136587879Campylobacter jejuni subsp. jejuni NCTC 11168, complete genomehomoserine kinase6e-1065.1
NC_013947:1363078:137829613782961379210915Stackebrandtia nassauensis DSM 44728 chromosome, complete genomehomoserine kinase4e-0858.9
NC_002937:1634287:165835716583571659217861Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, complete4-diphosphocytidyl-2C-methyl-D-erythritol kinase8e-0754.7
NC_008701:37219:480824808248978897Pyrobaculum islandicum DSM 4184, complete genomehomoserine kinase6e-0652