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Query: NC_005810:3272765:3282190 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 3282190, End: 3282492, Length: 303

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017187:1424371:142536514253651425667303Arcobacter butzleri ED-1, complete genomehypothetical protein4e-28123
NC_009850:1498111:149910714991071499409303Arcobacter butzleri RM4018, complete genomeconserved hypothetical protein3e-28123
NC_004369:371109:387675387675387983309Corynebacterium efficiens YS-314, complete genomehypothetical protein1e-1995.1
NC_007907:5428247:543262754326275432926300Desulfitobacterium hafniense Y51, complete genomehypothetical protein9e-25112
NC_010159:1071937:107664510766451076947303Yersinia pestis Angola, complete genomeputative monooxygenase, YdhR9e-54208
NC_008150:3495851:350377735037773504079303Yersinia pestis Antiqua, complete genomehypothetical protein9e-54208
NC_017265:3790750:379623837962383796540303Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein9e-54208
NC_003143:675622:689361689361689663303Yersinia pestis CO92, complete genomehypothetical protein9e-54208
NC_017154:671816:685022685022685324303Yersinia pestis D106004 chromosome, complete genomehypothetical protein9e-54208
NC_017160:676249:687207687207687509303Yersinia pestis D182038 chromosome, complete genomehypothetical protein9e-54208
NC_004088:3923804:393087639308763931178303Yersinia pestis KIM, complete genomehypothetical protein9e-54208
NC_008149:587689:600891600891601193303Yersinia pestis Nepal516, complete genomehypothetical protein9e-54208
NC_009381:460358:471328471328471630303Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein9e-54208
NC_014029:729675:742870742870743172303Yersinia pestis Z176003 chromosome, complete genomehypothetical protein9e-54208
NC_009708:633054:642483642483642785303Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein9e-54208
NC_006155:4062000:406947640694764069778303Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein9e-54208
NC_010634:4001154:400968240096824009984303Yersinia pseudotuberculosis PB1/+, complete genomeputative mono-oxygenase ydhR9e-54208
NC_010465:660207:669636669636669938303Yersinia pseudotuberculosis YPIII, complete genomePutative mono-oxygenase ydhR9e-54208