Pre_GI: BLASTP Hits

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Query: NC_005810:2091930:2107845 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 2107845, End: 2108420, Length: 576

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:2213500:221517022151702215745576Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative metal-binding enzyme5e-109392
NC_004088:2491303:249346324934632494038576Yersinia pestis KIM, complete genomehypothetical protein5e-109392
NC_008150:1593500:160975916097591610334576Yersinia pestis Antiqua, complete genomehypothetical protein5e-109392
NC_010465:2383219:238537923853792385954576Yersinia pseudotuberculosis YPIII, complete genomeprotein of unknown function DUF9915e-109392
NC_003143:2309500:232544623254462326021576Yersinia pestis CO92, complete genomehypothetical protein5e-109392
NC_010159:2546590:254758625475862548161576Yersinia pestis Angola, complete genomehypothetical protein5e-109392
NC_008149:1718000:173405817340581734633576Yersinia pestis Nepal516, complete genomehypothetical protein5e-109392
NC_009381:1205900:120806012080601208635576Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein5e-109392
NC_009708:2347350:234834623483462348921576Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein5e-109392
NC_014029:2285323:228748322874832288058576Yersinia pestis Z176003 chromosome, complete genomehypothetical protein5e-109392
NC_017154:2306421:232235023223502322925576Yersinia pestis D106004 chromosome, complete genomehypothetical protein5e-109392
NC_017160:2212806:221496622149662215541576Yersinia pestis D182038 chromosome, complete genomehypothetical protein5e-109392
NC_017168:3433804:343596434359643436539576Yersinia pestis A1122 chromosome, complete genomehypothetical protein5e-109392
NC_006155:2378526:239441323944132394988576Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein3e-108390
NC_010634:2297000:231230923123092312884576Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein3e-108390
NC_008800:2592500:259261925926192593179561Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein1e-81301
NC_008258:1934479:195988919598891960455567Shigella flexneri 5 str. 8401, complete genomehypothetical protein8e-59226
NC_011415:2153243:217516521751652175737573Escherichia coli SE11 chromosome, complete genomehypothetical protein1e-58225
NC_004547:2810151:283431128343112834895585Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein3e-54211
NC_014562:1772842:178801617880161788579564Pantoea vagans C9-1 chromosome, complete genomeProtein yecM4e-48190