Pre_GI: BLASTP Hits

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Query: NC_005810:1976000:1997930 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 1997930, End: 1998607, Length: 678

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1715035:173808417380841738761678Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative DNA-binding protein1e-131468
NC_003143:1880000:190164819016481902325678Yersinia pestis CO92, complete genomeputative DNA-binding protein1e-131468
NC_010519:2033980:204929120492912049959669Haemophilus somnus 2336 chromosome, complete genomeYheO domain-containing protein6e-31134
NC_008309:1851189:186828118682811868949669Haemophilus somnus 129PT, complete genomehypothetical protein6e-31134
NC_016642:1234500:123646212364621237160699Pseudovibrio sp. FO-BEG1 chromosome, complete genomeYheO domain-containing protein2e-27122
NC_016818:362548:363672363672364394723Rahnella aquatilis CIP 78.65 = ATCC 33071 chromosome, completehypothetical protein4e-27121
NC_013508:3387272:340979634097963410512717Edwardsiella tarda EIB202, complete genomeYheO domain protein4e-26117
NC_010718:1865992:186743818674381868103666Natranaerobius thermophilus JW/NM-WN-LF, complete genomeYheO domain protein3e-23108
NC_006322:2658587:267102426710242671689666Bacillus licheniformis ATCC 14580, complete genomeDctR5e-22104
NC_006270:2657726:267016326701632670828666Bacillus licheniformis ATCC 14580, complete genomehypothetical DNA binding protein5e-22104
NC_016047:2631511:264125326412532641912660Bacillus subtilis subsp. spizizenii TU-B-10 chromosome, completeprotein DctR8e-21100
NC_006155:4062000:407107340710734071705633Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein9e-1993.6
NC_010634:4001154:401127940112794011911633Yersinia pseudotuberculosis PB1/+, complete genomeYheO domain-containing protein9e-1993.6
NC_010465:660207:667709667709668341633Yersinia pseudotuberculosis YPIII, complete genomeYheO domain protein9e-1993.6
NC_009708:633054:640556640556641188633Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein9e-1993.6
NC_014023:24000:256302563026292663Bacillus megaterium QM B1551 plasmid pBM700, complete sequencehypothetical protein1e-1893.2
NC_018870:2479114:248606524860652486703639Thermacetogenium phaeum DSM 12270 chromosome, complete genomeYheO domain-containing protein2e-1892.4
NC_014639:1538782:155778115577811558431651Bacillus atrophaeus 1942 chromosome, complete genometranscriptional regulator3e-1788.6
CP002207:1538782:155778115577811558431651Bacillus atrophaeus 1942, complete genometranscriptional regulator3e-1788.6
NC_014328:3294086:331075033107503311400651Clostridium ljungdahlii ATCC 49587 chromosome, complete genomehypothetical protein4e-1788.2
NC_015737:2050219:206413120641312064769639Clostridium sp. SY8519, complete genomehypothetical protein6e-1787.8
NC_015589:7678:174131741318183771Desulfotomaculum ruminis DSM 2154 chromosome, complete genomeYheO-like domain-containing protein6e-1787.4
NC_020211:379000:392352392352392978627Serratia marcescens WW4, complete genomeputative DNA-binding protein3e-1685.5
NC_005810:3272765:328026732802673280890624Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein4e-1685.1
NC_010159:1071937:107824710782471078873627Yersinia pestis Angola, complete genome3e-1685.1
NC_008149:587689:598965598965599591627Yersinia pestis Nepal516, complete genomehypothetical protein3e-1685.1
NC_008150:3495851:350537935053793506005627Yersinia pestis Antiqua, complete genomehypothetical protein3e-1685.1
NC_009381:460358:469402469402470028627Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein3e-1685.1
NC_014029:729675:740944740944741570627Yersinia pestis Z176003 chromosome, complete genomehypothetical protein3e-1685.1
NC_017154:671816:683096683096683722627Yersinia pestis D106004 chromosome, complete genomehypothetical protein3e-1685.1
NC_017160:676249:685281685281685907627Yersinia pestis D182038 chromosome, complete genomehypothetical protein3e-1685.1
NC_017265:3790750:379784037978403798466627Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein3e-1685.1
NC_012225:47800:720617206172714654Brachyspira hyodysenteriae WA1, complete genomehypothetical protein containing PAS domain9e-1477
NC_013385:90331:986709867099344675Ammonifex degensii KC4, complete genomeYheO domain protein1e-1376.6
NC_019908:2401577:241691724169172417570654Brachyspira pilosicoli P43/6/78 chromosome, complete genomehypothetical protein2e-1375.9
NC_018604:2253539:226632122663212266974654Brachyspira pilosicoli WesB complete genomeYheO domain protein2e-1375.9
NC_014330:768232:803531803531804184654Brachyspira pilosicoli 95/1000 chromosome, complete genomehypothetical protein2e-1375.9
NC_003143:675622:687471687471688061591Yersinia pestis CO92, complete genomehypothetical protein3e-1375.1
NC_014323:292958:307957307957308613657Herbaspirillum seropedicae SmR1 chromosome, complete genomehypothetical protein5e-1374.7
NC_017243:2190000:222037622203762221029654Brachyspira intermedia PWS/A chromosome, complete genomehypothetical protein8e-1373.9
NC_015873:380485:408787408787409494708Megasphaera elsdenii DSM 20460, complete genomeYheO-like protein4e-1271.6
NC_013093:2895511:289850528985052899167663Actinosynnema mirum DSM 43827, complete genomeYheO domain protein2e-1169.7
NC_015138:201323:204550204550205182633Acidovorax avenae subsp. avenae ATCC 19860 chromosome, completeYheO-like domain-containing protein7e-1167.4
NC_008752:166877:168138168138168770633Acidovorax avenae subsp. citrulli AAC00-1, complete genomeYheO domain protein1e-1067
NC_014150:2994000:300882030088203009473654Brachyspira murdochii DSM 12563 chromosome, complete genomeYheO domain protein6e-1064.3
NC_007511:1681764:168496116849611685599639Burkholderia sp. 383 chromosome 2, complete sequencehypothetical protein1e-0757
NC_018720:47984:533545335454181828Bifidobacterium asteroides PRL2011 chromosome, complete genomeYheO-like protein9e-0857
NC_006351:2759708:279517027951702795802633Burkholderia pseudomallei K96243 chromosome 2, complete sequencehypothetical protein2e-0755.8
NC_008463:1188951:120005712000571200689633Pseudomonas aeruginosa UCBPP-PA14, complete genomehypothetical protein2e-0755.8
NC_002516:4321000:432494843249484325580633Pseudomonas aeruginosa PAO1, complete genomehypothetical protein3e-0755.5