Pre_GI: BLASTP Hits

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Query: NC_005810:2739878:2748549 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 2748549, End: 2749724, Length: 1176

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3063016:3072251307225130734261176Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative potassium channel protein0766
NC_008149:1317109:1325785132578513269601176Yersinia pestis Nepal516, complete genomepotassium channel protein0766
NC_004088:1387276:1395886139588613970611176Yersinia pestis KIM, complete genomepotassium channel0766
NC_003143:2992295:3000971300097130021461176Yersinia pestis CO92, complete genomeputative potassium channel protein0766
NC_008150:2681327:2690003269000326911781176Yersinia pestis Antiqua, complete genomeputative potassium channel protein0766
NC_010159:3779129:3785772378577237869471176Yersinia pestis Angola, complete genomepotassium channel protein Kch0766
NC_009381:1783886:1794293179429317954681176Yersinia pestis Pestoides F chromosome, complete genomevoltage-gated potassium channel0766
NC_014029:3047506:3056182305618230573571176Yersinia pestis Z176003 chromosome, complete genomeputative potassium channel protein0766
NC_017154:2999841:3009076300907630102511176Yersinia pestis D106004 chromosome, complete genomeputative potassium channel protein0766
NC_017160:2976683:2981156298115629823311176Yersinia pestis D182038 chromosome, complete genomeputative potassium channel protein0766
NC_017168:2751027:2760262276026227614371176Yersinia pestis A1122 chromosome, complete genomevoltage-gated potassium channel0766
NC_010465:1273000:1279778127977812809531176Yersinia pseudotuberculosis YPIII, complete genomeTrkA-N domain protein0759
NC_010634:3368000:3379380337938033805551176Yersinia pseudotuberculosis PB1/+, complete genomeTrkA domain-containing protein0759
NC_006155:3456488:3465723346572334668981176Yersinia pseudotuberculosis IP 32953, complete genomeputative potassium channel protein, VIC superfamily0759
NC_009708:1284555:1291399129139912925741176Yersinia pseudotuberculosis IP 31758 chromosome, complete genomevoltage-gated potassium channel0759
NC_013364:1596278:1602395160239516036481254Escherichia coli O111:H- str. 11128, complete genomevoltage-gated potassium channel protein Kch3e-56219
NC_007384:2007467:2026020202602020272731254Shigella sonnei Ss046, complete genomeputative potassium channel protein3e-56219
NC_009801:1392696:1397878139787813991311254Escherichia coli E24377A, complete genomepotassium channel protein kch3e-56219
NC_007606:1209132:1213393121339312146461254Shigella dysenteriae Sd197, complete genomeputative potassium channel protein8e-56218
NC_009484:429269:4487494487494499991251Acidiphilium cryptum JF-5 chromosome, complete genomevoltage-gated potassium channel7e-54211
NC_010473:1384000:139698613969861397689704Escherichia coli str. K-12 substr. DH10B, complete genome7e-25115
NC_002689:78297:1008111008111018391029Thermoplasma volcanium GSS1, complete genomeKef-type K+ transport system, predicted NAD-binding component4e-1582.8
NC_011296:801612:8023268023268033481023Thermodesulfovibrio yellowstonii DSM 11347, complete genomepotassium uptake protein, TrkA family8e-1065.1
NC_013849:1396051:139882413988241399351528Ferroglobus placidus DSM 10642 chromosome, complete genomehypothetical protein2e-0963.5
NC_009662:837500:8607008607008622801581Nitratiruptor sp. SB155-2, complete genomepotassium channel protein2e-0860.5
NC_014122:205112:220070220070221065996Methanocaldococcus infernus ME chromosome, complete genomeTrkA-N domain protein9e-0858.2
NC_019978:1477724:1498498149849814995081011Halobacteroides halobius DSM 5150, complete genomeK+ transport system, NAD-binding component3e-0756.6
NC_015968:2583721:258408225840822584951870Enterobacter asburiae LF7a chromosome, complete genomeIon transport protein3e-0756.6
NC_013967:2103968:210396821039682104810843Haloferax volcanii DS2 chromosome, complete genomeIon channel family5e-0652.8
NC_013791:875224:8952738952738962921020Bacillus pseudofirmus OF4 chromosome, complete genomepotassium channel protein5e-0652.8
NC_014166:2217790:2230804223080422319341131Arcobacter nitrofigilis DSM 7299 chromosome, complete genomeIon transport 2 domain-containing protein6e-0652.4
NC_011283:2185462:218652121865212187348828Klebsiella pneumoniae 342 chromosome, complete genometransporter cation channel family8e-0652
NC_016616:2997348:2997348299734829983851038Dechlorosoma suillum PS chromosome, complete genomeK+ transport system, NAD-binding component8e-0652
NC_013850:2103469:212005921200592120892834Klebsiella variicola At-22 chromosome, complete genomeIon transport protein8e-0652
NC_007355:3979729:4001968400196840030111044Methanosarcina barkeri str. fusaro chromosome 1, complete sequencepotassium channel protein8e-0652
NC_021182:4310900:4327777432777743294471671Clostridium pasteurianum BC1, complete genomehypothetical protein9e-0651.6