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Query: NC_004917:340997:343003 Helicobacter hepaticus ATCC 51449, complete genome

Start: 343003, End: 343731, Length: 729

Host Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017281:722000:737338737338738021684Campylobacter jejuni subsp. jejuni S3 chromosome, complete genomeFerric siderophore transport system, periplasmic binding protein TonB2e-1376.3
NC_003912:767500:782888782888783571684Campylobacter jejuni RM1221, complete genomeTonB2e-1376.3
NC_002163:687925:704442704442705125684Campylobacter jejuni subsp. jejuni NCTC 11168, complete genometonB transport protein2e-1376.3
NC_014802:716699:732723732723733406684Campylobacter jejuni subsp. jejuni ICDCCJ07001 chromosome, completehypothetical protein2e-1376.3
NC_009715:399159:400543400543401394852Campylobacter curvus 525.92 chromosome, complete genomeprotein TonB2e-1375.9
NC_017279:692500:708104708104708802699Campylobacter jejuni subsp. jejuni IA3902 chromosome, completeTonB transport protein3e-1375.9
NC_005090:1082213:108612510861251086829705Wolinella succinogenes DSM 1740, complete genomehypothetical protein1e-1170.1
NC_012039:412837:443383443383444036654Campylobacter lari RM2100, complete genomeTonB domain protein1e-1067
NC_013501:1140390:115644611564461157222777Rhodothermus marinus DSM 4252, complete genomeTonB family protein2e-0756.2