Pre_GI: BLASTP Hits

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Query: NC_004741:2593012:2599752 Shigella flexneri 2a str. 2457T, complete genome

Start: 2599752, End: 2600054, Length: 303

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a highly virulent strain that has been widely used for genetic and clinical research. Causes enteric disease. This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011092:76993:769937699377295303Salmonella enterica subsp. enterica serovar Schwarzengrund strphosphoglucosamine mutase3e-52203
NC_002937:1374532:1374532137453213758841353Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completephosphoglucosamine mutase1e-24111
NC_013173:302375:3023753023753037241350Desulfomicrobium baculatum DSM 4028, complete genomephosphoglucosamine mutase3e-24110
NC_008011:213386:2415222415222428771356Lawsonia intracellularis PHE/MN1-00, complete genomephosphomannomutase9e-24108
NC_008783:177161:1823091823091836611353Bartonella bacilliformis KC583, complete genomephosphoglucosamine mutase1e-23108
NC_007498:1148249:1174000117400011753821383Pelobacter carbinolicus DSM 2380, complete genomephosphohexomutase2e-22104
NC_007645:1245927:1246761124676112480981338Hahella chejuensis KCTC 2396, complete genomephosphoglucosamine mutase3e-21100
NC_013939:1023443:1032872103287210342331362Deferribacter desulfuricans SSM1, complete genomephosphoglucosamine mutase9e-2198.6
NC_002620:229856:2362742362742376531380Chlamydia muridarum Nigg, complete genomephosphoglucomutase/phosphomannomutase family protein6e-2095.9
NC_010524:3094303:3100393310039331017271335Leptothrix cholodnii SP-6, complete genomephosphoglucosamine mutase1e-1995.1
NC_009089:117980:1617101617101631161407Clostridium difficile 630, complete genomephosphoglucomutase/phosphomannomutase mutase4e-1993.6
NC_008321:1523323:1545415154541515467671353Shewanella sp. MR-4, complete genomephosphoglucosamine mutase4e-1890.1
NC_008700:2701500:2706734270673427080921359Shewanella amazonensis SB2B, complete genomephosphoglucosamine mutase4e-1890.1
NC_009654:1123709:1138932113893211402781347Marinomonas sp. MWYL1, complete genomephosphoglucosamine mutase5e-1889.7
NC_014758:1489761:1503571150357115049231353Calditerrivibrio nitroreducens DSM 19672 chromosome, completephosphoglucosamine mutase5e-1889.7
NC_009997:3583166:3587649358764935890011353Shewanella baltica OS195, complete genomephosphoglucosamine mutase6e-1889.4
NC_016901:3530248:3536089353608935374411353Shewanella baltica OS678 chromosome, complete genomephosphoglucosamine mutase6e-1889.4
NC_009665:3460906:3466347346634734676991353Shewanella baltica OS185 chromosome, complete genomephosphoglucosamine mutase9e-1889
NC_008322:1595500:1616858161685816182101353Shewanella sp. MR-7, complete genomephosphoglucosamine mutase1e-1788.6
NC_021150:4311902:4324819432481943261561338Azotobacter vinelandii CA6, complete genomephosphoglucosamine mutase1e-1788.6
NC_012560:4311906:4324823432482343261601338Azotobacter vinelandii DJ, complete genomephosphoglucosamine mutase1e-1788.6
NC_015581:771482:7788467788467801831338Thioalkalimicrobium cyclicum ALM1 chromosome, complete genomephosphoglucosamine mutase1e-1788.6
NC_015318:1583839:1604759160475916061171359Hippea maritima DSM 10411 chromosome, complete genomephosphoglucosamine mutase2e-1787.8
NC_012691:3126500:3131020313102031323571338Tolumonas auensis DSM 9187, complete genomephosphoglucosamine mutase2e-1787.4
NC_004129:957890:9683869683869697231338Pseudomonas fluorescens Pf-5, complete genomephosphoglucosamine mutase2e-1787.4
NC_011663:1709003:1735300173530017366521353Shewanella baltica OS223 chromosome, complete genomephosphoglucosamine mutase5e-1786.7
NC_020541:2264521:2286313228631322876651353Rhodanobacter sp. 2APBS1, complete genomephosphoglucosamine mutase6e-1786.3
NC_008345:3394154:3402428340242834037801353Shewanella frigidimarina NCIMB 400, complete genomephosphoglucosamine mutase1e-1684.7
NC_015565:287900:2918482918482931821335Desulfotomaculum carboxydivorans CO-1-SRB chromosome, completephosphoglucosamine mutase5e-1683.2
NC_005061:96536:1087721087721101301359Candidatus Blochmannia floridanus, complete genomePGM/PMM-family protein6e-1682.8
NC_014909:86000:1133041133041146651362Candidatus Blochmannia vafer str. BVAF chromosome, complete genomephosphoglucosamine mutase7e-1682.4
NC_004557:2677155:2702536270253627038821347Clostridium tetani E88, complete genomephosphoglucosamine mutase2e-1581.3
NC_003454:983681:9950989950989964561359Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completePhosphoacetylglucosamine mutase2e-1580.9
NC_016887:1035458:1035458103545810368311374Nocardia cyriacigeorgica GUH-2, complete genomephosphoglucosamine mutase2e-1580.9
NC_015589:366296:3682843682843696181335Desulfotomaculum ruminis DSM 2154 chromosome, complete genomephosphoglucosamine mutase2e-1580.9
NC_014538:1942500:1942707194270719440501344Thermoanaerobacter sp. X513 chromosome, complete genomephosphoglucosamine mutase1e-1478.6
NC_009922:2556033:2557984255798425593331350Alkaliphilus oremlandii OhILAs, complete genomephosphoglucosamine mutase3e-1477
NC_011830:923424:9290239290239303601338Desulfitobacterium hafniense DCB-2, complete genomephosphoglucosamine mutase4e-1476.6
NC_020075:114790:1212231212231225811359Candidatus Blochmannia chromaiodes str. 640, complete genomephosphoglucosamine mutase5e-1476.3
NC_008702:1514707:1518249151824915196041356Azoarcus sp. BH72, complete genomeputative phosphoglucomutase5e-1476.3
NC_010001:473354:4771024771024784481347Clostridium phytofermentans ISDg, complete genomephosphoglucosamine mutase6e-1476.3
NC_016893:563890:5720655720655734051341Wigglesworthia glossinidia endosymbiont of Glossina morsitansphosphoglucosamine mutase7e-1475.9
NC_009697:3629250:3636427363642736377761350Clostridium botulinum A str. ATCC 19397 chromosome, completephosphoglucosamine mutase1e-1375.5
NC_009698:3526359:3533536353353635348851350Clostridium botulinum A str. Hall chromosome, complete genomephosphoglucosamine mutase1e-1375.5
NC_011567:139598:1552421552421565851344Anoxybacillus flavithermus WK1, complete genomePhosphomannomutase9e-1475.5
NC_014479:188009:1880091880091893551347Bacillus subtilis subsp. spizizenii str. W23 chromosome, completephosphoglucosamine mutase1e-1375.1
NC_016632:74569:9084990849921951347Serratia symbiotica str. 'Cinara cedri' chromosome, completephosphoglucosamine mutase1e-1375.1
NC_009699:3753599:3763270376327037646191350Clostridium botulinum F str. Langeland chromosome, complete genomephosphoglucosamine mutase1e-1375.1
NC_017297:3752000:3761956376195637632331278Clostridium botulinum F str. 230613 chromosome, complete genome1e-1375.1
NC_009725:200071:2023422023422036881347Bacillus amyloliquefaciens FZB42, complete genomeYbbT1e-1375.1
NC_020410:198000:2023632023632037301368Bacillus amyloliquefaciens subsp. plantarum UCMB5036 completephosphoglucosamine mutase1e-1375.1
NC_014551:199500:2032912032912046371347Bacillus amyloliquefaciens DSM 7, complete genomephosphoglucomutase GlmM1e-1375.1
NC_017188:177500:1812701812701826161347Bacillus amyloliquefaciens TA208 chromosome, complete genomephosphoglucosamine mutase1e-1375.1
NC_017190:182449:1860801860801874261347Bacillus amyloliquefaciens LL3 chromosome, complete genomephosphoglucomutase GlmM1e-1375.1
NC_017191:183500:1871801871801885261347Bacillus amyloliquefaciens XH7 chromosome, complete genomephosphoglucosamine mutase1e-1375.1
UCMB5137:3857960:3861040386104038623861347Bacillus atrophaeus UCMB-5137phosphoglucosamine mutase1e-1375.1
NC_020272:3706722:3723500372350037248461347Bacillus amyloliquefaciens IT-45, complete genomephosphoglucosamine mutase1e-1375.1
NC_012658:3744000:3751354375135437527031350Clostridium botulinum Ba4 str. 657 chromosome, complete genomephosphoglucosamine mutase2e-1374.7
NC_010516:3724312:3731491373149137328401350Clostridium botulinum B1 str. Okra, complete genomephosphoglucosamine mutase1e-1374.7
NC_012563:3921859:3928342392834239296911350Clostridium botulinum A2 str. Kyoto, complete genomephosphoglucosamine mutase1e-1374.7
NC_010520:3753875:3761005376100537623541350Clostridium botulinum A3 str. Loch Maree, complete genomephosphoglucosamine mutase1e-1374.7
NC_010723:298954:3019093019093032521344Clostridium botulinum E3 str. Alaska E43, complete genomephosphoglucosamine mutase2e-1373.9
NC_011978:493800:4966244966244979101287Thermotoga neapolitana DSM 4359, complete genomePhosphoglucosamine mutase3e-1373.9
NC_014171:109280:1635021635021648481347Bacillus thuringiensis BMB171 chromosome, complete genomephosphoglucosamine mutase4e-1373.6
NC_017208:108134:1652721652721666181347Bacillus thuringiensis serovar chinensis CT-43 chromosome, completephosphoglucosamine mutase4e-1373.6
NC_009848:161373:1613731613731627191347Bacillus pumilus SAFR-032, complete genomephosphoglucosamine mutase4e-1373.2
NC_015958:2206032:2223290222329022246331344Thermoanaerobacter wiegelii Rt8.B1 chromosome, complete genomephosphoglucosamine mutase5e-1372.8
NC_009617:234782:2380132380132393591347Clostridium beijerinckii NCIMB 8052 chromosome, complete genomephosphoglucosamine mutase7e-1372.8
NC_014829:178000:1897741897741911351362Bacillus cellulosilyticus DSM 2522 chromosome, complete genomephosphoglucosamine mutase7e-1372.4
NC_017341:2303005:2316296231629623176511356Staphylococcus aureus subsp. aureus str. JKD6008 chromosome,putative phosphoglucosamine mutase1e-1272
NC_002951:2208813:2222102222210222234571356Staphylococcus aureus subsp. aureus COL, complete genomephosphoglucosamine mutase GlmM1e-1272
NC_011653:1728000:1734085173408517353771293Thermosipho africanus TCF52B, complete genomephosphoglucosamine mutase2e-1271.6
NC_012673:1540000:1542912154291215442701359Exiguobacterium sp. AT1b, complete genomephosphoglucosamine mutase1e-1271.6
NC_012880:3915500:3923311392331139246481338Dickeya dadantii Ech703, complete genomephosphoglucosamine mutase1e-1271.6
NC_014328:4387303:4397430439743043987791350Clostridium ljungdahlii ATCC 49587 chromosome, complete genomephosphoglucosamine mutase1e-1271.6
NC_019815:782987:7957967957967971361341Candidatus Kinetoplastibacterium crithidii (ex Angomonas deaneiphosphoglucosamine mutase2e-1271.2
NC_005139:2731623:2751994275199427533341341Vibrio vulnificus YJ016 chromosome I, complete sequencephosphomannomutase2e-1270.9
NC_013716:4885776:4898677489867749000141338Citrobacter rodentium ICC168, complete genomephosphoglucosamine mutase2e-1270.9
NC_019897:329945:3500453500453513851341Thermobacillus composti KWC4 chromosome, complete genomephosphoglucosamine mutase2e-1270.9
NC_015968:4117835:4155189415518941565261338Enterobacter asburiae LF7a chromosome, complete genomephosphoglucosamine mutase3e-1270.5
NC_021184:592501:6038606038606051941335Desulfotomaculum gibsoniae DSM 7213, complete genomephosphoglucosamine mutase3e-1270.5
NC_010718:237962:2511022511022524301329Natranaerobius thermophilus JW/NM-WN-LF, complete genomephosphoglucosamine mutase4e-1270.1
NC_003413:603157:6068056068056081721368Pyrococcus furiosus DSM 3638, complete genomephospho-sugar mutase5e-1269.7
NC_011134:1222739:1242488124248812438401353Streptococcus equi subsp. zooepidemicus str. MGCS10565, completephosphoglucosamine mutase GlmM5e-1269.7
NC_008601:1733940:1742066174206617433971332Francisella tularensis subsp. novicida U112, complete genomephosphoglucosamine mutase7e-1269.3
NC_015555:386000:3970303970303983731344Thermoanaerobacterium xylanolyticum LX-11 chromosome, completephosphoglucosamine mutase8e-1269.3
NC_012121:1676367:1680775168077516821301356Staphylococcus carnosus subsp. carnosus TM300, complete genomephosphoglucosamine-mutase9e-1268.9
NC_000961:828416:8316308316308329971368Pyrococcus horikoshii OT3, complete genomephospho-sugar mutase9e-1268.9
NC_000868:1168819:1189702118970211910721371Pyrococcus abyssi GE5, complete genomephosphomannomutase (pmm)1e-1168.6
NC_020063:528296:5329455329455342821338Enterobacteriaceae bacterium strain FGI 57, complete genomephosphoglucosamine mutase1e-1168.6
NC_018665:139646:1574931574931588481356Exiguobacterium antarcticum B7 chromosome, complete genomePhosphoglucosamine mutase1e-1168.2
NC_010556:141374:1575471575471589021356Exiguobacterium sibiricum 255-15, complete genomephosphoglucosamine mutase2e-1168.2
NC_007880:1703346:1711427171142717127581332Francisella tularensis subsp. holarctica, complete genomephosphoglucosamine mutase2e-1167.8
NC_008369:1702885:1711059171105917123901332Francisella tularensis subsp. holarctica OSU18, complete genomephosphoglucomutase2e-1167.8
NC_009749:1699152:1707326170732617086571332Francisella tularensis subsp. holarctica FTA, complete genomephosphoglucosamine mutase2e-1167.8
NC_003155:5987000:6007048600704860084061359Streptomyces avermitilis MA-4680, complete genomephosphoglucomutase/phosphomannomutase2e-1167.8
NC_008245:66852:8208982089834201332Francisella tularensis subsp. tularensis FSC 198, complete genomephosphoglucosamine mutase2e-1167.8
NC_009257:151737:1669741669741683051332Francisella tularensis subsp. tularensis WY96-3418 chromosome,phosphoglucosamine mutase2e-1167.8
NC_016933:66854:8209182091834221332Francisella tularensis TIGB03 chromosome, complete genomephosphoglucosamine mutase2e-1167.8
NC_016937:66854:8209182091834221332Francisella tularensis subsp. tularensis TI0902 chromosome,phosphoglucosamine mutase2e-1167.8
NC_012004:1053682:1060950106095010623021353Streptococcus uberis 0140J, complete genomephosphoglucosamine mutase4e-1166.6
NC_003888:5114147:5148674514867451500321359Streptomyces coelicolor A3(2), complete genomephospho-sugar mutase1e-1065.5
NC_015953:4385419:4426624442662444279821359Streptomyces sp. SirexAA-E chromosome, complete genomephosphoglucosamine mutase1e-1065.5
NC_013929:4136742:4138798413879841402071410Streptomyces scabiei 87.22 chromosome, complete genomephosphoglucosamine mutase2e-1064.7
NC_018750:4728870:4756123475612347574811359Streptomyces venezuelae ATCC 10712, complete genomePhosphoglucosamine mutase2e-1064.7
NC_007681:1455425:1463928146392814652861359Methanosphaera stadtmanae DSM 3091, complete genomepredicted phosphomannomutase4e-1063.5
NC_002528:404545:4207974207974221311335Buchnera aphidicola str. APS (Acyrthosiphon pisum), completeMrsA protein4e-1063.2
NC_017259:388000:4034114034114047451335Buchnera aphidicola str. Ua (Uroleucon ambrosiae) chromosome,MrsA protein5e-1063.2
NC_004193:241480:2541222541222554621341Oceanobacillus iheyensis HTE831, complete genomephosphoglucomutase6e-1062.8
NC_004545:392685:4017644017644031251362Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genomeputative phosphoglucosamine mutase1e-0961.6
NC_014666:7641060:7641060764106076424421383Frankia sp. EuI1c chromosome, complete genomephosphoglucosamine mutase3e-0960.8
NC_006624:1952554:1971867197186719732161350Thermococcus kodakarensis KOD1, complete genomephosphohexomutase3e-0960.5
NC_004344:257471:2699772699772713171341Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis,hypothetical protein4e-0960.1
NC_019814:320260:3366583366583380101353Candidatus Kinetoplastibacterium blastocrithidii (ex Strigomonasphosphoglucosamine mutase4e-0960.1
NC_020299:149118:1655111655111668661356Candidatus Kinetoplastibacterium oncopeltii TCC290E, completephosphoglucosamine mutase4e-0960.1
NC_016051:1385490:1385490138549013868391350Thermococcus sp. AM4 chromosome, complete genomephosphomannomutase / phosphoglucosamine mutase2e-0857.4
NC_009515:616432:6365936365936379661374Methanobrevibacter smithii ATCC 35061, complete genomephosphomannomutase, ManB7e-0856.2
NC_015676:1736375:1774504177450417758051302Methanosalsum zhilinae DSM 4017 chromosome, complete genomephosphoglucosamine mutase7e-0855.8
NC_015499:119200:1596171596171609331317Thermodesulfobium narugense DSM 14796 chromosome, complete genomePhosphoglucosamine mutase2e-0754.7
NC_014254:18193:2767127671289751305Methanohalobium evestigatum Z-7303 plasmid pMETEV01, completephosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I2e-0754.7
NC_017095:1461520:1469665146966514709691305Fervidobacterium pennivorans DSM 9078 chromosome, complete genomephosphoglucosamine mutase2e-0754.3
NC_018876:2563725:2573880257388025751811302Methanolobus psychrophilus R15 chromosome, complete genomephosphoglucomutase/phosphomannomutase alpha/beta/subunit1e-0652
NC_013926:183057:1946201946201959391320Aciduliprofundum boonei T469 chromosome, complete genomephosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I2e-0651.2
NC_008541:3282415:3286869328686932882271359Arthrobacter sp. FB24 chromosome 1, complete sequencephosphoglucosamine mutase2e-0651.2
NC_016109:3525588:3526627352662735279551329Kitasatospora setae KM-6054, complete genomeputative phosphoglucosamine mutase2e-0650.8
NC_011886:2950411:2957028295702829583891362Arthrobacter chlorophenolicus A6, complete genomephosphoglucosamine mutase2e-0650.8