Pre_GI: BLASTP Hits

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Query: NC_004668:3053119:3055759 Enterococcus faecalis V583, complete genome

Start: 3055759, End: 3056835, Length: 1077

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is one of the first vancomycin-resistant strains isolated. This isolate came from a blood culture derived from a chronically-infected patient in 1987 from Barnes Hospital in St. Louis, Missouri, USA. This strain was found to lack the cytolysin gene and a surface adhesin, Esp, that contributes to urinary tract infections. Mobile genetic elements make up one quarter of the genome. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017316:2581781:2585470258547025865491080Enterococcus faecalis OG1RF chromosome, complete genomecell wall surface anchor family protein0645
NC_008527:125723:1393231393231404531131Lactococcus lactis subsp. cremoris SK11, complete genomecell surface protein8e-59227
NC_014554:3164599:3171134317113431721951062Lactobacillus plantarum subsp. plantarum ST-III chromosome,hypothetical protein1e-22107
NC_008525:606986:612292612292613263972Pediococcus pentosaceus ATCC 25745, complete genomecell surface protein4e-1686.3
NC_012473:46000:6349063490645691080Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequencehypothetical protein4e-1479.3
NC_014331:57769:7887578875799991125Bacillus cereus biovar anthracis str. CI plasmid pCI-XO1, completeputative nucleotidyltransferase4e-1272.8
NC_012656:67949:7884478844799681125Bacillus anthracis str. A0248 plasmid pXO1, complete sequencepXO1-665e-1272.4
NC_012579:72715:7892778927800121086Bacillus anthracis str. CDC 684 plasmid pX01, complete sequencehypothetical protein6e-1272
NC_007322:57710:7861978619797041086Bacillus anthracis str. 'Ames Ancestor' plasmid pXO1, completehypothetical protein6e-1272
NC_015978:412856:439699439699440634936Lactobacillus sanfranciscensis TMW 1.1304 chromosome, completehypothetical protein3e-0859.7