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Query: NC_005810:2739878:2755853 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 2755853, End: 2756221, Length: 369

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3063016:306575430657543066122369Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein9e-66248
NC_008149:1317109:133308913330891333457369Yersinia pestis Nepal516, complete genomehypothetical protein9e-66248
NC_008150:2681327:269730726973072697675369Yersinia pestis Antiqua, complete genomehypothetical protein9e-66248
NC_004088:1387276:140319014031901403558369Yersinia pestis KIM, complete genomehypothetical protein9e-66248
NC_003143:2992295:300827530082753008643369Yersinia pestis CO92, complete genomehypothetical protein9e-66248
NC_010634:3368000:337288433728843373252369Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein9e-66248
NC_006155:3456488:345922634592263459594369Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein9e-66248
NC_009381:1783886:178779617877961788164369Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein9e-66248
NC_017168:2751027:275376527537652754133369Yersinia pestis A1122 chromosome, complete genomehypothetical protein9e-66248
NC_010465:1273000:128708312870831287451369Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein3e-65246
NC_017986:409899:4241994241994252841086Pseudomonas putida ND6 chromosome, complete genomehypothetical protein8e-1062.4
NC_015424:748785:762577762577763173597Aeromonas veronii B565 chromosome, complete genomehypothetical protein4e-0753.5
NC_004347:103967:122642122642123265624Shewanella oneidensis MR-1, complete genomehypothetical protein4e-0753.5
NC_016616:2112211:213649121364912137378888Dechlorosoma suillum PS chromosome, complete genomehypothetical protein1e-0651.6
NC_007498:2638671:2646511264651126480041494Pelobacter carbinolicus DSM 2380, complete genomehypothetical protein3e-0650.4