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Query: NC_004668:3053119:3057707 Enterococcus faecalis V583, complete genome

Start: 3057707, End: 3058507, Length: 801

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is one of the first vancomycin-resistant strains isolated. This isolate came from a blood culture derived from a chronically-infected patient in 1987 from Barnes Hospital in St. Louis, Missouri, USA. This strain was found to lack the cytolysin gene and a surface adhesin, Esp, that contributes to urinary tract infections. Mobile genetic elements make up one quarter of the genome. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017316:2581781:258741425874142588214801Enterococcus faecalis OG1RF chromosome, complete genomeWxL domain surface protein2e-140498
NC_017316:2581781:258665525866552587413759Enterococcus faecalis OG1RF chromosome, complete genomeUbiD family decarboxylase3e-41168
NC_004668:3053119:305694830569483057706759Enterococcus faecalis V583, complete genomehypothetical protein4e-41168
NC_004668:3053119:305851230585123059246735Enterococcus faecalis V583, complete genomehypothetical protein2e-31135
NC_017316:2581781:258821925882192588953735Enterococcus faecalis OG1RF chromosome, complete genomeUbiD family decarboxylase1e-30133
NC_012984:2681548:268154826815482682120573Lactobacillus plantarum JDM1, complete genomeextracellular protein3e-1375.5
NC_008527:125723:141098141098141571474Lactococcus lactis subsp. cremoris SK11, complete genomecell surface protein4e-0962