Pre_GI: BLASTP Hits

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Query: NC_004631:948054:981029 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 981029, End: 981190, Length: 162

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016832:948029:978704978704978865162Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,hypothetical protein4e-25113
NC_017046:2026672:203863820386382038799162Salmonella enterica subsp. enterica serovar Typhimurium str. 798hypothetical protein2e-23107
NC_016863:2029340:204130620413062041467162Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative cytoplasmic protein2e-23107
NC_016857:2027311:203927720392772039438162Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative cytoplasmic protein2e-23107
NC_016856:2085283:209311420931142093275162Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative cytoplasmic protein2e-23107
NC_016810:2027311:203927720392772039438162Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein2e-23107