Pre_GI: BLASTP Hits

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Query: NC_004631:948054:970921 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Start: 970921, End: 973881, Length: 2961

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016832:948029:9685969685969715562961Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12,Type III restriction system endonuclease02008
NC_011745:2209288:2242621224262122455812961Escherichia coli ED1a chromosome, complete genomeType III restriction-modification system site-specific deoxyribonuclease01929
NC_013124:1439915:1449743144974314527242982Acidimicrobium ferrooxidans DSM 10331, complete genometype III restriction protein res subunit01078
NC_014366:2826575:2826575282657528296103036Gamma proteobacterium HdN1, complete genomeType III restriction enzyme, res subunit01075
NC_010170:4463000:4489211448921144922163006Bordetella petrii, complete genometype III restriction enzyme01066
NC_010002:4572573:4602520460252046055253006Delftia acidovorans SPH-1, complete genometype III restriction protein res subunit01063
NC_008752:166877:1790811790811820772997Acidovorax avenae subsp. citrulli AAC00-1, complete genometype III restriction enzyme, res subunit01053
NC_008609:206313:2265992265992295742976Pelobacter propionicus DSM 2379, complete genometype III restriction enzyme, res subunit01019
NC_015381:4363005:4379289437928943822973009Burkholderia gladioli BSR3 chromosome 1, complete sequencetype III restriction enzyme, res subunit01013
NC_020387:149890:1613651613651643582994Dehalococcoides mccartyi BTF08, complete genometype III restriction enzyme, res subunit0987
NC_007519:1782067:1797091179709118000632973Desulfovibrio alaskensis G20 chromosome, complete genometype III restriction system endonuclease0984
NC_010694:436500:4584244584244614323009Erwinia tasmaniensis, complete genomeType III restriction enzyme, res subunit0981
NC_012724:1:1339713397164413045Burkholderia glumae BGR1 chromosome 1, complete genomeType III restriction system endonuclease0941
NC_019972:110500:1195841195841225863003Methanomethylovorans hollandica DSM 15978 plasmid pMETHO01,restriction endonuclease0823
NC_013411:2191514:2205716220571622086702955Geobacillus sp. Y412MC61, complete genomeType III site-specific deoxyribonuclease0765
NC_014915:1331459:1345661134566113486152955Geobacillus sp. Y412MC52 chromosome, complete genomeType III site-specific deoxyribonuclease0765
NC_014206:2266000:2268768226876822717222955Geobacillus sp. C56-T3 chromosome, complete genometype III site-specific deoxyribonuclease0756
NC_020301:1486695:1488551148855114915172967Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genomeputative type III restriction enzyme, res subunit0754
NC_010161:1844452:1846296184629618492712976Bartonella tribocorum CIP 105476, complete genomerestriction enzyme of type III restriction-modification system0751
NC_010161:2050816:2052693205269320556682976Bartonella tribocorum CIP 105476, complete genomerestriction enzyme of type III restriction-modification system0751
NC_007681:542494:5546865546865576732988Methanosphaera stadtmanae DSM 3091, complete genometype III restriction-modification system, restriction subunit0660
NC_014828:2038692:2059061205906120621893129Ethanoligenens harbinense YUAN-3 chromosome, complete genomeType III site-specific deoxyribonuclease0651
NC_011666:2109274:2122339212233921252872949Methylocella silvestris BL2, complete genometype III restriction protein res subunit0642
NC_015942:1920693:1931310193131019343363027Acidithiobacillus ferrivorans SS3 chromosome, complete genometype III restriction protein res subunit4e-171602
NC_014218:882118:8821188821188850842967Arcanobacterium haemolyticum DSM 20595 chromosome, complete genomeType III site-specific deoxyribonuclease2e-167590
NC_013172:606387:6224256224256254303006Brachybacterium faecium DSM 4810, complete genomerestriction endonuclease1e-159564
NC_012917:985617:9875939875939905892997Pectobacterium carotovorum subsp. carotovorum PC1, complete genomeType III site-specific deoxyribonuclease6e-156552
NC_009454:136468:1451591451591481853027Pelotomaculum thermopropionicum SI, complete genomerestriction endonuclease1e-155550
NC_012880:3529017:3543250354325035462342985Dickeya dadantii Ech703, complete genomeType III site-specific deoxyribonuclease4e-154545
NC_016633:3069518:3126123312612331291613039Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomerestriction endonuclease1e-153544
NC_013410:1591500:1592956159295615960033048Fibrobacter succinogenes subsp. succinogenes S85 chromosome,type III site-specific deoxyribonuclease6e-150532
NC_013037:6281164:6300484630048463035403057Dyadobacter fermentans DSM 18053, complete genometype III restriction protein res subunit3e-145516
NC_020207:559310:5626435626435657533111Enterococcus faecium NRRL B-2354, complete genomeType III restriction enzyme, res subunit DEAD, DEAH box helicase3e-144513
NC_002936:1004570:1018023101802310210823060Dehalococcoides ethenogenes 195, complete genometype III restriction-modification system, restriction endonuclease subunit7e-144512
NC_014169:1099024:1122307112230711255313225Bifidobacterium longum subsp. longum JDM301 chromosome, completetype III restriction enzyme5e-140499
NC_002927:960369:9779229779229810083087Bordetella bronchiseptica RB50, complete genometype III restriction enzyme1e-139498
NC_015554:3808529:3821326382132638244393114Alteromonas sp. SN2 chromosome, complete genometype III restriction-modification system restriction subunit8e-140498
NC_010655:1808657:1820014182001418230403027Akkermansia muciniphila ATCC BAA-835, complete genometype III restriction protein res subunit9e-139494
NC_017267:2326443:2337748233774823408103063Xanthomonas oryzae pv. oryzicola BLS256 chromosome, completetype III restriction enzyme1e-138494
NC_010831:1224000:1235518123551812385923075Chlorobium phaeobacteroides BS1, complete genometype III restriction protein res subunit2e-138494
NC_015635:3860570:3864724386472438678013078Microlunatus phosphovorus NM-1, complete genometype III restriction-modification system restriction subunit6e-138492
NC_008786:3845988:3852592385259238556513060Verminephrobacter eiseniae EF01-2, complete genometype III restriction enzyme, res subunit4e-137489
NC_010337:2950500:2955172295517229582403069Heliobacterium modesticaldum Ice1, complete genometype iii restriction enzyme, res subunit8e-124445
NC_014377:1943476:1960072196007219631703099Thermosediminibacter oceani DSM 16646 chromosome, complete genomeType III site-specific deoxyribonuclease1e-121438
NC_008942:1198000:1224818122481812280483231Methanocorpusculum labreanum Z, complete genomehypothetical protein6e-118426
NC_008054:1030994:1036955103695510392282274Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, complete9e-117422
NC_021184:1484352:1498357149835715014253069Desulfotomaculum gibsoniae DSM 7213, complete genomerestriction endonuclease8e-117422
NC_010644:231486:2430022430022456652664Elusimicrobium minutum Pei191, complete genometype III restriction protein res subunit2e-116420
NC_018867:10238:6040760407634903084Dehalobacter sp. CF chromosome, complete genomeType III restriction enzyme, res subunit:DEAD/DEAH box helicase, N-terminal6e-115416
NC_008261:421000:4345364345364377003165Clostridium perfringens ATCC 13124, complete genometype III restriction-modification system, Res subunit6e-114412
NC_019897:73957:1020561020561047552700Thermobacillus composti KWC4 chromosome, complete genomerestriction endonuclease1e-109398
NC_020244:3961337:3970317397031739733193003Bacillus subtilis XF-1, complete genometype III restriction-modification system restriction subunit4e-99363
NC_018939:1583653:1597219159721916001222904Helicobacter pylori 26695 chromosome, complete genometype III restriction enzyme R protein (res)1e-74281
NC_000915:1583967:1597196159719616000992904Helicobacter pylori 26695, complete genometype III restriction enzyme R protein (res)1e-74281
NC_017371:1601452:1614780161478016176892910Helicobacter pylori Gambia94/24 chromosome, complete genometype III restriction enzyme2e-74281
NC_011837:2567691:2570619257061925724841866Clostridium kluyveri NBRC 12016, complete genomehypothetical protein4e-74280
NC_014555:1477934:1486883148688314897952913Helicobacter pylori PeCan4 chromosome, complete genometype III restriction enzyme2e-72274
NC_017378:1489818:1503018150301815059362919Helicobacter pylori Puno120 chromosome, complete genometype III restriction enzyme9e-71269
NC_011498:1571840:1582157158215715850662910Helicobacter pylori P12, complete genometype III R-M system restriction enzyme3e-69264
NC_017367:1505780:1517499151749915204142916Helicobacter pylori F57, complete genomeType III restriction enzyme3e-68260
NC_017365:1466500:1478518147851814814332916Helicobacter pylori F30, complete genomeType III restriction enzyme5e-68259
NC_006570:1625909:1642525164252516453982874Francisella tularensis subsp. tularensis Schu 4, complete genomeType III restriction enzyme7e-67256
NC_008245:1625715:1642331164233116452042874Francisella tularensis subsp. tularensis FSC 198, complete genomeType III restriction enzyme7e-67256
NC_016933:1702500:1718275171827517211482874Francisella tularensis TIGB03 chromosome, complete genomeRestriction endonuclease7e-67256
NC_016937:1625752:1642368164236816452412874Francisella tularensis subsp. tularensis TI0902 chromosome,Restriction endonuclease7e-67256
NC_008601:1560482:1577093157709315799602868Francisella tularensis subsp. novicida U112, complete genomerestriction endonuclease4e-67256
NC_007880:508407:5084075084075112802874Francisella tularensis subsp. holarctica, complete genomeType III restriction enzyme8e-66252
NC_009749:510266:5102665102665131392874Francisella tularensis subsp. holarctica FTA, complete genometype III restriction enzyme8e-66252
NC_008369:514995:5121255121255149982874Francisella tularensis subsp. holarctica OSU18, complete genometype III site-specific deoxyribonuclease2e-65251
NC_013520:533803:5357455357455386992955Veillonella parvula DSM 2008, complete genometype III restriction protein res subunit1e-61239
NC_016751:142237:1615801615801644532874Marinitoga piezophila KA3 chromosome, complete genomerestriction endonuclease8e-61236
NC_010677:353839:3538393538393565652727Francisella tularensis subsp. mediasiatica FSC147, complete genometype III restriction enzyme1e-57225
NC_011837:3226500:3238737323873732417152979Clostridium kluyveri NBRC 12016, complete genomehypothetical protein5e-55216
NC_009706:3291330:3307253330725333102132961Clostridium kluyveri DSM 555 chromosome, complete genomeType III restriction-modification system, restriction subunit6e-55216
NC_017354:1465925:1474762147476214771072346Helicobacter pylori 52 chromosome, complete genomehypothetical protein3e-51204
NC_010067:2488141:2488141248814124911162976Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, completehypothetical protein1e-47192
NC_010610:1178430:1209912120991212128872976Lactobacillus fermentum IFO 3956, complete genomerestriction endonuclease2e-46188
NC_008497:1575884:1583420158342015863952976Lactobacillus brevis ATCC 367, complete genomeRestriction endonuclease1e-45186
NC_011837:2567691:2572491257249125736781188Clostridium kluyveri NBRC 12016, complete genomehypothetical protein1e-45185
NC_017372:748097:7499627499627520042043Helicobacter pylori India7 chromosome, complete genomeputative type III restriction enzyme R protein (Res)8e-44179
NC_015975:923812:9314639314639344592997Lactobacillus ruminis ATCC 27782 chromosome, complete genometype III restriction-modification system enzyme2e-43178
NC_013198:1030970:1039970103997010429452976Lactobacillus rhamnosus GG, complete genometype III DNA restriction-modification system5e-43176
NC_011745:5114500:5120053512005351216781626Escherichia coli ED1a chromosome, complete genome6e-21103
NC_008054:1030994:103641510364151036909495Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, complete3e-1481.6
NC_017354:1465925:147714414771441477677534Helicobacter pylori 52 chromosome, complete genome1e-1275.9
NC_003198:378844:3968763968763998502975Salmonella enterica subsp. enterica serovar Typhi str. CT18,3e-1171.2
NC_008618:1095000:109952610995261100227702Bifidobacterium adolescentis ATCC 15703, complete genometype III restriction enzyme9e-1066.6
NC_007164:1434305:1455325145532514579012577Corynebacterium jeikeium K411, complete genomeputative DNA restriction-modification system, restriction enzyme1e-0759.3
NC_012846:1888000:188841718884171888710294Bartonella grahamii as4aup, complete genome1e-0656.2
NC_011004:4073916:4079396407939640820802685Rhodopseudomonas palustris TIE-1, complete genometype III restriction protein res subunit3e-0655.1