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Query: NC_005810:2739878:2745239 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 2745239, End: 2746231, Length: 993

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3063016:307574930757493076741993Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative urea transporter3e-145514
NC_008150:2681327:268668826866882687680993Yersinia pestis Antiqua, complete genomeputative urea transporter3e-145514
NC_010159:3779129:378247637824763783468993Yersinia pestis Angola, complete genomeurea transporter3e-145514
NC_003143:2992295:299765629976562998648993Yersinia pestis CO92, complete genomeputative urea transporter3e-145514
NC_008149:1317109:132247013224701323462993Yersinia pestis Nepal516, complete genomeurea transporter3e-145514
NC_004088:1387276:139257113925711393563993Yersinia pestis KIM, complete genomehypothetical protein3e-145514
NC_009381:1783886:179781017978101798802993Yersinia pestis Pestoides F chromosome, complete genomeurea transporter3e-145514
NC_014029:3047506:305286730528673053859993Yersinia pestis Z176003 chromosome, complete genomeputative urea transporter3e-145514
NC_017154:2999841:301257430125743013566993Yersinia pestis D106004 chromosome, complete genomeputative urea transporter3e-145514
NC_017160:2976683:297784129778412978833993Yersinia pestis D182038 chromosome, complete genomeputative urea transporter3e-145514
NC_017168:2751027:276376027637602764752993Yersinia pestis A1122 chromosome, complete genomeurea transporter3e-145514
NC_010465:1273000:127647012764701277462993Yersinia pseudotuberculosis YPIII, complete genomeurea transporter8e-145513
NC_009708:1284555:128808712880871289079993Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeurea transporter8e-145513
NC_006155:3456488:346921834692183470210993Yersinia pseudotuberculosis IP 32953, complete genomeputative urea transporter2e-144512
NC_010634:3368000:338287533828753383867993Yersinia pseudotuberculosis PB1/+, complete genomeurea transporter2e-144512
NC_012779:1966205:197827319782731979250978Edwardsiella ictaluri 93-146, complete genomehypothetical protein9e-60230
NC_002937:1233000:1253139125313912541521014Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completeurea transporter, putative2e-28126
NC_003228:2245181:224518122451812246032852Bacteroides fragilis NCTC 9343, complete genomeputative urea transport protein3e-1066.2