Query: NC_004668:2198027 Enterococcus faecalis V583, complete genome
Start: 2198027, End: 2270099, Length: 72073
Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: This strain is one of the first vancomycin-resistant strains isolated. This isolate came from a blood culture derived from a chronically-infected patient in 1987 from Barnes Hospital in St. Louis, Missouri, USA. This strain was found to lack the cytolysin gene and a surface adhesin, Esp, that contributes to urinary tract infections. Mobile genetic elements make up one quarter of the genome. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_014828:2038692 | 2038692 | 2087315 | 48624 | Ethanoligenens harbinense YUAN-3 chromosome, complete genome | 2e-22 | 117 | BLASTN svg | BLASTP svg |
NC_011898:3303381* | 3303381 | 3339341 | 35961 | Clostridium cellulolyticum H10, complete genome | 6e-19 | 105 | BLASTN svg | BLASTP svg |
NC_009089:1283000 | 1283000 | 1324218 | 41219 | Clostridium difficile 630, complete genome | 6e-19 | 105 | BLASTN svg | BLASTP svg |
NC_005707:12735 | 12735 | 37842 | 25108 | Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence | 2e-18 | 103 | BLASTN svg | BLASTP svg |
NC_016048:2873669 | 2873669 | 2907698 | 34030 | Oscillibacter valericigenes Sjm18-20, complete genome | 1e-17 | 101 | BLASTN svg | BLASTP svg |
NC_013895:1332832 | 1332832 | 1380099 | 47268 | Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, complete | 4e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_013798:1778758 | 1778758 | 1803165 | 24408 | Streptococcus gallolyticus UCN34, complete genome | 4e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_009089:3889811 | 3889811 | 3921485 | 31675 | Clostridium difficile 630, complete genome | 6e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_009089:581655 | 581655 | 606563 | 24909 | Clostridium difficile 630, complete genome | 6e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_013792:109203* | 109203 | 135099 | 25897 | Bacillus pseudofirmus OF4 plasmid pBpOF4-01, complete sequence | 2e-12 | 83.8 | BLASTN svg | BLASTP svg |
NC_021175:1597613 | 1597613 | 1621108 | 23496 | Streptococcus oligofermentans AS 1.3089, complete genome | 9e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_016048:3063888* | 3063888 | 3106427 | 42540 | Oscillibacter valericigenes Sjm18-20, complete genome | 2e-09 | 73.8 | BLASTN svg | BLASTP svg |
NC_013316:4095905 | 4095905 | 4129996 | 34092 | Clostridium difficile R20291, complete genome | 2e-09 | 73.8 | BLASTN svg | BLASTP svg |
NC_002758:434462 | 434462 | 452818 | 18357 | Staphylococcus aureus subsp. aureus Mu50, complete genome | 3e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_003909:3587695* | 3587695 | 3606099 | 18405 | Bacillus cereus ATCC 10987, complete genome | 3e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_008600:3643905* | 3643905 | 3663189 | 19285 | Bacillus thuringiensis str. Al Hakam, complete genome | 3e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_012472:3661912* | 3661912 | 3681190 | 19279 | Bacillus cereus 03BB102, complete genome | 3e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_014828:1019533* | 1019533 | 1065232 | 45700 | Ethanoligenens harbinense YUAN-3 chromosome, complete genome | 3e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_012471:719000* | 719000 | 751220 | 32221 | Streptococcus equi subsp. equi 4047, complete genome | 1e-07 | 67.9 | BLASTN svg | BLASTP svg |
NC_012781:2552723* | 2552723 | 2588304 | 35582 | Eubacterium rectale ATCC 33656, complete genome | 1e-07 | 67.9 | BLASTN svg | BLASTP svg |
NC_012781:700226* | 700226 | 735492 | 35267 | Eubacterium rectale ATCC 33656, complete genome | 1e-07 | 67.9 | BLASTN svg | BLASTP svg |
NC_016048:2343500* | 2343500 | 2361329 | 17830 | Oscillibacter valericigenes Sjm18-20, complete genome | 1e-07 | 67.9 | BLASTN svg | BLASTP svg |
NC_012781:3315614 | 3315614 | 3354728 | 39115 | Eubacterium rectale ATCC 33656, complete genome | 8e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_009089:428075 | 428075 | 466356 | 38282 | Clostridium difficile 630, complete genome | 8e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_009089:3935500* | 3935500 | 3979165 | 43666 | Clostridium difficile 630, complete genome | 8e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_006958:1872849 | 1872849 | 1893179 | 20331 | Corynebacterium glutamicum ATCC 13032, complete genome | 8e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_003450:1871377 | 1871377 | 1902883 | 31507 | Corynebacterium glutamicum ATCC 13032, complete genome | 8e-06 | 61.9 | BLASTN svg | BLASTP svg |