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Query: NC_005810:3493607:3506403 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 3506403, End: 3506479, Length: 77

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007947:1229807:12359871235987123606377Methylobacillus flagellatus KT, complete genometRNA-Asp2e-0650.8
NC_008322:2637646:26520762652076265215277Shewanella sp. MR-7, complete genometRNA-Asp1e-0548.9
NC_008321:2569315:25837342583734258381077Shewanella sp. MR-4, complete genometRNA-Asp1e-0548.9
NC_008322:2637646:26522102652210265228677Shewanella sp. MR-7, complete genometRNA-Asp1e-0548.9
NC_009901:2915939:29294292929429292950577Shewanella pealeana ATCC 700345, complete genometRNA-Asp1e-0548.9
NC_008577:2818546:28422262842226284230277Shewanella sp. ANA-3 chromosome 1, complete sequencetRNA-Asp1e-0548.9
NC_009901:2915939:29299372929937293001377Shewanella pealeana ATCC 700345, complete genometRNA-Asp1e-0548.9
NC_004347:2668000:26874822687482268755877Shewanella oneidensis MR-1, complete genometRNA-Asp1e-0548.9
NC_009901:2915939:29296032929603292967977Shewanella pealeana ATCC 700345, complete genometRNA-Asp1e-0548.9
NC_008577:2818546:28420932842093284216977Shewanella sp. ANA-3 chromosome 1, complete sequencetRNA-Asp1e-0548.9
NC_004347:2668000:26876162687616268769277Shewanella oneidensis MR-1, complete genometRNA-Asp1e-0548.9
NC_008577:44184:55972559725604877Shewanella sp. ANA-3 chromosome 1, complete sequencetRNA-Asp1e-0548.9
NC_008321:2569315:25838682583868258394477Shewanella sp. MR-4, complete genometRNA-Asp1e-0548.9
NC_013730:3729626:37379653737965373804177Spirosoma linguale DSM 74, complete genometRNA-Asp9e-0648.9
NC_009901:2915939:29297772929777292985377Shewanella pealeana ATCC 700345, complete genometRNA-Asp1e-0548.9