Pre_GI: BLASTP Hits

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Query: NC_005810:2739878:2739878 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 2739878, End: 2741596, Length: 1719

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:3063016:3080384308038430821021719Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,urease alpha subunit01132
NC_008150:2681327:2681327268132726830451719Yersinia pestis Antiqua, complete genomeurease alpha subunit01132
NC_003143:2992295:2992295299229529940131719Yersinia pestis CO92, complete genomeurease alpha subunit01132
NC_008149:1317109:1317109131710913188271719Yersinia pestis Nepal516, complete genomeurease alpha subunit01132
NC_006155:3456488:3474039347403934757571719Yersinia pseudotuberculosis IP 32953, complete genomeurease alpha subunit01132
NC_010634:3368000:3387696338769633894141719Yersinia pseudotuberculosis PB1/+, complete genomeurease, alpha subunit01132
NC_009381:1783886:1802445180244518041631719Yersinia pestis Pestoides F chromosome, complete genomeurease subunit alpha01132
NC_014029:3047506:3047506304750630492241719Yersinia pestis Z176003 chromosome, complete genomeurease alpha subunit01132
NC_017154:2999841:3017209301720930189271719Yersinia pestis D106004 chromosome, complete genomeurease alpha subunit01132
NC_017168:2751027:2768395276839527701131719Yersinia pestis A1122 chromosome, complete genomeurease subunit alpha01132
NC_004088:1387276:1387276138727613889281653Yersinia pestis KIM, complete genomeurease (urea amidohydrolase) alpha subunit01086
NC_012779:1966205:1982413198241319841311719Edwardsiella ictaluri 93-146, complete genomeurease, alpha subunit, putative0991
NC_012559:978419:1002295100229510040131719Laribacter hongkongensis HLHK9, complete genomeUrease, alpha subunit0836
NC_012988:1777618:1777618177761817793361719Methylobacterium extorquens DM4, complete genomeurease subunit alpha0789
NC_013894:672840:6888976888976906001704Thermocrinis albus DSM 14484 chromosome, complete genomeurease, alpha subunit0694
NC_015634:2547144:2547144254714425488531710Bacillus coagulans 2-6 chromosome, complete genomeurease subunit alpha0681
NC_015172:951550:9617019617019634161716Syntrophobotulus glycolicus DSM 8271 chromosome, complete genomeUrease subunit alpha0678
NC_011886:404661:4133244133244150811758Arthrobacter chlorophenolicus A6, complete genomeurease, alpha subunit0676
NC_013406:3329791:3346950334695033486621713Paenibacillus sp. Y412MC10 chromosome, complete genomeurease subunit alpha0667
NC_007510:913411:9316939316939333991707Burkholderia sp. 383 chromosome 1, complete sequenceUrease, alpha subunit0666
NC_020302:2116468:2124190212419021259051716Corynebacterium halotolerans YIM 70093 = DSM 44683, completeurease subunit alpha0662
NC_004369:1051013:1056198105619810579131716Corynebacterium efficiens YS-314, complete genomeurease alpha subunit0658
NC_012803:361127:3720533720533737681716Micrococcus luteus NCTC 2665, complete genomeurease0652
NC_015681:1201926:1205992120599212076951704Thermodesulfatator indicus DSM 15286 chromosome, complete genomeurease subunit alpha0649
NC_013008:1307392:1335770133577013374761707Escherichia coli O157:H7 str. TW14359 chromosome, complete genomeurease subunit alpha0648
NC_013209:2536500:2541534254153425432401707Acetobacter pasteurianus IFO 3283-01, complete genomeurease alpha subunit0647
NC_017100:2538461:2542741254274125444471707Acetobacter pasteurianus IFO 3283-03, complete genomeurease alpha subunit0647
NC_017108:2535798:2540078254007825417841707Acetobacter pasteurianus IFO 3283-12, complete genomeurease alpha subunit0647
NC_017111:2535000:2540096254009625418021707Acetobacter pasteurianus IFO 3283-32, complete genomeurease alpha subunit0647
NC_017121:2535803:2540083254008325417891707Acetobacter pasteurianus IFO 3283-07, complete genomeurease alpha subunit0647
NC_017125:2538441:2542721254272125444271707Acetobacter pasteurianus IFO 3283-22, complete genomeurease alpha subunit0647
NC_017146:2538483:2542763254276325444691707Acetobacter pasteurianus IFO 3283-26, complete genomeurease alpha subunit0647
NC_013353:3853082:3867452386745238691581707Escherichia coli O103:H2 str. 12009, complete genomeurease alpha subunit UreC0645
AP010958:3853082:3867452386745238691581707Escherichia coli O103:H2 str. 12009 DNA, complete genomeurease alpha subunit UreC0645
NC_007516:2420264:2436939243693924386481710Synechococcus sp. CC9605, complete genomeurease, alpha subunit0645
NC_014006:924417:9443679443679460761710Sphingobium japonicum UT26S chromosome 1, complete genomeurease alpha subunit0644
NC_000915:53715:7552775527772361710Helicobacter pylori 26695, complete genomeurease beta subunit (urea amidohydrolase) (ureB)0643
NC_012973:49208:6985069850715591710Helicobacter pylori B38 chromosome, complete genomeurease subunit beta0643
NC_014555:47372:6756967569692781710Helicobacter pylori PeCan4 chromosome, complete genomeurease subunit beta0643
NC_014560:53750:7611176111778201710Helicobacter pylori SJM180 chromosome, complete genomeurease subunit beta0643
NC_018939:53715:7552775527772361710Helicobacter pylori 26695 chromosome, complete genomeurease subunit beta0643
NC_003911:1791878:1831078183107818327871710Silicibacter pomeroyi DSS-3, complete genomeurease, alpha subunit0642
NC_017506:2993679:3009796300979630114991704Marinobacter adhaerens HP15 chromosome, complete genomeurease subunit alpha-like protein0640
NC_008343:2389710:2411596241159624133051710Granulibacter bethesdensis CGDNIH1, complete genomeurease alpha subunit0638
NC_009437:2579161:2614481261448126161931713Caldicellulosiruptor saccharolyticus DSM 8903, complete genomeurease subunit alpha0638
NC_008752:3902637:3902637390263739043551719Acidovorax avenae subsp. citrulli AAC00-1, complete genomeurease, alpha subunit0634
NC_007292:623765:6472736472736489761704Candidatus Blochmannia pennsylvanicus str. BPEN, complete genomeputative urease structural subunit C (alpha)5e-179627
NC_012704:947409:9499819499819521732193Corynebacterium kroppenstedtii DSM 44385, complete genomeurease, alpha subunit/beta subunit7e-179627
NC_020075:637420:6469426469426486451704Candidatus Blochmannia chromaiodes str. 640, complete genomeurease subunit alpha8e-179627
NC_017192:1063955:1075380107538010770801701Arcobacter sp. L, complete genomeurease alpha subunit3e-178625
NC_014909:589677:5946925946925963951704Candidatus Blochmannia vafer str. BVAF chromosome, complete genomeurease, alpha subunit2e-177622
NC_008686:1180388:1180388118038811820761689Paracoccus denitrificans PD1222 chromosome 1, complete sequenceurease, alpha subunit3e-171602
NC_008212:2978786:3000156300015630018681713Haloquadratum walsbyi DSM 16790, complete genomeurease, alpha subunit1e-167590
NC_012988:4292815:4322308432230843240231716Methylobacterium extorquens DM4, complete genomeurease subunit alpha3e-162572
NC_017275:985516:9895329895329912021671Sulfolobus islandicus HVE10/4 chromosome, complete genomeurease subunit alpha1e-161570
NC_015435:825853:8241928241928258561665Metallosphaera cuprina Ar-4 chromosome, complete genomeurease subunit alpha6e-160564
NC_009142:2725000:2734499273449927363251827Saccharopolyspora erythraea NRRL 2338, complete genomeurease alpha subunit5e-157554
NC_009664:1434974:1453797145379714554761680Kineococcus radiotolerans SRS30216, complete genomeUrease1e-128460