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Query: NC_005810:1130251:1140663 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 1140663, End: 1142333, Length: 1671

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1136000:1141926114192611435961671Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein01042
NC_008150:650899:6573326573326590021671Yersinia pestis Antiqua, complete genomehypothetical protein01042
NC_003143:1233128:1240596124059612422661671Yersinia pestis CO92, complete genomehypothetical protein01042
NC_008149:3251196:3261608326160832632781671Yersinia pestis Nepal516, complete genomehypothetical protein01042
NC_014029:1283500:1289793128979312914631671Yersinia pestis Z176003 chromosome, complete genomehypothetical protein01042
NC_017154:1225500:1231886123188612335561671Yersinia pestis D106004 chromosome, complete genomehypothetical protein01042
NC_017160:1507500:1518055151805515197251671Yersinia pestis D182038 chromosome, complete genomehypothetical protein01042
NC_017168:4155143:4162612416261241642821671Yersinia pestis A1122 chromosome, complete genomehypothetical protein01042
NC_010159:1417993:1424748142474814264181671Yersinia pestis Angola, complete genome01039
NC_004088:3382148:3392560339256033940501491Yersinia pestis KIM, complete genomehypothetical protein0910
NC_009381:2939782:2950194295019429513391146Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein0692
NC_015167:1911758:1923980192398019257401761Cellulophaga lytica DSM 7489 chromosome, complete genomehypothetical protein1e-88327
NC_007912:529500:5486875486875504021716Saccharophagus degradans 2-40, complete genomehypothetical protein8e-78291
NC_008060:3155133:3169656316965631713591704Burkholderia cenocepacia AU 1054 chromosome 1, complete sequencehypothetical protein1e-62241
NC_009381:2939782:295161529516152951863249Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein4e-41169
NC_013132:4355363:4373275437327543749931719Chitinophaga pinensis DSM 2588, complete genomehypothetical protein3e-37157
NC_012587:2326000:2333031233303123347191689Rhizobium sp. NGR234, complete genomehypothetical protein2e-33144
NC_015737:1976000:1995168199516819968501683Clostridium sp. SY8519, complete genomehypothetical protein1e-1171.6
NC_013895:1332832:137041413704141371304891Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, complete6e-0962.8
NC_018607:805966:8201298201298218081680Brachyspira pilosicoli B2904 chromosome, complete genomehypothetical protein1e-0655.1
NC_014330:609982:6242646242646259431680Brachyspira pilosicoli 95/1000 chromosome, complete genomeputative chromosome segregation ATPase1e-0655.1
NC_010163:614634:6343996343996360841686Acholeplasma laidlawii PG-8A chromosome, complete genomeputative chromosome segregation ATPase9e-0652.4