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Query: NC_005810:1976000:1980464 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 1980464, End: 1980655, Length: 192

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1715035:172062017206201720811192Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein7e-30129
NC_009381:2009842:202556620255662025757192Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein7e-30129
NC_003143:1880000:188420018842001884391192Yersinia pestis CO92, complete genomehypothetical protein7e-30129
NC_010159:2955562:297188329718832972074192Yersinia pestis Angola, complete genomeDsrB protein7e-30129
NC_013421:2004088:201060220106022010805204Pectobacterium wasabiae WPP163, complete genomeDextransucrase DSRB9e-23105
NC_012917:2971702:298581029858102986013204Pectobacterium carotovorum subsp. carotovorum PC1, complete genomehypothetical protein1e-21102
NC_012947:1769438:181251418125141812702189Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein5e-22102
NC_004547:1873390:193030119303011930504204Erwinia carotovora subsp. atroseptica SCRI1043, complete genomehypothetical protein2e-21101
NC_021066:601029:623942623942624130189Raoultella ornithinolytica B6, complete genomehypothetical protein3e-2097.1
NC_012880:1765920:178848117884811788672192Dickeya dadantii Ech703, complete genomehypothetical protein1e-1994.7
NC_012779:1820244:182302218230221823225204Edwardsiella ictaluri 93-146, complete genomehypothetical protein1e-1891.7
NC_013592:1668092:169225816922581692458201Dickeya dadantii Ech586, complete genomeDextransucrase DSRB2e-1684.3